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Gluten protein crosslinking is a predetermined process where specific intra-and intermolecular disulfide bonds differ depending on the protein and cysteine motif. In this article, all-atom Monte Carlo simulations were used to understand the formation of disulfide bonds in gliadins and low molecular weight glutenin subunits (LMW-GS). The two intrinsically disordered proteins appeared to contain mos
The Taymyr Peninsula constitutes the eastern delimitation of a possible Kara Sea basin ice sheet. The existence of such an ice sheet during the last global glacial maximum (LGM), i.e. during the Late Weichselian/Upper Zyryansk, is favoured by some Russian scientists. However, a growing number of studies point towards a more minimalistic view concerning the areal extent of Late Weichselian/Upper Zy
Contamination of the water and sediment with per- and polyfluoroalkyl substances (PFAS) was studied for the lake impacted by the release of PFAS-containing aqueous film forming foam (AFFF). PFAS concentrations were analyzed in lake water and sediment core samples. ΣPFAS concentrations were in the range of 95-100 ng L-1 in the lake water and 3.0-61 µg kg-1 dry weight (dw) in sediment core samples,
We characterize a class of systems for which the H-infinity optimal control problem can be simplified in a way that enables sparse solutions and efficient computation. For a subclass of the systems, an optimal controller can be explicitly expressed in terms of the matrices of the system's state-space representation. In many applications, the controller given by this formula, which is st
In this paper, an adaptive design methodology for synthesizing a harmonic free N-path filter with reduced frequency folding is presented. System level analysis of proposed architecture shows that by adding a few extra paths with proper weights to a conventional N-path filter, several characteristics such as harmonic rejection, power reduction, foldback elimination and spectrum shaping can be achie
A novel method using the cloud to implement a variable horizon model predictive controller is presented. In case of sudden long delays and downtime, a graceful degradation is used. Robust, best effort strategies allow industrial grade use of the powerful, efficient, and quickly improving cloud ecosystems. The variable horizon strategy finds use in, for example, non-linear control problems, and the
A two-tier architecture for cloud-based MPC is presented consisting of a high rate MPC in the cloud and a low rate MPC on the local device. The system use the cloud MPC as the nominal controller but switches to local MPC in case of connectivity loss. The two MPCs are designed to be as similar to each other as possible except for the sampling rate. Different alternatives for when to execute the loc
In this article, the effects of convex dimple streamwise arrangements on the flow and heat transfer characteristics of protrusion-grooved channels are determined, and five streamwise positions of convex dimples are considered. In addition, research on the transverse-circular-protrusion-grooved channel is also performed to serve as a contrast. The results indicate that replacing the transverse-circ
Background and objective: New proposals to improve the regulation of hypnosis in anaesthesia based on the development of advanced control structures emerge continuously. However, a fair study to analyse the real benefits of these structures compared to simpler clinically validated PID-based solutions has not been presented so far. The main objective of this work is to analyse the performance limit
Deep learning has proven itself to be a powerful tool to develop datadriven signal processing algorithms for challenging engineering problems. By learning the key features and characteristics of the input signals instead of requiring a human to first identify and model them, learned algorithms can beat many human-made algorithms. In particular, deep neural networks are capable of learning the comp
Efficient unit propagation for clausal constraints is a core building block of conflict-driven clause learning (CDCL) Boolean satisfiability (SAT) and lazy clause generation constraint programming (CP) solvers. Conflict-driven pseudo-Boolean (PB) solvers extend the CDCL paradigm from clausal constraints to integer linear constraints, also known as (linear) PB constraints. For PB solvers, many diff
Background: Gout is predicted by a number of comorbidities and lifestyle factors. We aimed to identify discrete phenotype clusters of these factors in a Swedish population-based health survey. In these clusters, we calculated and compared the incidence and relative risk of gout. Methods: Cluster analyses were performed to group variables with close proximity and to obtain homogenous clusters of in
Intimate partner violence against women (IPVAW) poses severe threats to women’s health and rights. This study investigates the role of country context and gender equality in shaping individual perceptions of the severity of IPVAW. Multilevel logistic regression analyses of a Eurobarometer survey on attitudes toward IPVAW from 27 EU states showed that male gender, young age, low education, low self
We present a framework for measurement dimension reduction in Gaussian filtering, defined in terms of a linear operator acting on the measurement vector. This operator is optimized to minimize the Cramér-Rao bound of the estimate's mean squared error (MSE), yielding a measurement subspace from which elements minimally worsen the filter MSE performance, as compared to filtering with the original me
Event-based control is a promising concept for the design of resource-efficient feedback systems, where events such as sampling, actuation, and data transmissions are triggered reactively based on monitored control performance rather than a periodic timer. In this thesis, we investigate how sampling and communication events should be triggered to fully exploit the potential of event-based control
We propose a methodology for studying the performance of common splitting methods through semidefinite programming. We prove tightness of the methodology and demonstrate its value by presenting two applications of it. First, we use the methodology as a tool for computerassisted proofs to prove tight analytical contraction factors for Douglas-Rachford splitting that are likely too complicated for a
The implementation of multidisciplinary research approaches is an essential prerequisite to obtain comprehensive insights into the life and works of the old masters and their timeline in the production of the arts. In this study, traditional art history, cultural heritage, and natural science methods were combined to shed light on an Adoration of the Shepherds painting by Jacques Jordaens (1593–16
The Covid-19 pandemic has spawned numerous dynamic modeling attempts aimed at estimation, prediction, and ultimately control. The predictive power of these attempts has varied, and there remains a lack of consensus regarding the mechanisms of virus spread and the effectiveness of various non-pharmaceutical interventions that have been enforced regionally as well as nationally. Setting out in data
