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In 2024 the European Declaration of Cycling was signed as a tri-institutional declaration by the European Commission, Council of the European Union and the European Parliament. For the first time, cycling was acknowledged as a fully fledged mode of transport in a EU-level framework and through it, cycling now sits officially on the agenda of the EU. Yet this level of political attention was for ma
Species of the Mycobacterium avium complex display two main colony morphologies, smooth transparent (SmT) and smooth opaque (SmO), where SmT is associated with human disease and antimicrobial resistance. Previous studies have suggested that smooth bacteria can reversibly switch between the transparent and opaque forms, but the mechanism underlying morphotype transition has remained unknown. Using
BACKGROUND/PURPOSE: Cytokines are essential for the prevention of microbial infections. Total parenteral nutrition (TPN) in infancy is associated with an increased risk of infection, and this could be related to altered cytokine production. The aim of the study was to determine if cytokine production is altered in monocytes from surgical infants receiving TPN. METHODS: There were 3 study groups: (
The argument and discussion in this paper begins from the premise that Hume was an atheist who denied the religious or theist hypothesis. However, even if it is agreed that that Hume was an atheist this does not tell us where he stood on the question concerning the value of religion. Some atheists, such as Spinoza, have argued that society needs to maintain and preserve a form of “true religion”,
A vibronic exciton model is applied to explain the long-lived oscillatory features in the two-dimensional (2D) electronic spectra of the Fenna-Matthews-Olson (FMO) complex. Using experimentally determined parameters and uncorrelated site energy fluctuations, the model predicts oscillations with dephasing times of 1.3 ps at 77 K, which is in a good agreement with the experimental results. These lon
Overweight and obesity among children has gained increased attention as one of the most unequally distributed health problems. This article draws on interviews with school nurses, who in their daily work handle this problem. Their responses articulate a discrepancy between the general view on overweight and obesity as a “disaster” for the afflicted children and the practice of turning "a blind eye
To define the clinical presentation of aerococcal infective endocarditis (IE) and the prevalence of synergy between penicillin and gentamicin on aerococcal isolates.
The addition of amphiphiles grafted with polyethylene glycol units to constructs of DNA-amphiphiles is of most relevance for applications demanding colloidal stability. In this work, we study the self-assembly behavior of a true ternary mixture comprising (i) an electroneutral complex of DNA and a cationic surfactant (dodecyltrimethylammonium, DTA), (ii) water, and (iii) nonionic surfactant (dodec
T cells are crucial players in cell-mediated immunity. The specificity of their receptor, the T cell receptor (TCR), is central for the immune system to distinguish foreign from host antigens. Superantigens are bacterial toxins capable of inducing a toxic immune response by cross-linking the TCR and the major histocompatibility complex (MHC) class II and circumventing the antigen specificity. Here
A new two-state polymer folding model is proposed, in which the folding of a stiff helical polymer is enabled by allowing for short sequences of coils connecting shorter and separated helices. The folding is driven by short-range attraction energy among stacked helices and is opposed by the free-energy cost of forming coils from helical monomers. Principal outcomes of the model are equilibrium dis
There is a notable research gap in understanding the differential impacts of transnational versus domestic agricultural large-scale land acquisitions (LSLAs) on local biodiversity. This thesis addresses this gap within the context of Latin America and the Caribbean. Utilizing spatial panel datasets of the Biodiversity Habitat Index (BHI) from 2000 to 2020, LSLA area approximations, and a diverse s
Purpose – This study explores the underlying motives of individuals who have decided to stop flying for environmental reasons – hereinafter the non-flyers. We address this as an anti-consumption phenomenon that has increased traction in recent years due to the ever-increasing concern around environmental issues and their implications for the well-being of societies and the planet. In doing so, we
To understand the mechanisms of economic resilience, we have studied how sectoral proximity relates to the regional capability to transform and recover from a shrinking crisis. Through a comparative study of Irish regions, a proximity analysis provided evidence that the majority of new sectors in the recovering region developed in proximity to the region’s leading sector. This leads to the conclus
This thesis has examined if there is any difference in the relationship between different risk factors and the cross-section of assets excess returns on the Swedish stock market between days when macroeconomic news is scheduled to be announced (announcement days) and other days (normal days). The Fama and Macbeth two-pass regression method have been used for investigating the hypothesis that annou
Phantoms mimicking the specific mechanical and acoustic properties of human tissues are essential in the development and evaluation of novel ultrasound methods. In this work, various ultrasound phantoms are proposed to be used in the development of ultrasound methods to investigate the arterial walls longitudinal movements influence on the vasa vasorum circulation. The longitudinal movement of art