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The cellular hallmarks of Parkinson's disease (PD) are the loss of nigral dopaminergic neurons and the formation of α-synuclein-enriched Lewy bodies and Lewy neurites in the remaining neurons. Based on the topographic distribution of Lewy bodies established after autopsy of brains from PD patients, Braak and coworkers hypothesized that Lewy pathology primes in the enteric nervous system and spread
OBJECTIVES: The purpose of this study was to assess the association between structural changes in human atria, age, and history of atrial fibrillation (AF). BACKGROUND: Development of fibrosis in atrial walls is associated with deterioration of atrial conduction and predisposes to AF in experiment. Human data, however, are scarce, and whether fibrosis is a cause or consequence of AF is not known.
Long-term oxygen therapy (LTOT) improves the survival time in hypoxemic chronic obstructive pulmonary disease. Despite warnings about potential dangers, a considerable number of patients continue to smoke while on LTOT. The incidence of burn injuries related to LTOT is unknown. The aim of this study was to estimate the rate of burn injury requiring health care contact during LTOT.
The Maputo Declaration was launched in 2003 as a response to the stagnation of African agriculture. The signatories agreed that 10% of public expenditure should be spent on agriculture in an effort to increase agricultural productivity. This paper examines to what degree the goal of the Maputo declaration has been reached. Little to no evidence was found for a direct positive impact on agricultura
There is an ongoing shift to mobility in business IT, as well as in the consumer space. Users do not demand mobile availability anymore, they simply expect the ability to access business IT with consumer devices. Stemming from this demand, mobile business intelligence (BI) has emerged as a response from the BI industry. Thus, mobile BI is an extension of traditional BI into mobile devices. In line
Video on Demand (VoD) is a service that delivers video seamlessly to the consumer on demand. This thesis examines the consumers’ opinion on the different VoD services that exists on the Swedish market. To conduct our research we collected quantitative data by using a survey and then conducted a qualitative analysis. As a theoretical framework we used our own modified version of The DeLone and
En uppsats som testar strategin Dogs of the Dow på svenska börsen. Uppsatsen tar även hänsyn till återköp som en parameter i denna strategi. Syftet med uppsatsen är att undersöka huruvida Dogs of the Dow kan generera en högre avkastning än ett jämförelseindex. Vidare syftar uppsatsen till att undersöka om en utvecklad variant av strategin kan skapa bättre avkastning än ursprungsstrategin och inde
The aim of this essay is to apply the theories of metaphor from Conceptual Metaphor Theory on a work of allegorical interpretation of the Bible – more specifically, Gregory of Nyssa’s The Life of Moses – and discuss what theological questions and perspectives arises from that. My primary question is thus: how can Gregory of Nyssa’s way of interpreting, and giving meaning to, objects in The Life of
En undersökning av Paul Bowles debutroman The Sheltering Sky utifrån filosofen Martin Heideggers tankar om existensens skarpskurna konturer, hämtade ur Sein und Ziet. Detta för att blotta romanens underliggande tendenser. Uppsatsen driver också en allmän diskussion om litteraturens och filosofins släktskap som pekar tillbaka till försokraterna och som kulminerar i 1900-talets idéhistoriska kuliss.
