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Relation between the rate of tumour cell proliferation and latency time in radiation associated breast cancer.

Background: Patients with possible radiation induced cancer could be used to study if the rate of tumour cell proliferation is related to latency time. Such a finding could help researcher to find time periods when other initiating risk factors operate. Methods: Seventeen women with breast cancer, with a prior history of radiation treatment towards the parts or the whole breast, exclusive of the p

Studies on the interaction between vitamin K-dependent protein S and complement regulator C4b-binding protein: localization of binding sites and identification of a possible function of the complex.

Complement is a cascade-like system that is part of the innate immune defence. It is an explosive system, potentially harmful also for the host cells, and needs to be strictly regulated. An important down-regulator of complement is C4b-binding protein (C4BP). C4BP contains two different types of subunits, seven identical a-chains and one unique P-chain. The alpha-chains bind to C4b, C4BP's target

Substitution reactions of [Pt(dien)Cl](+), [Pt(dien)(GSMe)](2+), cis-[PtCl2(NH3)(2)] and cis-[Pt(NH3)(2)(GSMe)(2)](2+) (GSMe = S-methylglutathione) with some sulfur-bonding chemoprotective agents

Sulfur-containing compounds are used as rescue agents to protect normal tissue from the toxic side effects of cis-[PtCl2(NH3)(2)] (cisplatin) without affecting its anti-tumour activity. Reactions of the model complexes [Pt(dien)Cl](+) (1) and [Pt(dien)(GSMe)](2+) (2) (GSMe = S-methylglutathione) with the rescue agents glutathione (GSH), thiourea, thiosulfate, and diethyldithiocarbamate (DDTC) have

Underhållsstödet - familjepolitikens albatross : 1997 års underhållsstödsreform och dess betydelse för de bidragsskyldiga föräldrarna

A new law regarding child-maintenance was issued in Sweden in 1997. The main purpose of the reform was to make the system more cost-efficient, in order to minimise government expenditure. This was done by advocating a more individualised economic responsibility, as well as new rules for how to calculate maintenance levels. Almost five years later it is clear that the economic goals have not been

Surgical Care in Liberia and Implications for Capacity Building

BACKGROUND: Situational needs of health care facilities inform the optimal allocation of resources and quality improvement efforts. This study examines surgical care delivery metrics at a tertiary care institution in Liberia. METHODS: We retrospectively reviewed operative and ward logbooks from January 1 to December 31, 2012. Data parameters included patients' age, diagnosis, procedure, mortality,

Structure and spectrum of the hydrated electron. A combined quantum chemical statistical mechanical simulation

In the current work, in order to model a free electron solvated in water, we have implemented a method to represent the molecular charge distribution as a set of Slater-type functions within the framework of a QM/MM method called QMSTAT. Also, it has been introduced in this method a new approach to calculate the intermolecular induction energy in the presence of very strong electric fields. Unlike

Satisfaction with care in late stage Parkinson's disease

In late stage Parkinson's disease (PD) (i.e., Hoehn and Yahr (HY) stages IV-V), both motor and nonmotor symptoms (NMS) are pronounced, and the patients become increasingly dependent on help in their daily life. Consequently, there is an increasing demand on health-care and social care resources for these patients and support for their informal caregivers. The aim of this study was to assess satisf

Diskonteringsräntan vid nedskrivning av goodwill

Titel: Diskonteringsräntan vid nedskrivning av goodwill - En jämförelsestudie av marknadsmässiga bedömningar Seminariedatum: 2014-05-23 Ämne/kurs: FEKN90, Företagsekonomi: Examensarbete i Corporate Finance på magisternivå. 30hp. Författare: Victor Håkansson och Anton Persson Handledare: Erling Green Nyckelord: Goodwill, nedskrivningsprövning, diskonteringsränta, marknadsmässiga bedömningar ocTitle: The discount rate used in the impairment testing of goodwill – A comparison of market-based assessments Seminar date: 2014-05-23 Course: FEKN90, Business Administration: Master Thesis in Corporate Finance, 30 HP Authors: Victor Håkansson and Anton Persson Advisor: Erling Green Key words: Goodwill, impairment testing, discount rate, market-based assessments and IAS 36. Purpose: The pur

Straffvärdet vid underlåtenhetsbrott – Underlåtenhet som en förmildrande omständighet?

