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Protease Inhibitors or NNRTIs as First-Line HIV-1 Treatment in West Africa (PIONA) : A Randomized Controlled Trial

BACKGROUND: Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are recommended as part of first-line treatment for HIV-1 in Africa. However, NNRTI-based regimens are more prone to resistance development than protease inhibitors (PIs) in a context in which drug interruptions are frequent. The aim of this study was to compare the efficacy and tolerability of NNRTIs with PIs in HIV-1-infected pa

Sex differences in risk factor control of treated hypertensives: a national primary healthcare-based study in Sweden.

BACKGROUND: To evaluate potential sex differences, this study aimed to investigate blood pressure and lipid control and other risk factors for cardiovascular disease in treated hypertensive (tHT) patients from primary healthcare. DESIGN AND METHODS: This cross-sectional survey of tHT patients was carried out between 2002 and 2005 by 264 primary care physicians from Sweden who consecutively recruit

Comparison of busulphan, hydroxyurea and allogeneic bone marrow transplantation (BMT) in chronic myeloid leukaemia: BMT prolongs survival

Introduction: Whether busulphan -treated patients develop blastic transformation earlier than hydroxyurea treated has been a controversial issue. In a randomised prospective study, we examined the busulphan versus hydroxyurea influence on time to blast crisis and on survival. When we opened our study in 1984, the clinical benefit of allogeneic bone marrow transplantation (BMT) was not well known;

90Yttrium-Ibritumomab-Tiuxetan as First-Line Treatment for Follicular Lymphoma: 30 Months of Follow-Up Data From an International Multicenter Phase II Clinical Trial.

PURPOSEWe report on a multicenter phase II trial of (90)yttrium-ibritumomab-tiuxetan ((90)YIT) as first-line stand-alone therapy for patients with follicular lymphoma (FL). PATIENTS AND METHODSFifty-nine patients with CD20(+) FL grade 1 to 3a in stages II, III, or IV, age 50 years old or older requiring therapy were enrolled. They received (90)YIT according to standard procedure. If complete respo

Cystatin C : a new marker of biocompatibility or a good marker for the redistribution of LMW proteins during hemodialysis?

The mechanism(s) behind the larger relative increase of Plasma beta 2 microglobulin (P-beta 2m) than that of Plasma albumin (P-alb) during Cuprophan hemodialysis is disputed. To elucidate this phenomenon P-alb, P-beta 2m (MW 11,800) and Plasma cystatin (P-cC; MW 13,000) an inhibitor of cystein proteinases, were determined before and after a Cuprophan or polysulphone hemodialysis (4-7 hr, QB 200 ml

Who should record surgical complications? Results from a third-party assessment of complications after radical cystectomy

Objective: In Sweden complications after radical cystectomy have been reported to the nationwide population-based Swedish Cystectomy Registry since 2011. Here, validation of the reporting was assessed in two healthcare regions. Materials and methods: Complications were ascertained from patient records by a third party not involved in the care delivered to 429 randomly selected patients from 949 wh

Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centres completed a structured questionnaire on cause of death and comorbidities. Kaplan-Meier and Cox pro

Higher Prescribed Opioid Use Among Adults With Crohn's Disease Than General Population : A Nationwide Cohort Study in Sweden 2006–2021

Background and Aims: Population-based data on prescribed opioid use among adults with Crohn's disease (CD) remain limited. Methods: This nationwide register-based study included individuals ≥ 18 years with incident (2008–2019) or prevalent (2008–2021) CD and up to 10 individually matched reference individuals without inflammatory bowel disease. We categorised opioid dispensations as weak (e.g., tr

Efficacy of the antibacterial envelope to prevent cardiac implantable electronic device infection in a high-risk population

AimsInfection is a serious complication of cardiac implantable electronic device (CIED) therapy. An antibiotic-eluting absorbable envelope has been developed to reduce the infection rate, but studies investigating the efficacy and a reasonable number needed to treat in high-risk populations for infections are limited.Methods and resultsOne hundred and forty-four patients undergoing CIED implantati

