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Background: Improvement in the surgical system requires intersectoral coordination. To achieve this, the development of National Surgical, Obstetric, and Anaesthesia Plans (NSOAPS) has been recommended. One of the first steps of NSOAP development is situational analysis. On the ground situational analyses can be resource intensive and often duplicative. In 2016, the Ministry of Health of Tanzania
Standard price indices may not account for the price decrease that results when patients switch to pharmaceutical products for which their demand-reservation price exceeds the price of the new product. In a similar way, standard price indices may not account for the price increase that results when patients switch to pharmaceuticals for which the reservation price is below the price of the new dru
BACKGROUND: Club foot is a common congenital deformity affecting 150 000-200 000 children every year. Untreated patients end up walking on the side or back of the affected foot, with severe social and economic consequences. Club foot is highly treatable by the Ponseti method, a non-invasive technique that has been described as highly suitable for use in resource-limited settings. To date, there ha
Detecting fires at an early stage is crucial for mitigating and extinguishing fires. The increased use of biofuels in Northern Europe has led to an increased number of fires in storage facilities. These fires are often caused by self-heating in the interior of the stored materials and slowly develop to smouldering fires. Consequently, these smouldering fires are usually detected several days or we
We have studied the thermodynamics of oxide formation, and the recovery of silicon and the metal catalysts from the dissociation of their respective oxides during the growth process of Si nanowires (NWs) under the Vapor → Liquid Droplet → Solid (VLS) mechanism. It is demonstrated that Si NWs under growth temperatures are thermodynamically unstable in any gas phase containing even a small concentra
Regulation of therapeutic transgene expression can increase the safety of gene therapy interventions, especially when targeting critical organs such as the brain. Although several gene expression systems have been described, none of the current systems has the required safety profile for clinical applications. Our group has previously adapted a system for novel gene regulation based on the destabi
För att bättre kunna förebygga att skelettet bryts ner vid långvarig vila eller vid sjukdomarsom osteopenia och osteoporos, behövs bättre förståelse för de processer somstyr detta. I den här avhandlingen antas att den primära orsaken till bentillväxt är enförändring i den kemiska miljön i benet. Förändringen antas orsakas av att tillväxtstimulerandeämnen transporteras genom benet till den plats däIn order to prevent or modify bone degeneration due to rest or due to diseases such as osteopenia and osteoporosis, the modeling and remodeling of bone tissue must be better understood. In this thesis it is assumed that the primary condition leading to bone growth is a change of the chemical environment caused by transport of matter resulting from stress driven diffusion. The change in the chemica
Sessions included an overview of past cell therapy (CT) conferences sponsored by the International Alliance for Biological Standardization (IABS). The sessions highlighted challenges in the field of human pluripotent stem cells (hPSCs) and also addressed specific points on manufacturing, bioanalytics and comparability, tumorigenicity testing, storage, and shipping. Panel discussions complemented t
The gene (xyn1) encoding a Rhodothermus marinus xylanase has been cloned and expressed in Escherichia coli. The gene comprises 5 different domains in an unusual combination. The cellulose binding domains (CBDs) encoded by xyn1 are repeated in tandem at the N-terminus and show similarity with the CBD family IV. The xyn1-gene is the first example encoding a CBD family IV in combination with a xylan
Future applications of internet of things (IoT) will go far beyond connecting sensors to the internet. The real challenge lies in how to easily build well working systems of things: well integrated distributed applications that support users, yet built from a variety of devices running on a variety of networks and protocols, and including services that were not designed to interoperate.Based on ou
Modern transportation requires advanced powertrain systems to reduce the production of greenhouse gas CO2. Partially premixed combustion (PPC) is one of the most promising methods to achieve low emission and low fuel consumption of internal combustion engines. The present paper evaluated the effects of the calibration parameters on the efficiency and emissions of a multi-cylinder engine using PPC
The NP-hard maximum rooted resolved triplets consistency problem (MRTC) takes as input a set [Formula presented] of leaf labels and a set [Formula presented] of resolved triplets over [Formula presented] and asks for a rooted phylogenetic tree that is consistent with the maximum number of elements in [Formula presented]. This article studies the approximability of a generalization of the problem c
This paper introduces a predictive combustion-engine controller for efficient fulfillment of constraints on peak pressure, exhaust temperature and NO emissions. The controller utilizes a in-cylinder pressure sensor, actuation of multiple fuel injections and numerical optimization. A physical model is used to predict pressure changes due to fuel-injection variation. The predicted pressure is used t
Partially premixed combustion (PPC) is a hybrid combustion of Homogeneous Charge Compression Ignition (HCCI) and Diesel Combustion (DC), which has a great potential in reducing the fuel consumption. PPC has a longer premixed time than DC but lesser than HCCI. Therefore it is more stratified than HCCI. This paper first presents results on how the stratification using multiple injections and differe
Purpose: The purpose of this study is to investigate the effects of human capital and relational trust on business-to-business (B2B) brand equity. Design/methodology/approach: Data collection was conducted among the clients of one of the Big Four auditing firms in Sweden. Structural equation modeling was used to test the hypothesized effects. Findings: The results demonstrate positive effects of h
Panic Disorder, with or without agoraphobia (PDA or PD, respectively), is a major public health problem. After having established a PD diagnosis based on the DSM or the ICD systems, the Panic Disorder Severity Scale (PDSS) is the most widely-used interview-based instrument for assessing disorder severity. There is also a self-report version of the instrument (PDSS-SR); both exist in a Swedish tran
Today plant-based alternatives to animal-agricultural products are made available or developed alongside ‘cultured’ meat, and products utilising genetic modification. To proponents, this signifies the emergence of ‘cellular agriculture’ as a food-production field or the possibility of a ‘post-animal bioeconomy’: a way to safely and sustainably produce animal products without animals. Drawing on pr
The outer layer of the skin, stratum corneum (SC) is an efficient transport barrier and it tolerates mechanical deformation. At physiological conditions, the majority of SC lipids are solid, while the presence of a small amount of fluid lipids is considered crucial for SC barrier and material properties. Here we use solid-state and diffusion nuclear magnetic resonance to characterize the compositi
