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Bral1, a brain-specific hyaluronan-binding protein, has been cloned recently. To gain insight into the role of Bral1, we generated a specific antibody against this protein. We have examined the detailed localization pattern of Bral1 protein and compared it with that of other members of the lectican proteoglycan family, such as brevican and versican, with which Bral1 is predicted to interact. The i

Purpose To collect data for the development of a more universally useful logistic regression model to distinguish between a malignant and benign adnexal tumor before surgery. Patients and Methods Patients had at least one persistent mass. More than 50 clinical and sonographic end points were defined and recorded for analysis. The outcome measure was the histologic classification of excised tissues

It is argued that the Achilles heel of contemporary sociology – and great parts of social science – is a) weak theory development, and b) absence of a meta-theory providing a common platform and a shared goal for its practitioners, fostering cumulativity. A meta-theory called causal realism (a variant of critical realism) is suggested for these purposes. The main tenets and key concepts of realism

Purpose: Conventionally, the management of exocrine pancreatic insufficiency (EPI) involves the consumption of a specific diet as well as the replacement of pancreatic enzymes, the effectiveness of which is usually measured by a classical method of blood analyses of non-esterified fatty acids (NEFA) and triglycerides (TG). Dietary supplementation with a pancreatic enzyme preparation (PEP), in conj

We have examined the expression and activity of inducible nitric oxide synthase ( iNOS) and the activity of neuronal constitutive NOS ( ncNOS) in isolated rat pancreatic islets, stimulated by a "hyperglycaemic" concentration of glucose, and whether the NOS activities could be modulated by activation of the cyclic AMP/ protein kinase A ( cyclic AMP/PKA) system in relation to the insulin secretory p

Datakommunikation och nätverk ger en heltäckande och lättillgänglig redogörelse av modern datakommunikation. Boken är ett alternativ till internationella textböcker i ämnet, innehållet speglar kunskapsbehovet hos yrkesverksamma ingenjörer och ger de kunskaper som krävs på ett pedagogiskt och kärnfullt sätt. Boken innehåller förutom övningar även lästips och hänvisningar för den som vill söka fördj

Based on experiences and research presented during the WBLE 2nd 2001 (Web Based Learning Environment) conference on e-Learning at Lund University, Sweden, October 2001, one wish to obtain a glimpse into the status and future of e-Learning. During the conference a large number of worldwide research, experiences and dreams were presented. Thus, this conference gives us a good idea of the status toda

Recently, there has been a rise of contributions in innovation and economic geography studies on how firms from specific industries and regional innovation systems (RISs) rely on international networks to innovate. So far, the focus has been on single cases, firms located in well-known RISs and international linkages, without really distinguishing those with geographically close partners from thos

Two dolerite dyke swarms are recognized along and paralleling the Ural Mountains, Russia. The Uralian swarm is 1400-km long (2300-km long if traced from its inferred plume centre). Further north, the Pay-Khoy swarm can be traced through the Pay-Khoy–Novaya Zemlya fold belt for a distance of c. 250 km (800-km long if traced from its inferred plume centre). An Upper Devonian age for volcanism associ

Since the 1980’s, additive manufacturing (AM) has gradually advanced from rapid prototyping applications towards fabricating end consumer products. Many small companies may prefer accessing AM technologies through service providers offering production services as result-oriented Industrial Product-Service System (IPSS) rather than investing in their own production line. This study investigated pot

Purpose: To compare the earliest detection of progression in visual fields and monoscopic optic disc photographs at different stages of manifest glaucoma. Methods: This study evaluated 306 eyes in 249 patients with manifest open-angle glaucoma included in the Early Manifest Glaucoma Trial (EMGT). All patients in the trial were followed up regularly by standard automated perimetry and monoscopic op

Employing a socio-legal approach that draws on Bourdieuian studies of law, this study critically examines self-determination’s status as a norm of international activity by tracing the manner in which it has been articulated and transformed by a number of key actors, the empirical and theoretical tensions accompanying its trajectory, and the negotiations and interactive contestations that lie outs

OBJECTIVES: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015.METHODS: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respir

Rare inherited bleeding disorders (IBD) are a common cause of bleeding tendency. To ensure a correct diagnosis, specialized laboratory analyses are necessary. This study reports the results of an upfront diagnostic strategy using targeted whole exome sequencing. In total, 156 patients with a significant bleeding assessment tool score participated in the study, of which a third had thrombocytopenia

Deciphering the metamorphic evolution of the roots of mountain belts is essential for understanding deep tectonic processes involved in mountain building. The Sveconorwegian orogen in southwestern Scandinavia, formed during the Rodinia assembly in the transition between the Mesoproterozoic and Neoproterozoic Eras, has been exhumed and provides access to interior deep structural levels of the ancie

The hot erosion of turbine tip and the maintenance of tip reliability and service times have always been great challenges for researchers. This work presents a novel design of a tip wall with the internal surface fitted with delta-winglet vortex generator pairs (DVGP). Various spacing of DVGP is considered to study the influence of spacing on the internal tip heat transfer and flow behavior in the