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Background: FUS, EWS and TAF15 are structurally similar multifunctional proteins that were first discovered upon characterization of fusion oncogenes in human sarcomas and leukemias. The proteins belong to the FET ( previously TET) family of RNA-binding proteins and are implicated in central cellular processes such as regulation of gene expression, maintenance of genomic integrity and mRNA/microRN

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We report on experimental branching fractions (BFs) for 19 transitions from the three 3d 5( 6S)4s4p( 3P) y6P levels in Fe II, measured in Fourier transform spectra of a Penning discharge lamp and a hollow cathode lamp. The transition wavelengths span the interval between 1600 and 2850 Å. Absolute oscillator strengths ( f-values) have been derived by combining the BFs with experimental radiative li

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Popular Abstract in Swedish Hur förhåller sig ekonomisk tillväxt och fördelning till varandra när en ekonomi genomgår en strukturomvandlingsprocess? Denna klassiska frågeställning utgör det centrala problemet för denna avhandling. När Simon Kuznets i mitten av 1950-talet tog sig an samma fråga fann han med begränsade data att ekonomisk tillväxt förmodligen ökar inkomstklyftorna under en inledande What are the effects of growth on equality in a long-term perspective? What are the effects of different patterns of equality on subsequent growth? And why are these questions relevant for the understanding of economic development? These are the overriding questions posed in the dissertation. They are addressed in the context of long-term change from economic backwardness to modern economic growth

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Background: Traumatic brain injuries continue to be a significant cause of mortality and morbidity worldwide. Most traumatic brain injuries are classified as mild, with a low but not negligible risk of intracranial hemorrhage. To help physicians decide which patients might benefit from a computerized tomography (CT) of the head to rule out intracranial hemorrhage, several clinical decision rules h

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The sayings of the Desert Fathers had an important role in the monastic education and were very widespread. Originally written down in Greek, they were soon translated into all the main languages in the medieval Europe, and underwent transformations as they were copied. The sayings were organized in different ways, mainly alphabetically or according to themes, and as they were copied the repertoir

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The need for modelling of materials behaviour under various mechanical conditions is driven by the evolution of computer capacity and the ability of scientists to address complex mechanical problems. Reliable models for materials behaviour, including accurate numerical values of parameters, are necessary for a continued beneficial development of the computational side of solid mechanics. High rate

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The chapter analyses the obligation upon states to identify migrants as victims of harm falling within the scope of Article 4 ECHR and to extend protection and assistance to them as victims independently from any criminal proceedings and from any actual or potential participation by the victims in any criminal proceedings. More specifically, the questions under investigation are the following: Is

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The 1918 influenza pandemic had not only a massive instant death toll but also lasting effects on its survivors. Several studies have shown that children born in 1919, and thus exposed to the H1N1 virus in utero, experienced worse health and socioeconomic outcomes in older ages than surrounding birth cohorts. This study combines several sources of contemporary statistics with full-population indiv

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BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic concentrations has an intrinsic effect per se on cardiac repolarisation and the QT interval.METHODS:

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Background: Namibia has made significant gains in the fight against malaria, with a target of elimination by 2023. We examined the genotype and allele frequencies of glucose-6-phosphate dehydrogenase (G6PD) deficiency to inform decisions on primaquine use, as we recently detected clusters of Plasmodium ovale curtisi in Kavango. Methods: A multistaged cross-sectional sampling method was used to enr

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In this volume, the authors reflect on the question “what is socialism” as it pertains to today’s economy. There is particular emphasis on democratic socialism models as a potential alternative to classic authoritarian socialism. A number of topical questions are addressed such as: What is democratic socialism and is it feasible, or even viable? What can be learnt from existing democratic socialis

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Chest pain is one of the most common complaints at the emergency department (ED), and it is commonly the perceived likelihood of acute coronary syndrome (ACS) that drives management. Guidelines from the European Society of Cardiology (ESC) recommend the use of a 0-/1-h high-sensitivity cardiac troponin T (hs-cTnT) protocol to rule out or in ACS, but this is mostly based on observational studies. T

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Nappes of continental outer and outermost margin affinities (Middle Allochthon) were transported from locations west of the present Norwegian coast and thrust eastwards onto the Baltoscandian foreland basin and platform. They are of higher metamorphic grade than underlying thrust sheets and most are more penetratively deformed. These allochthons are treated here in three groups. The lower thrust s

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Artikeln undersöker eurons konsekvenser för integration och tillväxt i Östersjöregionen (Polen, Litauen, Lettland, Estland, Finland och Sverige). Efter Sovjetunionens sammanbrott har de baltiska staterna och Polen snabbt hämtat in på Västeuropa. Den globala finanskrisen blev ett kraftigt bakslag för de förra, men i mindre utsträckning för Polen. Penningpolitiken har gjort skillnad: den polska zlotWhich have been the consequences of the euro for integration and economic performance in the Baltic Sea region? After the collapse of the Soviet Union, the three Baltic states and Poland have been rapidly catching-up with Western Europe. The Great Recession becamea great setback for the former, while less so for Poland. A difference is the monetary policy: the Polish zloty depreciated in t

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U-Pb geochronology on baddeleyite is a powerful technique that can be applied effectively to chronostratigraphy. In southern Africa, the Kaapvaal Craton hosts a well-preserved Mesoarchean to Paleoproterozoic geological record, including the Neoarchean Ventersdorp Supergroup. It overlies the Witwatersrand Supergroup and its world-class gold deposits. The Ventersdorp Supergroup comprises the Klipriv

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Nine Ce ii lines have been identified and characterized within the spectral window observed by the Apache Point Observatory Galactic Evolution Experiment (APOGEE) survey (between λ1.51 and 1.69 μm). At solar metallicities, cerium is an element that is produced predominantly as a result of the slow capture of neutrons (the s-process) during asymptotic giant branch stellar evolution. The Ce ii lines

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This study examines the interdependence between research and development (R&D) resources, coopetitive performance, and extent of cooperation in development-related standardization settings that involve network effects. Coopetitive performance is measured as the firm’s influence on the change process of standards. Cooperation is measured as the number of firm technology partners in influencing

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The structural properties, and the intracrystalline swelling of Na+-, and Ca2+-montmorillonite (Na-, and Ca-mmt) have been investigated as an effect of decreasing the relative permittivity of the solvent, i.e. from water to ethanol (EtOH), utilizing the experimental techniques; small angle X-ray scattering (SAXS) and osmotic pressure measurements. The experimental data were compared with the conti