Principen om barnets bästa ska vara avgörande i alla frågor som rör vårdnad, boende och umgänge. Den bärande principen återfinns i både FN:s barnkonvention och i föräldrabalken. Principen ska fungera som en rättslig vägledning vid alla utredningar i mål som rör barn, men det finns ingen universellt fastslagen definition av vad som faktiskt är barnets bästa. Utgångspunkterna är att bedöma barnets bThe principle of the best interests of the child must be decisive in every legal process regarding children. The operative principle is found in both the UN Convention on the Rights of the Child, and the Swedish Parental Code. The principle should serve as a legal guide in all investigations regarding children. Yet there is no universally established definition of the actual meaning of the best in
Syftet med studien är att undersöka hur svenska konsumenter mellan 18 år och äldre förhåller sig till hållbara last mile-leveranser vid användandet av e-handel, för att med utgångspunkt i konsumenternas värdeskapande använda detta som underlag för huruvida teorin om the seven rights of logistics borde uppdateras för att inkludera ett bredare hållbarhetstänk. För att kunna undersöka detta består up
Uppsatsen syftar till att undersöka ockupationsrätten enligt internationell humanitär rätt, med särskilt fokus på inledandet och avslutandet av en ockupation. Vidare kommer uppsatsen att analysera de utmaningar som är förknippade med ett sådant avslutande. I granskningen av komplexiteten som omger avslutandet av en ockupation kommer 2005 års tillbakadragande från Gaza, samt ockupationen av Irak meThis thesis aims to investigate the law of occupation under international humanitarian law, specifically focusing on the beginning and ending of an occupation. The thesis will also explore the challenges associated with its termination. By examining the complexity regarding the ending of an occupation, the 2005 “disengagement” from Gaza and the occupation of Iraq 2003-2005, will be used. The thesi
Following the continual degradation of climate, the issue of climate change has increasingly been integrated in world politics. The European Union has itself implemented climate policies to adverse the tendency. However, the union has also given rise to the principle of free movement, a concept tightly connected to the EU’s carbon intensive transport sector. Research has shown the need for the EU
This thesis investigates the rhetoric of populist leaders during the Covid-19 pandemic. By examining statements from three different presidents, Brazil's Jair Bolsonaro, Mexico´s Andrés Manuel López Obrador, and Nicaragua´s Daniel Ortega and explores whether they used rhetoric that downplayed the threat of COVID-19. Through a qualitative content analysis, the rhetoric of these presidents is ex
Stakeholder engagement is viewed as crucial for environmental governance, especially in regard to common-pool resources (CPRs), such as river basins. This study investigates the conceptualisation of stakeholder engagement in Ireland’s third cycle River Basin Management Plan (RBMP). The study examines the underlying presumptions and representations of stakeholder engagement in governmental discours
Syftet med denna uppsats är att utreda och analysera hur införandet av the Principal Purpose Test(PPT-klausulen) i svenska skatteavtal kommer påverka den svenska hanteringen av missbruk av skatteavtalsbestämmelser. Eftersom PPT-klausulen, genom den Mulitlaterala konventionen för att motverka skat-teflykt, har införlivats i skatteavtalet mellan Sverige och Storbritannien, kommer analysen göras med The purpose of this paper is to examine and analyse how the introduction of the Principal Purpose Test (the PPT clause) in Swedish tax treaties will affect the Swedish handling of abuse of tax treaty provisions. Since the PPT clause, through the Multilateral Convention to Implement Tax Treaty Related Measures, has been incorporated into the tax treaty between Sweden and the United Kingdom, the ana
Historically, since its inception in the late 1930s, the album cover has been an important platform for visual creativity that has enabled creators such as artists, illustrators, photographers and designers to experiment with different styles and concepts. The democratization of art through the album cover aims to analyze how this form of artistic expression has and continues to contribute as a me
This study investigates how EPU affects stock returns and volatility for Sweden’s four largest banks: Swedbank, Skandinaviska Enskilda Banken, Svenska Handelsbanken, and Nordea. As a small open economy with a concentrated and globally exposed banking sector, Sweden is particularly vulnerable to both domestic and international uncertainty shocks. Using monthly data from 2000 to 2024, we apply a GAR
As populism becomes increasingly prominent in global politics, the academic literature presents socioeconomic factors as an underlying reason. This paper aims to find whether such factors can explain the increase in Republican support in Michigan during the time period of 2012 to 2024, with particular recognition of the role of Donald Trump as a populist candidate. Michigan has experienced notable
This thesis uses norm research and a developed theoretical framework to find the ‘climate policy norm’ that affects and creates the argumentation for the European Commission's climate policy measures, and puts it on the life cycle of norms for the years 2019 and 2024. Through a comparative discourse analysis and qualitative data study, this paper develops the theoretical understanding of norm
