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Hormone-sensitive lipase (HSL) is mainly present in adipose tissue where it hydrolyses diacylglycerol. Although expression of HSL has also been reported in the brain, its presence in different cellular compartments is uncertain, and its role in regulating brain lipid metabolism remains hitherto unexplored. We hypothesized HSL might play a role in regulating the availability of bioactive lipids nec
BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of
Increasingly, scholarly debates and policy developments on citizen participation in energy transitions have included calls for ‘energy democracy’ and active forms of ‘energy citizenship’. The concepts are tightly connected to the debate on energy transition, and the need for a decentralised energy system, based on renewable energy and increased local energy ownership. The two concepts exist in par
The study frames a traditional industry in transition with the aim to understand the ways in which a work-identity is formed in the service economy along the west coast of Sweden. More specifically, we want to understand how diversified inshore commercial fisheries are discursively established and negotiated as a service enterprising subject in three everyday relationships; authorities, customers
During mammalian ocular development, several signaling pathways control the spatiotemporal highly defined realization of the three-dimensional eye architecture. Given the complexity of these inductive signals, the developing eye is a sensitive organ for several diseases. In this study, we investigated a Dkk1+/- haploinsufficiency during eye development, resulting in coloboma and anterior eye defec
There is (or should be) an archived specimen, a reference copy if you like, for all living and fossil species that have been described scientifically. These physical specimens, so-called name-bearing type specimens, are housed at museums or academic institutes around the world for researchers to study and perhaps compare with their own material. But what about our own species, Homo sapiens?.
In recent years, scientists have advocated the use of targeted therapies in the form of drugs that modulate genes and proteins that are directly associated with cancer progression and metastasis. Malignant melanoma is a dreadful cancer type that has been associated with the rapid dissemination of primary tumors to multiple sites, including bone, brain, liver and lungs. The discovery that approxima
The aim of this paper was to examine how useable and inclusive the city is from the perspective of older bicyclists. Methods used were quantitative questionnaires and qualitative focus group interviews. Participants were people aged 65 years or older. The results showed that respondents were fairly satisfied with the transport infrastructure design. However, other road users seemed to complicate c
This article investigates American Airlines AAirpass offering. The aim of this case study is to outline the background as to why American Airlines opted to run this offering, examining the decision making and implications. This case also includes teaching notes and a PowerPoint presentation.
Forskargruppen bedriver forskning kring förutsättningar och rehabilitering för ett hälsosamt liv där rörelse och aktivitet är i fokus. Forskning som bedrivs i gruppen syftar också till att förbättra förståelsen för påverkan på människans strukturer, funktioner, aktiviteter och delaktighet i omgivande Iiv. Forskagruppens arbete omfattar hela kedjan från hälsopromotion till rehabilitering, genom heResearch within the group concerns conditions and rehabilitation for a healthy life, with a focus on movement and activity. Research within the group also aims to improve understanding of effects on human structure, functions, activities, and participation in society. Research within the group includes the line from health promotion to rehabilitation, throughout the lifespan. Other areas are work-
Med vår forskning vill vi förstå och främja människors psykiska hälsa, aktivitet och delaktighet och bidra till att människor kan leva ett så meningsfullt liv som möjligt och delta i samhället trots psykisk ohälsa. Att utveckla, utvärdera och implementera återhämtningsinriktade insatser som ger stöd i olika livssituationer och miljöer är därför centralt. Vi vänder oss till olika målgrupper såsomWith our research, we want to understand and promote persons’ mental health, activity and participation and as a result help them to live as meaningful lives as possible and participate in society despite mental ill health. Developing, evaluating and implementing recovery-oriented interventions that help in different life situations and in different environments is therefore critical. We address
AI och digitalisering är en snabbt växande del av utvecklingen av nästan alla ingenjörssystem och kommer att förändra samhället och industrin i grunden. Profilområdets spetskunskap kring teknologier, metoder, algoritmer och mjukvara för att möjliggöra robusta, säkra, effektiva och lärandebaserade system är helt nödvändig i samhällets digitala omställning.AI and digitalization are a rapidly growing part of the development of almost all engineering systems and will fundamentally change society and industry. The profile area's cutting-edge knowledge of technologies, methods, algorithms, and software to enable robust, secure, efficient, and learning-based systems is essential in society's digital transformation.
The knowledge concerning electricity consumption, and especially load demand, in Swedish commercial buildings is very limited. The current study deals with methods for electricity consumption indicator development and application of the different methodologies on measured data. Typical load shapes and consumption indicators are developed for four different types of commercial buildings: schools, h
