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Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 cases and 366,221 controls, we identify 35 MM risk loci, 12 of which are novel. Through functional fine-mapping and Mendelian randomization, we uncover two causal

Children's time investments in various activities may be important for reducing socioeconomic status (SES) gaps in educational and mental health outcomes. Using detailed time use diaries of Australian children aged 4–14, we observe that children from low SES backgrounds spend more time on digital media and less time on out-of-school enrichment activities, organised or for leisure. We explain the S

It has been established across several contexts that political attitudes are informed by heritable factors. However, it remains unclear how much of the stability we observe in political attitudes can be ascribed to environmental factors and how much of the stability is due to genetics. In this paper we show, using a unique three-wave panel dataset of twins (N = 2471) spanning ten years, that both

My written contribution responds to the questions: How des your practice relate to placemaking? How is it possible to use sense of place as material and starting point for research or artistic work? What methods do you use for co-creation and relationship building in relation to place?

Background: Transition from child-centered to adult-centered healthcare is a gradual process that addresses the medical, psychological, and educational needs of young people in the management of their autonomy in making decisions about their health and their future clinical assistance. This transfer is challenging across all chronic diseases but can be particularly arduous in rare neurological con

Background: Infants in the neonatal intensive care unit (NICU) are subjected to different types of stress, including sounds of high intensity. The sound levels in NICUs often exceed the maximum acceptable level recommended by the American Academy of Pediatrics, which is 45 decibels (dB). Hearing impairment is diagnosed in 2% to 10% of preterm infants compared to only 0.1% of the general paediatric

The paper examines how the increasing datafication of society and advancements in artificial intelligence (AI) offer new empirical opportunities to better understand the Minimum Content of Nationality (MCN). Despite the critical importance of the MCN in statelessness, it has largely been ignored in academic and policy circles. The ambiguity that results from this lack of engagement greatly complic

Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presen

To resolve the various types of biological ice nuclei (IN) with atmospheric models, an extension of the empirical parameterization (EP) is proposed to predict the active IN from multiple groups of primary biological aerosol particles (PBAPs). Our approach is to utilize coincident observations of PBAP sizes, concentrations, biological composition, and ice nucleating ability. The parameterization or

This paper explores the law and policy related to the identification, assessment, and recording of the statelessness of refugees in the Swedish asylum procedure. It considers the gaps in law and policy that can lead to a stateless refugee remaining in a prolonged, or potentially, indefinite stateless situation and the impacts of the temporary asylum law introduced in 2016. The temporary law can be

Case C-372/19 Belgische Vereniging van Auteurs, Componisten en Uitgevers CVBA (SABAM) v Weareone.World BVBA and Wecandance NV, Judgment of the Court of Justice of the European Union (Fifth Chamber) of 25 November 2020 The most recent excessive pricing case considered by Court of Justice of European Union (CJEU) revolved around fees imposed by a national royalty collective society (SABAM) on two Be

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

This book invites you to embark on a journey of discovery, where words become the palette for the expression of design. Furthermore, this book extends its utility to individuals working with Al and text-to-image creation. By enhancing the effectiveness of prompts, it empowers Al systems like Stable Diffusion, DALL-E, and MidJourney to produce refined and contextually relevant visual outputs. The t

During the Swedish-Russian Tundra Ecology -94 expedition one of the goals was to describe the local population fluctuations of Siberian lemmings over the Eurasian tundra. In order to compensate for the lack of repeated sampling, we used 4 different estimates to determine the phase position of the lemming populations at the different sites: i) the number of lemmings trapped per unit time; ii) the a

This Letter presents results from a combination of searches for Higgs boson pair production using 126-140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV recorded with the ATLAS detector. At 95% confidence level (CL), the upper limit on the production rate is 2.9 times the standard model (SM) prediction, with an expected limit of 2.4 assuming no Higgs boson pair production. Constraints

Context. The abundances of the α-elements are key for understanding the early chemical enrichment of the Galactic bulge. The elements of interest present lines in different wavelength regions, and some of them show lines only in part of the spectra. In the present work, the CNO trio, the a-elements Mg, Si, Ca, and Ti, and odd-Z Na and Al are examined as measured from optical and H-band lines. Aims

In this work we consider superconductor-semiconductor hybrids containing both trivial and Majorana zero modes and explore their signatures in the Majorana polarization. In particular, we consider trivial zero-energy states due to confinement and disorder, which seem to be very likely experimental scenarios. We show that the Majorana polarization is able to characterize the topological phase transi