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Single nucleotide polymorphisms (SNPs) in various genes have been shown to associate with COPD, suggesting a role in disease pathogenesis. Sulfatase modifying factor (SUMF1) is a key modifier in connective tissue remodelling, and we have shown previously that several SNPs in SUMF1 are associated with COPD. The aim of this study was to investigate the association between SUMF1 SNPs and advanced
We study selection into lab experiments based on data from two cohorts of first-year university students. We combine two experiments: a classroom experiment in which we elicit measures of time and risk preferences, overconfidence, trust, reciprocity, altruism, and cognitive reflection and a recruitment experiment with four treatment conditions that randomly vary the information provided in the e-m
We investigated the dissociation of dications and trications of three polycyclic aromatic hydrocarbons (PAHs), fluorene, phenanthrene, and pyrene. PAHs are a family of molecules ubiquitous in space and involved in much of the chemistry of the interstellar medium. In our experiments, ions are formed by interaction with 30.3 nm extreme ultraviolet (XUV) photons, and their velocity map images are rec
The European Union provides firm support to the maritime sector to reach the policy objectives in the Common Fisheries Policy. This paper analyzes to what extent the investment support to aquaculture and fish processing firms in Sweden increases firm investment activity. By doing so, the paper also quantifies the amount of investments that would have been undertaken also without support (deadweigh
Nanowire growth enables creation of embedded heterostructures, where one material is completely surrounded by another. Through materials-selective post-growth oxidation it is also possible to combine amorphous oxides and crystalline, e.g. III-V materials. Such oxide-embedded structures pose a challenge for compositional characterization through transmission electron microscopy since the materials
The pathway to forming the iron-rich planet Mercury remains mysterious. Its core makes up 70% of the planetary mass, which implies a significant enrichment of iron relative to silicates, while its mantle is strongly depleted in oxidised iron. The high core mass fraction is traditionally ascribed to evaporative loss of silicates, for example following a giant impact, but the high abundance of moder
X-ray microscopy is an essential imaging method in many scientific fields, which can be extended to three-dimensional (3D) using tomography. Recently, metal halide perovskite (MHP) nanomaterials have become a promising candidate for X-ray scintillators, due to their high light yield, high spatial resolution, and easy fabrication. Tomography requires many projections and therefore scintillators wit
Background and aim: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreparable scarring of lung tissue, with most patients succumbing rapidly after diagnosis. The mevalonate pathway, which is involved in the regulation of cell proliferation, survival, and motility, is targeted by the bisphosphonate zoledronic acid (ZA). The aim of this study was to assess the antifibroti
Hip fractures following a low-impact fall are common in the elderly. Finite element (FE) models of the proximal femur can improve the prediction of fracture risk over current clinical standards. Foramina in the femoral neck may influence its fracture mechanics, albeit the majority of FE modelling approaches do not consider them. This study aimed to show how foramina affect fracture propagation and
The case that constitutes the subject for this paper is a voluntourism project organized in the Faroe Islands that has gained worldwide attention. Unskilled volunteers were called to perform maintenance works while popular hiking trails remained closed for regular tourists. Thousands applied to build and mark trails in exchange for bed and board, while the idea was a successful marketing campaign
Background: Obesity seems to be associated with a poorer response to adjuvant chemotherapy in breast cancer (BC); however, associations in the neoadjuvant chemotherapy (NACT) setting and according to menopausal status are less studied. This study aims to investigate the association between pretreatment body mass index (BMI) and pathological complete response (pCR) following NACT in BC according to
What if, in the encounter between the subject and the city, it is the buildings, the streets, the rooms that are moving and the human beings who are at a standstill? Inspired by the efforts of literary scholars and human geographers to apply a unified understanding of space and time to the study of the (fictional) city, this article employs an analysis centered on the figure of the elevator to exp
Introduction: Rates of delivery by cesarean section have gradually risen in many parts of the world, and it is regarded as a safe surgical procedure with expanded indications. We assessed maternal complications within 6 weeks postpartum after planned cesarean section and after planned vaginal delivery among patients without medical indication for cesarean section. Material and methods: This was a
This study explored the relationship between the glucose dose and insulin response from beta cells in vivo and in vitro in mice. Glucose was administered intravenously at different dose levels (from 0 to 0.75 g/kg) in anesthetized C57BL/6J mice, and the glucose and insulin concentrations were determined in samples taken after 50 min. Furthermore, freshly isolated mouse islets were incubated for 60
The electoral success of radical right parties throughout Western Europe is the biggest change to these formerly stable party systems. Several studies have identified that mainstream parties can shape the trajectory of radical right parties. Our aim is to contribute to this literature, and to investigate if and how radical right parties gain from mainstream party recognition. Theoretically, we dra
Objectives: To investigate the association of exposure to per- and polyfluoroalkyl substances (PFAS) during early pregnancy with markers of the maternal thyroid system. Methods: Serum concentrations of seven PFAS as well as thyroid stimulating hormone (TSH), free and total thyroxine (FT4 and TT4), free and total triiodothyronine (FT3 and TT3) were measured in pregnant women in early pregnancy in t
Objective: To gain knowledge of underlying risk factors for vascular complications and their impact on life expectancy in myelofibrosis. Methods: From a cohort of 392 myelofibrosis patients registered in the Swedish MPN registry 58 patients with vascular complications during follow-up were identified. Patients with vascular complications were compared with both 1:1 matched controls and the entire
