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Structured triacylglycerols (STAG) with desired properties can be synthesized by transesterification using immobilized lipases. Herein, the effect of immobilization conditions and support material on the immobilization yield, specific activity and regioselectivity of lipases from Rhizomucor miehei (RML) and Rhizopus oryzae (ROL) in the production of STAG, are evaluated. Four different support mate
Around one-fourth of the global population lacks access to clean fuels and technologies for cooking, most of them living in low- and middle-income countries. Reliance on rudimentary and inefficient biomass cookstoves results in high pollutant concentrations that adversely affect the health of those exposed to indoor air pollution, the environment, and the climate. In this study, we systematically
Pixel sensors in 3D technology equip the outer ends of the staves of the Insertable B Layer (IBL), the innermost layer of the ATLAS Pixel Detector, which was installed before the start of LHC Run 2 in 2015. 3D pixel sensors are expected to exhibit more tolerance to radiation damage and are the technology of choice for the innermost layer in the ATLAS tracker upgrade for the HL-LHC programme. While
We are on a hunt for the invisible in this second episode of the third season of The Meridian. Ruth Pöttgen is a senior lecturer at the Department of Physics where she is studying fundamental particles. She is especially interested in finding that mysterious and elusive Dark Matter particle.In this third season we are also including some Cosmic Curiosities. These are some ideas, events or trivia
Proteins and peptides are vital biomolecules, and deuterated amino acids are increasingly applied in areas such as drug discovery, metabolic tracing, and neutron scattering studies. In this study, we performed deuteration on all 20 proteinogenic amino acids, including their side chains, and established efficient methods for 13 amino acids. Using a Pt/C-catalyzed hydrogen–deuterium exchange reactio
The retinoblastoma gene (RB1), which is located on chromosome 13q14.2, is mutated in retinoblastoma (RB), the most common malignant intraocular tumor in children. About 8000 new cases of retinoblastoma are diagnosed globally each year, accounting for approximately 1 in 17,000 live births. RB is prototypically considered hereditary by nature as thirty to forty percent of cases have autosomal domina
The Cherenkov Telescope Array (CTA) is the future observatory for ground-based imaging atmospheric Cherenkov telescopes. Each telescope will provide a snapshot of gamma-ray induced particle showers by capturing the induced Cherenkov emission at ground level. The simulation of such events provides camera images that can be used as training data for convolutional neural networks (CNNs) to differenti
Dopaminergic neurons in the ventral midbrain are critical for regulating movement, cognition, and emotion. Ventral midbrain organoids can be used to model both development and diseases of the dopaminergic system, especially Parkinson’s disease. Here, we summarize recent advances and remaining challenges in developing such three-dimensional organoids from human pluripotent stem cells. We outline ho
The establishment of innovation ecosystems has become an increasingly prevalent strategy for fostering territorial, economic and social development. However, the existing literature provides limited insights into the strategic conditions that enable the emergence of such ecosystems. This paper addresses this gap by identifying the critical elements and mechanisms underpinning their creation. Speci
A strategy for the formation of thin reconstituted cellulose films (pure or modified)) with embedded receptors or embedded ion-selective components is reported. Cellulose nanofibril ribbons from sisal of typically 3-5 nm diameter and 250 nm length are reconstituted into thin films of typically 1.5-2.0 μm thickness (or into thicker free-standing films). Cellulose and cellulose nanocomposite films a
Using a model disordered mesoporous solid with a spatial arrangement of pore sizes analogous to a macroscopic 'ink-bottle', it has been shown that the hysteresis observed in NMR cryoporometry can be deconvoluted into separate single pore and pore-blocking contributions. The suggestion of pore-blocking effects has been confirmed using PFG NMR. Hence, percolation theory has been used, for the first
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of caffeine compared to aminophylline or theophylline in preterm infants at risk of apnea, with apnea, or in the peri-extubation phase.
Universities are increasingly being seen as a positive vehicle for territorial development and regional transformation, with an important role in enhancing Social, Economic and Sustainable Development of territories. The world’s sustainability challenges are listed in the United Nation’s Agenda 2030, that includes Higher Education Institutions (HEIs) as actors that can work in partnership with oth
This study addresses the critical need to report original and current findings on the global food system's ability to meet the growing natural resource demands of an estimated 9?billion global population. The objective is to provide guidance for researchers in developing strategies to reduce climate change risks in the food and beverage supply. To achieve this, we propose integrating innovative in
Production and use of chlorophenols (CPs) are being phased out around the globe, but with considerable lag in some highlypopulated countries. The process could be incentivized by leading countries sharing their experiences on problems thatoccurred, including the built environment. We previously reported that Swedish industry and authorities promoted CPs,including pentachlorophenol (PCP), as wood p
In this fascinating biography of the Indian revolutionary M. P. T. Acharya (1887–1954), Ole Birk Laursen uncovers the remarkable transnational networks, movements and activities of India’s most important anticolonial anarchist in the twentieth century.Driven by the urge for complete freedom from colonialism, authoritarianism, fascism and militarism, which are rooted in the idea and politics of the
