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Venous thromboembolism (VTE) is major health problem and is sometimes complicated by lethal pulmonary embolism (PE). Disturbances of the coagulation and anticoagulation systems are important risk factors for VTE. Comparative studies suggest that coagulation and innate immunity have a shared evolutionary origin. It is therefore unsurprising that the immune and coagulation systems are linked, with m
Vitamin K-dependent protein C is an important regulator of blood coagulation. After its activation on the endothelial cell surface by thrombin bound to thrombomodulin, it cleaves and inactivates procoagulant cofactors Va and VIIIa, protein S and intact factor V working as cofactors. Until recently, genetic defects of protein C or protein S were, together with antithrombin III deficiency, the estab
This study investigates volatility spillovers to electric power from large exogenous shocks in the prices of gas, coal, and carbon emission allowances in the German energy market. Our sample ranges from 2008 to 2016 and covers periods of different market conditions. We use a general VAR-BEKK model and the volatility impulse response function methodology to analyze and evaluate the spillover effect
It is well known that the xylem of gymnosperm trees consists mainly of tracheids and that the dimensions of these cells change over the growth season in temperate regions. When looking at a micrograph of a cross section of a growth ring, it can be seen that early in the season tracheids have larger radial diameters and thin walls, while tracheids formed later in the growth season have smaller radi
The causes and extent of regional inequality in the process of economic growth are at the core of historical economic research. So far, much attention has been devoted to studying the role of industrialization in driving regional divergence. But empirical studies on relatively unequal countries such as Italy or Spain show that inequality was already high when their modern industrialization began (
Today, between 8% and 16% of all individuals worldwide suffer from chronic kidney disease (CKD), which is becoming a growing public health issue. Creatinine and cystatin C are commonly used markers for kidney function, and estimated glomerular filtration rate (eGFR) and albuminuria are used to stage CKD. However, creatinine and eGFR are rather insensitive in identifying individuals at high risk of
Purpose – The purpose of this paper is to present recent empirical results concerning offshoring and backshoring of manufacturing from and to Sweden, to increase the understanding of manufacturing relocation in an international context. In particular, extent, geographies, type of production, drivers, and benefits of moving manufacturing in both directions are investigated. Design/methodology/appro
Appearance of l-DOPA-induced dyskinesia (LID) represents a major limitation in the pharmacological therapy with the dopamine precursor l-DOPA. Indeed, the vast majority of parkinsonian patients develop dyskinesia within 9–10 years of l-DOPA oral administration. This makes the discovery of new therapeutic strategies an important need. In the last decades, several animal models of Parkinson’s diseas
Boken behandlar den litauisk-amerikanske folkrättsjuristen, politikern, diplomaten och historikern Jacob Robinsons (1889-1977; på litauiska: Jokūbas Robinzonas) liv och verk i elva kapitel.
Neural networks designed for real-time object detectionhave recently improved significantly, but in practice, look-ing at only a single RGB image at the time may not be ideal.For example, when detecting objects in videos, a foregrounddetection algorithm can be used to obtain compact temporaldata, which can be fed into a neural network alongside RGBimages. We propose an approach for doing this, bas
The Twentieth Century in European Memory investigates contested and divisive memories of conflicts, world wars, dictatorship, genocide and mass killing. Focusing on the questions of transculturality and reception, the book looks at the ways in which such memories are being shared, debated and received by museum workers, artists, politicians and general audiences. Due to amplified mobility and comm
This paper presents a study of the role that photography of 14 October 1973 and 6 October 1976 has played in political mobilization around the two events. It is well known that in official archives limited versions of the events can be found. We must turn to alternative repositories (private homes, nonstates organisations, but also universities and libraries outside of Thailand) to find the antic
