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Hydrogen stands out as a compelling alternative to fossil fuels for combustion engines. Predictive combustion models are instrumental in developing hydrogen-fuelled engines. A fundamental metric of these models is the laminar burning velocity (LBV), which can be precisely determined through laminar flame propagation simulations. In this context, the selection of an appropriate combustion mechanism
In this study, a comprehensive investigation of a set of phytochemicals to identify potential inhibitors for the Forkhead box protein M1 (FOXM1) was conducted. FOXM1 is overexpressed in glioblastoma (GBM) cells and plays a crucial role in cell cycle progression, proliferation, and invasion. FOXM1 inhibitors have shown promising results in preclinical studies, and ongoing clinical trials are assess
Cork oak and pine bark, two of the most prolific byproducts of the European forestry sector, were assessed as biosorbents for eliminating potentially toxic elements (PTEs) from water-based solutions. Our research suggests that bioadsorption stands out as a viable and environmental eco-friendly technology, presenting a sustainable method for the extraction of PTEs from polluted water sources. This
Purpose: Despite increasing focus among scholars and practitioners on the design of product-service systems (PSS), there exists no compilation of current knowledge on the role played by small and medium-sized enterprises (SMEs) in designing such systems. Thus, this paper sets out to identify and organise the existing research and suggest questions for future research. Design/methodology/approach:
Physiologically based pharmacokinetic (PBPK) models offer the ability to simulate and predict the biodistribution of radiopharmaceuticals and have the potential to enable individualised treatment planning in molecular radiotherapy. The objective of this study was to develop and implement a whole-body compartmental PBPK model for peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu-DOTA-TATE
Aim: Previous research has indicated that preoperative beta blocker therapy is associated with a decreased risk of complications after surgery for rectal cancer. This is thought to arise because of the anti-inflammatory activity of the drug. These results need to be reproduced and analyses extended to other drugs with such properties, as this information might be useful in clinical decision-making
Background: Histological grade is a well-known prognostic factor that is routinely assessed in breast tumours. However, manual assessment of Nottingham Histological Grade (NHG) has high inter-assessor and inter-laboratory variability, causing uncertainty in grade assignments. To address this challenge, we developed and validated a three-level NHG-like deep learning-based histological grade model (
The variations of atmospheric Δ14C over the past two millennia are classically attributed to changes in its production rate in the upper atmosphere, which in turn is related to changes in solar activity and the Earth's magnetic field. However, the potential contribution of atmospheric and oceanic circulation changes during this period has not been precisely quantified. This has been achieved here
Taking as the starting point the increasing interest for utilizing public procurement as a means to stimulate innovation, this paper explores some considerations for curriculum development for teaching public procurement of innovation. A basic understanding of what is a curriculum was used as a foundation for the development of a master level course in public procurement of innovation in a univers
In this paper, we propose a new methodology for optimal memory mapping of data and instructions to Scratch-Pad Memories (SPM). In the mapping process, we optimize, as the main priority, the number of memory accesses to minimize power consumption. Minimization of external memory accesses lowers switching activity and therefore power consumption. The optimization is done by finding Pareto-points, us
The traditional sheet metal forming process, including cast steel die tool and conventional work materials, is fairly well established and analysed. Developments of new alternative materials make great demands upon new forming processes and manufacturing methods. A general goal for the manufacturing industries is to reduce the weight of metal parts, reduce batch sizes and reduce the lead-time of n
The legal empowerment approach is a recent attempt to be specific about the role of institutions for the future eradication of poverty. This is a broad concept that includes not only the national formal judicial system in a country, but all formal and informal institutional structures providing the rules of the game of human interaction in any given society. It has invited a lot of debate as to wh
Power grids worldwide are expanding not only driven by ambitious clean energy, but also because of the rising need for reliable energy. Key components of these power grids are transformers. Transformers are traditionally filled with mineral oil, to serve as a coolant and dielectric insulator. Now globally a rising trend is observed towards the adoption of less flammable, biodegradable transformer
Public service eller radio och TV i allmänhetens tjänst kan betraktas som ett alltmer angeläget ämne att studera mot bakgrund av ett föränderligt medieklimat under intensiv konkurrens. Det bildar en central mediepolitisk fråga att balansera på såväl nationell som överstatlig nivå i förhållande till EU-rätten. I denna uppsats har en nutida förståelse för public service genom TV-sändningarna i allmäPublic service broadcasting can be considered as an increasingly important topic to study in the light of a changing media climate under intense competition. It also represents a central question in media policy to be balanced at a national as well as a supranational level in relation to EU law. In this thesis, an understanding of public service broadcasting with regard to television is based on
Cardiac magnetic resonance (CMR) images are used to investigate the heart for medical and research purposes. By injecting a contrast substance into the patient, myocardial infarctions (heart attacks) can be visualized in CMR image sets consisting of a number of image slices at different levels of the heart. Analysis of these images can detect an infarction, delineate it and estimate its size. This
Populärvetenskaplig sammanfattning Spektroskopi handlar om teoretiska modeller och experiment där man observerar ljus som har växelverkat med materia. Spektroskopiska metoder används inom många olika ämnesområden som exempelvis kemi, fysik och biologi. Ett jordnära exempel på tillämpad spektroskopi är människans öga. Reflekterat ljus från olika föremål samlas in av linsen i ögat, avbildas på näthiIn this thesis a novel spectroscopic method consisting of a combination of frequency domain photon migration (FPDM) and gas in scattering media absorption spectroscopy (GASMAS) is developed, for assessment of the mean optical path length and gas absorption in porous media. The system stability is experimentally investigated and measurements are performed on balsa and pine wood to evaluate the rela
