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Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LTBI testing was performed by quantification of interferon-γ
Background: Fluid resuscitation after uncontrolled hemorrhage might promote rebleeding and irreversible shock. Tranexamic acid is a procoagulant drug that limits blood loss after surgery of the hip, knee, and heart. We hypothesized that pretreatment with tranexamic acid reduces the rebleeding in uncontrolled hemorrhage and thereby allows safe administration of crystalloid fluid resuscitation.Metho
The argument and discussion in this paper begins from the premise that Hume was an atheist who denied the religious or theist hypothesis. However, even if it is agreed that that Hume was an atheist this does not tell us where he stood on the question concerning the value of religion. Some atheists, such as Spinoza, have argued that society needs to maintain and preserve a form of “true religion”,
Homelessness is a growing global problem. Homelessness produces and reinforces social exclusion. The main reason for homelessness is that there is a shortage of housing available to people with low incomes. Counteracting homelessness requires housing policy initiatives that make it possible for people with low incomes to have access to housing. At the same time people who are homeless must receive
Austrian artist and director of ZKM Center for Art and Media in Karlsruhe, Germany, Peter Weibel (Odessa, 1944), curates a book/catalogue of the mythical exhibition Sound Art, Sound as Medium of Art, that took place between March 2012 and February 2013 in Karlsruhe, with nearly one thousand images of sound art pieces. Along with a very detailed historical trace of sound as a form of art, the book
CONTEXT: The natural course of HIV disease progression among resource-poor patient populations has not been clearly defined.OBJECTIVE: To describe predictors of HIV disease progression as seen at an outpatient clinic in a resource-limited setting in rural Ethiopia.DESIGN: This prospective cohort study included all adult HIV patients who visited an outpatient clinic at Arba Minch hospital in South
We study the problem of distance-based formation shape control for autonomous agents with double-integrator dynamics. Our considerations are focused on exponential stability properties. For second-order formation systems under the standard gradient-based control law, we prove local exponential stability with respect to the total energy by applying Chetaev's trick to the Lyapunov candidate function
I antologin är kapitel samlade som ut olika perspektiv behandlar undervisning och lärande i musik samt musiklärares professionsutveckling. Karl Asp problematiserar genrebegreppet och exemplifierar hur det är möjligt att planera sin musikundervisning utifrån resonemang om vad genre kan tänkas vara och innebära. Konsekvenser av genrer och de praktiker som kan uppstå i ensembleundervisning när det gä
Asset integrity and management is an important part of the oil and gas industry especially for existing offshore structures. With declining oil price, the production rate is an important factor to be maintained that makes integrity of the structures one of the main concerns. Reliability based and risk- based inspection (RRBI) constitutes an efficient method to optimize inspection planning. Basing
This paper focuses on a reliability analysis of an offshore wind turbine support structure which is part of an assessment and monitoring framework for wind turbines in operation. The reliability analysis builds upon structural, loading, limit state and uncertainty models comprising design, production and erection data. This model basis facilitates the reliability analysis of the ultimate, the fati
The individual failure of nation states to combat crime (in particular transnational crime) has led to the adoption of international, regional and bilateral legal frameworks for police and judicial cooperation in criminal matters between states. It is widely recognized that transnational criminal activities weaken the ability of states to maintain security within their own boundaries. Yet whilst t
The dynamical formation of black hole binaries in globular clusters that merge due to gravitational waves occurs more frequently in higher stellar density. Meanwhile, the probability to form intermediate mass black holes (IMBHs) also increases with the density. To explore the impact of the formation and growth of IMBHs on the population of stellar mass black hole binaries from globular clusters, w
Questions concerning the occurrence of adaptive sex ratio manipulation have a long research tradition in evolutionary biology, but evidence from birds is scarce. It has been suggested that birds are unable to adaptively determine the sex of their young because of the constraints of their sex determination systems. Here we report results from a study of variation in offspring sex ratio in the blue
The stiffness assessment of the trackbed should include an assessment of ballast, subballast and formation (e.g sub-ballast depth, groundwater profile). Furthermore, a lack of a systematic monitoring brings to the impossibility to produce an effective long term track management system, by allocating budget where emergencies come. Consequently, there is an increasing importance in obtaining a consi
The influence of wind is only occasionally accounted for in fire safety engineering, still the effect of wind on, for example, the performance of a smoke management system can be large. A simple analytical method to account for the effect of wind on mass flow through horizontal openings for natural ventilation is compared to results from CFD simulations in this paper. It is seen that the correspon
The kinetics of enzymatic conversion in a microemulsion have been investigated. Racemic 3-methylcyclohexanone was oxidized by horse-liver alcohol dehydrogenase (HLADH, E.C. 1.1.1.1.) using a coupled substrate-coenzyme regenerating cycle in a sodium bis-(2-ethylhexyl) sulphosuccinate (AOT)-isooctane-buffer microemulsion. Initial enzyme activity was measured as a function of the oil volume fraction
Viral infections predispose to the development of childhood asthma, a disease associated with increased lung mast cells (MCs). This study investigated whether viral lower respiratory tract infections (LRTIs) can already evoke a MC response during childhood. Lung tissue from young children who died following LRTIs were processed for immunohistochemical identification of MCs. Children who died from
