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Background: Cystatin C may add explanatory power for associations with mortality in combination with other filtration markers, possibly indicating pathways other than glomerular filtration rate (GFR). However, this has not been firmly established since interpretation of associations independent of measured GFR (mGFR) is limited by potential multicollinearity between markers of GFR. The primary aim

Climate during the Last Interglacial period (LIG, Marine Isotope Stage 5e) was on average warmer than the present, with a higher global sea level but also more unstable conditions. Today, the Baltic Sea interacts strongly with conditions in the North Atlantic region, and this interaction was likely even stronger during the LIG. We here present a reconstruction of seawater conditions during the LIG

The geomagnetic dipole moment (GDM) modulates the production rates of cosmogenic radionuclides via the shielding of galactic cosmic rays. Therefore, it is possible to use this linkage to reconstruct past changes in the GDM based on cosmogenic radionuclide records from natural archives such as ice cores. Here we present a GDM reconstruction based on 10Be and 36Cl data from two Greenland ice cores f

Generalized alternating projections is an algorithm that alternates relaxed projections onto a finite number of sets to find a point in their intersection. We consider the special case of two linear subspaces, for which the algorithm reduces to matrix multiplications. For convergent powers of the matrix, the asymptotic rate is linear and decided by the magnitude of the subdominant eigenvalue. In t

Employing lightweight, tool-based code review of code changes (aka modern code review) has become the norm for a wide variety of open-source and industrial systems. In this paper, we make an exploratory investigation of modern code review at Google. Google introduced code review early on and evolved it over the years; our study sheds light on why Google introduced this practice and analyzes its cu

The East Asian winter monsoon (EAWM) significantly impacts living conditions in a large part of Asia, and therefore, it is important to understand its major driving mechanisms. Winter sea surface temperature (SSTW) and circulation in the southern Okinawa Trough are today both primarily controlled by the EAWM. Here we present a new SSTW reconstruction for the last millennium based on a diatom recor

Characterizing aerosol chemical composition in response to meteorological changes and atmospheric chemistry is important to gain insights into new particle formation mechanisms. A BAECC (Biogenic Aerosols - Effects on Clouds and Climate) campaign was conducted during the spring 2014 at the SMEAR II station (Station for Measuring Forest Ecosystem-Aerosol Relations) in Finland. The particles were ch

Sensitivity tests were conducted using a state-of-the-art aerosol–cloud to investigate the key microphysical and dynamical mechanisms by which solid aerosols affect glaciated clouds. The tests involved simulations of two contrasting cases of deep convection—a tropical maritime case and a midlatitude continental case, in which solid aerosol concentrations were increased from their pre-industrial (1

We present a study on the stratospheric aerosol load during 2006-2015, discuss the influence from volcanism and other sources, and reconstruct an aerosol optical depth (AOD) data set in a resolution of 1° latitudinally and 8 days timewise. The purpose is to include the "entire" stratosphere, from the tropopause to the almost particle-free altitudes of the midstratosphere. A dynamic tropopause of 1

Time-dependent ensemble averages, i.e., trajectory-based averages of some observable, are of importance in many fields of science. A crucial objective when interpreting such data is to fit these averages (for instance, squared displacements) with a function and extract parameters (such as diffusion constants). A commonly overlooked challenge in such function fitting procedures is that fluctuations

Numerical weather prediction models are increasing in resolution and becoming capable of explicitly representing individual convective storms, but we do not yet know if it is the improved resolution that is leading to better forecasts.

The Younger Dryas (YD) cold reversal interrupts the warming climate of the deglaciation with global climatic impacts. The sudden cooling is typically linked to an abrupt slowdown of the Atlantic Meridional Overturning Circulation (AMOC) in response to meltwater discharges from ice sheets. However, inconsistencies regarding the YD-response of European summer temperatures have cast doubt whether the

The Holocene Series/Epoch is the most recent series/epoch in the geological timescale, spanning the interval from 11,700 yr to the present day. Together with the subadjacent Pleistocene, it comprises the Quaternary System/Period. The Holocene record contains diverse geomorphological, biological, climatological and archaeological evidence, within sequences that are often continuous and extremely w

The second phase of the Fifth International Ice Nucleation Workshop (FIN-02) involved the gathering of a large number of researchers at the Karlsruhe Institute of Technology's Aerosol Interactions and Dynamics of the Atmosphere (AIDA) facility to promote characterization and understanding of ice nucleation measurements made by a variety of methods used worldwide. Compared to the previous workshop

During the transition from the last glacial into the Holocene interglacial, the atmospheric circulation in the North Atlantic area changed from a glacial mode, influenced by the presence of large ice sheets, into a system more similar to that of the present day. This change had implications for wind, temperature and precipitation patterns that can be traced in geological archives. Here, we focus o

This article summarizes the processes that are responsible for cosmogenic radionuclide variations in ice cores and the results that can be inferred from these records. The article starts with the production in the atmosphere caused by the influx of galactic cosmic ray particles and its modulation by the solar and geomagnetic fields. Subsequently, the geochemical behavior of cosmogenic radionuclide

Timescale uncertainties between paleoclimate reconstructions often inhibit studying the exact timing, spatial expression and driving mechanisms of climate variations. Detecting and aligning the globally common cosmogenic radionuclide production signal via a curve fitting method provides a tool for the quasi-continuous synchronization of paleoclimate archives. In this study, we apply this approach

The volcanic fingerprint on the winter North Atlantic atmospheric circulation and climate is analyzed in six ensemble runs of ECHAM5/MPI-OM covering 800–2000 CE, both for equatorial and Northern Hemisphere (NH) eruptions. Large volcanic eruptions influence climate on both annual and decadal time scales due to dynamic interactions of different climate components in the Earth's system. It is well kn

Spatial correlation across an antenna array is known to be detrimental to the terminal signal-to- interference-plus-noise-ratio (SINR) and system spectral efficiency. For a downlink multiuser multiple-input multiple-output system (MU-MIMO), we show that the widely used, yet overly simplified, correlation models which generate fixed correlation patterns for all terminals tend to underestimate the s