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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Här hittar du som är student eller medarbetare hos oss information om valbara kurser, kalendarium för hela terminen. JanuaryWeek 3: 15-21 January15.1    Official start of spring semester15.1     MFAAR meeting 10.00-11.0015.1     Meeting with the exchange students 11.00-11.3015.1    ALL STUDENTS 12.00-13.00 Student forum with lunch WELCOME TO NEW SEMESTER 19.1    Application portal BFA and MFA prog

https://www.khm.lu.se/varterminen-2024 - 2026-05-09

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus Lundgren, MD; Denise Müller, BSc; Mariusz Oltarzewski, PhD; Anne Rochtus, MD; M

https://www.gppad.lu.se/sites/gppad.lu.se/files/2024-01/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-05-11

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus L

https://www.gppad.lu.se/sites/gppad.lu.se/files/2023-10/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-05-11

Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r

https://www.energy.lth.se/research/energy-storage-conversion - 2026-05-09

ORNIS SCANDINAVICA 9: 31-29. Copenhagen 1978. The effect of observer variability on bird census results obtained by a territory mapping technique Anders Enemar Zoological Institute, University of Gothenburg, Sweden Bengt Sjostrand Institute of Marine Research, Lysekil, Sweden Soren Svensson Department of Animal Ecology, University of Lund, Sweden Enemar, A., Sjostrand, B. and Svensson, S. 1978. Th

https://www.luvre.lu.se/sites/luvre.lu.se/files/luvre-035enemarmflinventerarvariation.pdf - 2026-05-11

The digital games industry is one of the fastest growing branches in the creative sector in Sweden: In the last three years the proportion of employees has increased with about 20 percent. Specific for this branch is that digital games companies compete in a highly globalized and digitalized market dominated by a few large corporations. It creates the backdrop for specific working conditions. PrevThe digital games industry is one of the fastest growing branches in the creative sector in Sweden: In the last three years the proportion of employees has increased with about 20 percent. Specific for this branch is that digital games companies compete in a highly globalized and digitalized market dominated by a few large corporations. It creates the backdrop for specific working conditions. Prev

We present a theoretical investigation of a model clay dispersion in 1-1 salt solutions by varying the particle volume fraction and ionic strength as well as the charge distribution on the clay platelets. The platelets are modeled as discs with charged sites distributed on a hexagonal lattice. The edge sites can be positively charged while the remaining sites are negative giving rise to a strong c

Background: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. Methodology/Principal Findings: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as kd) of naturally acquired antibodies to the Plasmodium falciparum antigens MSP2 and AMA1. Antibodies in serum samp