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The haematopoietic hormone erythropoietin (EPO) has neuroprotective properties and is currently being explored for treatment of stroke and other neurological disorders. Short-term, high-dose treatment with EPO seems to improve neurological function of stroke patients but may be associated with increased thrombotic risk, whereas alternative non-erythropoietic neuroprotective derivatives of EPO, suc
Background: There is a lack of standardisation in quality of life (QoL) measurements to be used in older multimorbid patients. An ideal QoL measurement should be reliable, valid, subjective, multidimensional, feasible and generic. We hypothesised that the QoL-AD (Quality of Life in Alzheimer's Disease) scale could have these properties. Our aim was to determine the psychometric properties and clin
Mouse plasmacytomas (MPCs) induced by pristane oil, or by a combination of pristane oil and Abelson virus, carry one of two chromosomal translocations. The typical 12; 15 translocation leads to the juxtaposition of c-myc and immunoglobulin heavy-chain sequences, whereas the 6; 15 translocation links the kappa light-chain locus with the pvt-1 (plasmacytoma variant translocation) locus, located at l
Sweden is widely considered to have one of the most equal and gender-equal societies in the world. But the Swedish society is also one in which the Labour Court can find discrimination when a 60-year-old ‘Swedish’ ‘white’ woman fails to get a job interview – yet not when workers call a colleague of Gambian background ‘blackie’, ‘big black bastard’, ‘the African’, and ‘svartskalle’, or a man of Nig
Rural law courts are sometimes believed to have contributed to juridical fragmentation, which led to coordination failures and, hence, to high transaction costs. We present a case study of the village law court of Mijnsheerenland, and pay particular attention to the question of whether non-residents expected villagers to have a 'home court' advantage. Our analysis of default risk premiums demanded
Background: Neurogenic inflammation has for decades been considered an important part of migraine pathophysiology. In the present study, we asked the question if administration of a novel kynurenic acid analogue (SZR72), precursor of an excitotoxin antagonist and anti-inflammatory substance, can modify the neurogenic inflammatory response in the trigeminal ganglion. Methods: Inflammation in the tr
The peroxisome proliferator-activated receptor gamma (PPARgamma), a member of the nuclear hormone receptor superfamily, is essential for adipocyte differentiation and glucose homeostasis. PPARgamma has been found recently to regulate macrophage activation in response to mitogens and inflammation. Our study shows PPARgamma to be preferentially expressed in the nuclei of resting T cells and to incre
A typical obstacle to cancer therapy is the limited distribution of low molecular weight anticancer drugs within the carcinoma tissue. In experimental carcinoma, imatinib (STI571) increases efficacy of synchronized chemotherapy, reduces tumor interstitial fluid pressure, and increases interstitial fluid volume. STI571 also increases the water-perfusable fraction in metastases from human colorectal
Objective: To describe the longitudinal patterns of release, and investigate the association between a set of synovial fluid biomarkers at the acute and chronic stage and the development of radiographic knee osteoarthritis (OA) after an anterior cruciate ligament (ACL) injury. Design: Synovial fluid was aspirated from the acutely ACL-injured knee within the first 2weeks (acute samples), and yearly
Introduction: This study was aimed to determine the association between PSA levels and biomarkers of subclinical systemic inflammation based on data from 119 middle-aged healthy men from the general population. Materials and Methods: Serum levels of PSA and biomarkers of systemic inflammation (CRP and fibrinogen) were measured. Demographic data were also collected. Subjects were divided into two g
Oxygen is known to play an important role in the multiferroicity of rare earth manganites; however, how this role changes with rare earth elements is still not fully understood. To address this question, we have used resonant soft x-ray scattering spectroscopy to study the F-type (0,τ,0) diffraction peak from the antiferromagnetic order in DyMnO3 and TbMnO3. We focus on the measurements at O K edg
Abstract This paper's objective is to bring context and important findings on how foreign direct investments can impact Sub Saharan Africa. Based on previous research and theory data has been collected and gone through several econometric tests to set up two different panel datas: 1. How FDI can impact CO2 emissions. 2. How FDI can impact corruption. The method of this study is designed so
This thesis addresses the ongoing debate on the involvement of Chinese nationals in Ghana's artisanal and small-scale gold mining (ASGM) sector. Despite the Minerals and Mining Law, Act 703 (2006) prohibiting foreigners from engaging in ASGM, it is reported that about 50,000 Chinese nationals have migrated to rural Ghana to engage in illegal mining activities. This has caught the attention of
The Swedish integration policies rely heavily on the establishment program, a measure taken as a consequence of the high unemployment rate among refugees after the “refugee crisis”. The establishment program aims to tackle the gap in access to the labour market between native-born and refugees through economic imperatives. Civil society organizations step in to provide programs that target refugee
Purpose: This paper explores the phenomenon of intra-portfolio co-branding in a house of brands and examines how co-branding partnerships increase brand equity and strengthen both the participating brands and the corporate portfolio. It also derives actionable guidelines on how to leverage such synergies. Methodology: A qualitative study based on secondary data, using case studies of Dior by Birke
This thesis examines the effects of European Union integration on exports, focusing on the most recent EU enlargement involving Croatia. In addition to assessing the direct impact of EU accession on Croatian exports to the EU, the study investigates potential spillover effects on exports from the Western Balkan Six (WB6) countries relative to a control group. The empirical strategy combines fixed-
Title: Leveraging Parent Company Resources in the Construction Industry: A Comparative Study of Internal Corporate Ventures and Independent Ventures Seminar date: 14 january, 2025 Course: FEKH99, Bachelor Degree Project in Entrepreneurship and Innovation Management, Business administration, Undergraduate level, 15 University Credit Points Authors: Noah Malmgren and Oscar Larsson Advisor/s: Joakim
This thesis explores the discursive elements and practices of the activist community resisting the construction of the 17th extension of the A100 Highway in eastern Berlin. Focusing on linguistic strategies, rhetorical devices and methods of activism employed by actors opposing the highway project, this study utilises a combination of Manuel Castells’ Urban Social Movement Theory and Norman Faircl
