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Our research uses advanced technology to generate neurons from novel cell sources with the aim to extensively define the subtype and function of the generated neurons and their potential for therapeutic use in the future. For this we are using reprogramming technology in animal models or human stem cell culture system, together with electrophysiology, RNA sequencing, tracing technologies and cell
Forskargruppen "Barninfektioner och global barn- och ungdomshälsa" främjar forskning och utbildning. Det primära forskningsområdet är pediatrik och mer specifika inom området barninfektioner, Kawasakis sjukdom, global barn och -ungdomshälsa samt migration. Forskargruppen samarbetar med andra forskargrupper både nationellt och internationellt. Forskargruppen är involverad i utbildningen av läkarsPediatric infectious diseases and global child health is a research group promoting high quality research and education. The primary area of research is Pediatrics and more specific in the field of infectious diseases, Kawasaki disease, global child health and migration. The research group collaborates with research teams both nationally and internationally as well as being involved in the educa
I världen lider flera 100 miljoner människor av autoimmuna sjukdomar och de är ett folkhälsoproblem i paritet med cancer och hjärt/kärlsjukdomar. Vi har fokuserat vår forskning kring en grupp ovanliga men allvarliga autoimmuna sjukdomar, ANCA associerade vaskuliter. Sjukdomarna orsakar en akut inflammation i de små blodkärlen, vilket leder till en snabbt förlöpande glomerulonefrit och livshotande Autoimmune diseases affect several 100 million people world wide and is a tremendous public health problem comparable with heart disease and cancer. We have focused our research to a group of severe autoimmune diseases, called ANCA (anti-neutrophil cytoplasmic antibody) associated systemic vasculitis. The diseases present with acute inflammation in the small vessels and cause rapidly progressive r
The field of research is to uncover the genetic and environmental etiology of autoimmune (type 1) diabetes, celiac disease as well as narcolepsy. The genetics of the disease is dissected also in the spontaneously diabetic BB rat. Specific autoantibody markers are used to predict the clinical onset of diabetes or celiac disease. Longitudinal studies of children at increased risk allow studies of t
Bacterial infections spanning from local wound infections, affecting patients with non-healing leg ulcers, postoperative wounds or burns, to severe infections and sepsis, are significant medical problems. Today's anti-infective treatments do not address the excessive activation of inflammatory pathways during infection and sepsis, and resistance problems are increasing. Hence, there is a huge unm
Avdelningen för molekylär hematologi omfattar idag tolv forskningsgrupper som alla studerar olika aspekter av blodcellers funktion vid hälsa och sjukdom. Genom hela livet utgår all blodbildning från så kallade blodstamceller som försörjer kroppen med miljarder blodkroppar varje dag. En normal balanserad produktion av blodkroppar via blodstamcellerna är avgörande för att vi skall hålla oss friska.Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in ord
BioMS is the national infrastructure for biological mass spectrometry (MS). BioMS offers access to qualified projects in proteogenomics, targeted protein quantitation, glycoproteomics, hydrogen-deuterium exchange MS, glycomics, lipidomics, and chemical proteomics. Detailed information and the project application forms can be found at www.bioms.se. BioMS is hosted by Lund University with support fr
Sweden's ATMP ecosystem is rapidly expanding, solidifying its place as a key player in Europe. Currently ranking among the top three countries among the EU9 for identified therapeutic ATMP companies, Sweden's strategic investments are further reinforcing its leadership (MSC 2020). This includes ongoing initiatives to establish industrial-scale ATMP manufacturing capabilities, enhancing the country
Vid Kärlsektionen, Verksamhetsområde Thorax-Kärl, bedriver kärlkirurger, kärlmedicinare (angiologer), radiologer och sjuksköterskor både kvantitativ och kvalitativ, tvärprofessionell och experimentell forskning med fokus främst på sjukdomar i aorta, mesenterial-, karotis- och benartärer samt venös tromboembolism. Integrationen av kärlkirurger och kärlmedicinare ger sektionen en ledande position iAt Vascular Centre, Department of Cardio-Thoracic and Vascular Surgery, vascular surgeons, vascular physicians, radiologists and nurses are committed to quantitative and qualitative, multidisciplinary and experimental research with focus on diseases of the aorta, mesenteric, carotid and lower limb arteries, and venous thromboembolism. The integration of vascular surgeons and vascular physicians g
In diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflec
I ett samarbetsnätverk av svenska och internationella forskare är vår målsättning att mäta, individualisera och förbättra behandlingsresultat och hälsa hos personer med psykiska störningar. Vi fokuserar på patienternas egenbedömningar, utveckling av självskattningsskalor & applikationer samt kliniskt relevanta biologiska markörer. Ett projekt syftar till att undersöka effekten av livsstilsintervenIn a collaborative network of Swedish & international researchers, our aim is to measure, individualize and improve treatment outcomes and health in individuals with psychiatric disorders. We focus on patients' own assessments, the development of self-rating scales & applications, and clinically relevant biological markers. One project aims to investigate the effect of lifestyle intervention on me
Vår forskning handlar om att kartlägga de mekanismer som ligger bakom njursjukdom för att ta fram ny diagnostik och behandling för de cirka 10% av Sveriges befolkning som lider av nedsatt njurfunktion. Vi forskar också fram nya metoder för att förbättra behandlingen med så kallad peritonealdialys (bukdialys) - en form av dialysbehandling för patienter med svår njursvikt. Vi samarbetar med andra foOur research focuses on identifying the mechanisms behind kidney disease in order to develop new diagnostic methods and treatment for the approximately 10% of Sweden's population suffering from impaired renal function. We are also researching new methods to improve treatment with peritoneal dialysis - a form of dialysis treatment for patients with severe renal failure. We collaborate with other re
Vår grupp bedriver forskning med fokus på psykiatri, utveckling och aggressivt, antisocialt beteende i ett livsloppsperspektiv. Huvuddelen av våra projekt är kliniska och longitudinella och undersöker riskfaktorer för och utvecklingen av utagerande beteende samt psykisk ohälsa, funktionsnedsättningar, neurokognitiva problem, somatiska sjukdomar, social utsatthet, problem i skolan och på arbetsmarkOur group conducts research related to mental disorders, development and aggressive, antisocial behaviour. We focus on clinical longitudinal studies on the development and course of externalizing behaviour and concomitant disorders and problems such as psychiatric and somatic disorders, neurodevelopmental disorders, neurocognitive functioning, social and educational problems, from early childhood
