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We examine the capacity of artificial biomolecular networks to respond to perturbations with structurally signed steady-state changes. We consider network architectures designed to balance their output production as a function of downstream demand: the species producing the output, called a source, up- or down-regulates its production rate as a function of the demand. Using an exact algorithm we s

We study diffusion of cooperation in a two-population game in continuous time. At each instant, the game involves two random individuals, one from each population. The game has the structure of a Prisoner's dilemma where each player can choose either to cooperate (c) or to defect (d), and is reframed within the field of approachability in two-player repeated game with vector payoffs. We turn the g

The clinical success of targeted cancer therapies is limited by the emergence of drug resistance often due to pre-existing tumor genetic heterogeneity and acquired, therapy-induced resistance. Targeted therapies have varied success in addressing metastatic disease, due to their ability to penetrate certain physiological compartments. This paper considers an evolutionary cancer model that incorpora

Estimating Cartesian contact forces and torques enables external force supervision for robotic manipulators and even force-controlled applications while avoiding the need for additional external sensing. Redundant manipulators facilitate the problem of Cartesian contact force and torque estimation (CCFE) at the TCP, since an increased amount of joint level information is available for estimating t

In many system identification methods, process model parameters are considered stochastic variables. Several methods do not only yield expectations of these, but in addition their variance, and sometimes higher moments. This paper proposes a method for robust synthesis of the proportional-integral-derivative (PID) controller, taking parametric process model uncertainty explicitly into account. The

In this paper we explain our concept of Interaction and Task Patterns, and discuss how such patterns can be applied to support mixed-initiative in symbiotic human-robot interaction both with service and industrial robotic systems.

The goal of the GHG-CCI project (http://www.esa-ghg-cci.org/) of ESA's Climate Change Initiative (CCI) is to generate global atmospheric satellite-derived carbon dioxide (CO2) and methane (CH4) data sets as needed to improve our understanding of the regional sources and sinks of these important greenhouse gases (GHG). Here we present an overview about the latest data set called Climate Research Da

This thesis addresses problems which require low-rank solutions under convex constraints. In particular, the focus lies on model reduction of positive systems, as well as finite dimensional optimization problems that are convex, apart from a low-rank constraint. Traditional model reduction techniques try to minimize the error between the original and the reduced system. Typically, the resulting re

Event-based sensing and communication holds the promise of lower resource utilization and/or better performance for remote state estimation applications found in e.g. networked control systems. Recently, stochastic event-triggering rules have been proposed as a means to avoid the complexity of the problem that normally arises in event-based estimator design. By using a scaled Gaussian function in

Large volumes of data from satellite sensors with high time-resolution exist today, e.g. Advanced Very High Resolution Radiometer (AVHRR) and Moderate Resolution Imaging Spectroradiometer (MODIS), calling for efficient data processing methods. TIMESAT is a free software package for processing satellite time-series data in order to investigate problems related to global change and monitoring of veg

Carbon dioxide (CO 2) is the most important anthropogenic greenhouse gas contributing to about half of the total anthropogenic change in the Earth's radiation budget. And about half of the anthropogenic CO2 emissions stay in the atmosphere, the remainder is taken up by the biosphere. It is of paramount importance to better understand CO2 sources and sinks and their spatio-temporal distribution. In

In this paper, we propose a soft-output detector for multiple-input multiple-output (MIMO) channels that utilizes achievable information rate (AIR) based partial marginalization (PM). The proposed AIR based PM (AIR-PM) detector has superior performance compared to previously proposed PM designs and other soft-output detectors such as K-best, while at the same time yielding lower computational comp

High-precision analyses of the isotopic composition of methane in ambient air can potentially be used to discriminate between different source categories. Due to the complexity of isotope ratio measurements, such analyses have generally been performed in the laboratory on air samples collected in the field. This poses a limitation on the temporal resolution at which the isotopic composition can be

In the atmosphere nighttime removal of volatile organic compounds is initiated to a large extent by reaction with the nitrate radical (NO3) forming organic nitrates which partition between gas and particulate phase. Here we show based on particle phase measurements performed at a suburban site in the Netherlands that organic nitrates contribute substantially to particulate nitrate and organic mass

Cloud computing technology provides the means to share physical resources among multiple users and data center tenants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such is virtual networking services, so called services chains, which consist of several interconnected virtual network functi

This paper combines the Metropolis-Hastings Improved Particle Smoother (MHIPS) with marginalized models. It demonstrates the effectiveness of the combination by looking at two examples; a degenerate model of a double integrator and a fifth order mixed linear/nonlinear Gaussian (MLNLG) model. For the MLNLG model two different methods are compared with the non-marginalized case; the first marginaliz

Sufficient conditions for stability of feedback interconnections of negative imaginary systems are derived via an integral quadratic constraint (IQC) approach. These extend existing results in the literature by exploiting the flexibility present at the static and infinite frequencies to reduce conservatism. Negative imaginary transfer functions with poles on the imaginary axis are accommodated usi

We focus on the problem of semantic segmentation based on RGB-D data, with emphasis on analyzing cluttered indoor scenes containing many visual categories and instances. Our approach is based on a parametric figureground intensity and depth-constrained proposal process that generates spatial layout hypotheses at multiple locations and scales in the image followed by a sequential inference algorith

Stereo rendering for 3D displays and for virtual reality headsets provide several visual cues, including convergence angle and high- light disparity. The human visual system interprets these cues to estimate surface properties of the displayed environment. Naïve stereo rendering effectively doubles the computational burden of image synthesis, and thus it is desirable to reuse as many computa- tion