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Objective: To investigate how genetics influence the risk of smoking-related systemic lupus erythematosus (SLE) manifestations. Methods: Patients with SLE (ndiscovery cohort=776, nreplication cohort=836) were genotyped using the 200K Immunochip single nucleotide polymorphisms (SNP) Array (Illumina) and a custom array. Sixty SNPs with SLE association (p<5.0×10-8) were analysed. Signal transducer an

Industrial cyber-physical system products interleave hardware, software, and communication components. System complexity is increasing simultaneously with increased demands on quality and shortened time-to-market. To effectively support the development of such systems, we present languages and tools for comprehensive integrated model-based development that cover major phases such as requirement an

Objective: To identify factors affecting the outcome after open surgical (OSR) and endovascular (ER) repair of popliteal artery aneurysm (PA) in comparable cohorts. Methods: A matched comparison in a national, population based cohort of 592 legs treated for PA (2008 – 2012), with long term follow up. Registry data from 899 PA patients treated in 2014 – 2018 were analysed for time trends. The 77 le

Generalized low-density parity-check (GLDPC) codes are a class of LDPC codes in which the standard single parity check (SPC) constraints are replaced by constraints defined by a linear block code. These stronger constraints typically result in improved error floor performance, due to better minimum distance and trapping set properties, at a cost of some increased decoding complexity. In this paper

Context: Continuous experimentation and A/B testing is an established industry practice that has been researched for more than 10 years. Our aim is to synthesize the conducted research. Objective: We wanted to find the core constituents of a framework for continuous experimentation and the solutions that are applied within the field. Finally, we were interested in the challenges and benefits repor

Context. Continuous experimentation is used by many companies to improve their products with users data. In this study, the efficacy of continuous experimentation as used in two different types of business models (product-led or sales-led). Method. Two case companies with a product-led business model and three companies with sales-led business model were compared against each other. 14 interviewee

Testing of autonomous systems is extremely important as many of them are both safety-critical and security-critical. The architecture and mechanism of such systems are fundamentally different from traditional control software, which appears to operate in more structured environments and are explicitly instructed according to the system design and implementation. To gain a better understanding of a

Correlation between different links is an essential characteristic for many of the forthcoming radio communication systems that utilize the multiple-input-multiple-output (MIMO) technology. This paper investigates the physical phenomena that cause the inter-link correlation by introducing a measure to quantify how large amount of energy propagates via similar propagation mechanisms in different li

In this paper we consider spatial coupling in turbo equalization and demonstrate that the code design trade-off between the performance in waterfall and error floor regions can be avoided. We introduce three coupling schemes and compare their performances, where the first method introduces coupling between the encoder and the channel, while the second uses a spatially coupled (SC) code. In the thi

A Large Intelligent Surface (LIS) is a recently proposed concept, especially suitable for high speed indoor communications and industrial internet of things (IoT) applications. Basing the LIS on smaller panels has clear advantages in terms of flexibility and mass production of its elements. In this paper we consider a panel-based LIS and we study the interplay of the panel size, the number of base

Context: The European Association of Urology (EAU) has released an updated version of the guidelines on non–muscle-invasive bladder cancer (NMIBC). Objective: To present the 2021 EAU guidelines on NMIBC. Evidence acquisition: A broad and comprehensive scoping exercise covering all areas of the NMIBC guidelines since the 2020 version was performed. Databases covered by the search included Medline,

Stereo 3D video from surgical procedures can be highly valuable for medical education and improve clinical communication. But access to the operating room and the surgical field is restricted. It is a sterile environment, and the physical space is crowded with surgical staff and technical equipment. In this setting, unobscured capture and realistic reproduction of the surgical procedures are diffi

Background: Knee pain is studied mostly in older age groups, although in young adults it may be an indicator of future impaired musculoskeletal health. Therefore, the aim of this study was to examine the longitudinal association between knee pain and thigh muscle strength in young adult women and to explore the associations between muscle strength, body composition, physical activity and knee pain

Objective: To investigate if the extent of absent end-diastolic flow (AEDF) on umbilical artery (UA) Doppler velocimetry predicts pregnancy outcome. Methods: This was a retrospective observational study based on data from 25 000 Doppler examinations of UA flow performed between 1998 and 2017 at the Blood Flow Laboratory, Level III Perinatal Center, Lund, Sweden. All pregnancies with AEDF in the UA

We use the received bit information rate (RBIR) to analyze the performance of multi-layer transmission when combined with hybrid automatic repeat request (HARQ). The different layers are obtained from ordinary Gray-coded M-QAM and used for transmitting log2(M) codewords in parallel, exploiting that the different bits in Gray-coded M-QAM have very different reliability. The performance is analyzed

We present a localization algorithm for low-power long-range Internet-of-things (IoT) networks, which exploits angle of arrival (AoA) and range information from non-coherent received signal strength (RSS) measurements. In this work, each anchor node is equipped with array antennas of known geometry and radiation patterns. The position of the target node and the path-loss exponent to each anchor ar

Peanut (Arachis hypogaea L.) is an important oilseed crop worldwide, and peanut height has been shown to be closely related to yield, therefore a better understanding of the genetic base of plant height-related traits may allow us to have better control of crop yield. Plant height-related traits are quantitative traits that are genetically controlled by many genes, and distinct quantitive trait lo