Basal Metabolic Requirements, Biomarkers of Cardiometabolic Health, and Anthropometric Measures of Obesity in Women and Men With Restricted Growth Conditions

Population-specific thresholds have not been defined for the levels of adiposity and systemic biomarkers that predict chronic health risks in people with restricted growth conditions. Here, anthropometric measures of adiposity, basal metabolic requirements, and fasted blood samples were obtained from adults with restricted growth (age 41 ± 14 years, height 1.30 ± 0.10 m, body mass 60.5 ± 18.3 kg,

Endoscopic and Surgical Management of Non-Metastatic Ampullary Neuroendocrine Neoplasia : A Multi-Institutional Pancreas2000/EPC Study

Introduction: Ampullary neuroendocrine neoplasia (NEN) is rare and evidence regarding their management is scarce. This study aimed to describe clinicopathological features, management, and prognosis of ampullary NEN according to their endoscopic or surgical management. Methods: From a multi-institutional international database, patients treated with either endoscopic papillectomy (EP), transduoden

Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) impacts many veterans and active duty soldiers, but diagnosis can be problematic due to biases in self-disclosure of symptoms, stigma within military populations, and limitations identifying those at risk. Prior studies suggest that PTSD may be a systemic illness, affecting not just the brain, but the entire body. Therefore, disease signals likely span multipl

Cfewp25

25.p65 1Discussion of some Legal Issues Raised by the Introduction of the Euro Discussion of Some Legal Issues Raised by the Introduction of the Euro Cécile Brokelind cecile.brokelind@busilaw.lu.se 2 CFE Working paper series no. 25 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06 Sweden Email: cfe@cfe.lu.se CFE Working paper

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp25.pdf - 2026-05-20

121 MP193 Webb-Robertson JDiabetes 2020 (2)

Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers OR I G I N A L AR T I C L E Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers Bobbie-Jo M. Webb-Robertson1,2 | Lisa M. Bramer3 | Bryan A. Stanfill3 | Sarah M. Reehl3 | Ernesto S. Nakayasu1 | Thomas O. Met

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-06/121_MP193_Webb-Robertson_JDiabetes_2020%20(2).pdf - 2026-05-20

Intro Metodval Feb 2022 - REVISED

Intro metodval feb 2022 - REVISED More details about the courses: Method courses Spring term 2022 Information meeting January 31 https://tinyurl.com/MethodElectives https://tinyurl.com/MethodElectives Method courses Spring term 2022 Yagmur Yilmaz Programme Coordinator Chris Swader Director of Studies Kadri Kuusk Methods Director • Introduction • The application process • Presentation of courses •

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2022-01/Intro%20metodval%20feb%202022%20-%20REVISED.pdf - 2026-05-20

Corvellec 2016 wastepreventionsweden rapport

Waste prevention in Sweden 2008-2015 - An analysis of key waste prevention initiatives HERVÉ CORVELLEC DEPARTMENT OF SERVICE MANAGEMENT AND SERVICE STUDIES Waste prevention in Sweden 2008-2015 - An analysis of key waste prevention initiatives HERVÉ CORVELLEC © Hervé Corvellec April 2016 The Department of Service Management and Service Studies, Lund University herve.corvellec@ism.lu.se LUND UNIVERS

https://www.ses.lu.se/sites/ses.lu.se/files/corvellec_2016_wastepreventionsweden_rapport.pdf - 2026-05-20

A day at work: Nobel Prize joy behind the scenes

3 October – the Tuesday of the so-called Nobel Week – will go down in history as the day when LTH and Lund University received their very first Nobel Prize. At the same time, to all of us, it was a working day among many. Communication Officer Evelina Lindén, who divides her working hours between Fysicum and LTH’s secretariat, writes about what it was like to suddenly have her workplace invaded by

https://www.lthin.lth.se/en/article/2023/day-work-nobel-prize-joy-behind-scenes - 2026-05-19