Syftet med uppsatsen är att genom en rättsdogmatisk metod och ett kritiskt perspektiv granska hur underlåtenhet påverkar bedömningen av straffvärdet i en domstols straffmätning och undersöka om underlåtenhet verkligen ska ses som en förmildrande omständighet. Uppsatsen behandlar själva utformningen av principerna kring underlåtenhetsbrott enligt Jareborgs garantlära i svensk rätt idag och en utredThe purpose of this essay is to use a legal dogmatic method, and with a critical perspective, analyse how the fact that a crime is one of omission, thus caused by a failure to act, affects the Court's judgement on a suitable sentence. Is the fact that a crime is an omission automatically a mitigating factor that leads to a lesser sentence? This essay treats the general legal principles and the

Effects of biomanipulation on benthic invertebrates, condition and foraging behavior of benthic fish

Genom att minska mängden planktivor och bottenlevande fisk (reduktionsfiske eller biomanipulation) kan vattenkvalitén och den ekologiska statusen i övergödda sjöar förbättras. Om metoden utförs effektivt ger den positiva effekter på siktdjup, algmängd samt biodiversitet vilket ökar möjligheterna för rekreation och dricksvatten. En viktig upptäckt vid reduktionsfisken är att bottenlevande fisk har Biomanipulation, i.e. to reduced planktivorous- and benthivorous fish in order to receive changes in the trophic structure has been a successful method to improve water quality and the ecological status in eutrophic lakes. The initial idea was to increase the abundance of large zooplankton and thus to cause a trophic cascade with reduced algal biomass. Many studies failed to observe an increase of

Heat processing and storage of a berry-based beverage and its influence on polyphenolic compounds – a preparatory analysis of a study product for a clinical trial

Research suggests that polyphenols, such as anthocyanins, that are found in considerable amounts in many types of berries, contributes with a positive effect on human cognition. However, clinical trials are warranted to support these findings. Preparation for such a trial includes developing a berry-rich study product and a corresponding reference beverage. Phenolic compounds are highly unstable a

Food waste prevention in quick service restaurants: A comparative case study on the quantity, source, costs and cause

This research aims to fill the knowledge gap with regards to food waste prevention with a specific focus on quick service restaurants (QSRs) – also known as fast food restaurants. Restaurants are in a prime position to reduce food waste produced in the consumptive stages of the food supply chain, and more focus should be placed on how restaurants can help achieve food waste reduction targets. The

Värdering av tomtmark med hus på ofri grund vid klyvning

Värdering av obebyggd tomtmark för småhus kan ibland vara svårt då det saknas ett bra ortsprismaterial. Ännu svårare är att värdera tomtmark för småhus som är bebyggda med byggnader på ofri grund. Tomtmark med byggnader på ofri grund upplåtna med nyttjanderätter anses ha ett lägre värde än tomtmark som är obebyggd eller tomtmark som är bebyggd av fastighetens ägare. Det beror på att nyttjanderätteThe objective of this work is to examine the impact on value that a house on leasehold has on the underlying land in a partition ordinance. In order to build a foundation and create an understanding about houses on leasehold, partitiontools and different methods of valuation I undertook literature studies. The literature consisted of, among other things, preparatory work for FBL and the Court of A

Objektivitetsprincipen - en rättspsykologisk omöjlighet? Om möjligheten att upprätthålla rättssäkerheten vid förundersökning av grova brott.

Thomas Quick erkände under 1990-talet ett 30-tal mord som han påstod att han begått i Sverige, Norge, Danmark, och Finland under åren 1964-1993. Han dömdes för åtta av dem. 18 år senare, i december 2008, tar han tillbaka alla sina erkännanden av mord och begär resning för samtliga fällande domar. Detta har hittills resulterat i tre frikännande domar samt två positiva resningsbeslut. Pelle Svensson1990 Thomas Quick confessed to around 30 murders that he claimed to have committed in Sweden, Norway, Denmark and Finland around the years 1964-1993. He was convicted for eight of them. 18 years later he takes back his confessions of murder and applies for remedy for all his convictions. This has so far resulted in three acquittals and five granted trials of remedy. Pelle Svensson, lawyer and auth

Component depreciation in real estates will the burdens in practice only be leveled up by benefits in theory

Seminar date: 2012-05-30 Course: BUSN69 Business Administration: Degree Project – Accounting and Auditing Authors: Mathias Andersson and Fredrik Aprili Advisor: Kristina Artsberg Five key words: Depreciation, component depreciation, K3, real estate and standard-setting. Purpose: Our purpose with this thesis is to reveal the effects that component depreciation can have on Swedish non-listed rea

The micrometeorite flux in the Albian–Aptian age (ca. 103–117 Ma): A search for Tycho ejecta in pelagic sediments using chrome spinels

Numerical models of meteorite delivery from impacts on the Moon have demonstrated that the impact event forming the lunar crater Tycho (~85 km diameter; ca. 109 Ma age) would have delivered considerable amounts of ejected material to Earth. The ejecta, containing lunar Ti- and V-rich chrome spinels, would have been distributed globally and admixed with seafloor sediments over a few meters of a typ

A global map of groundwater-dependent vegetation in the Mediterranean biome

Groundwater-dependent vegetation (GDV) plays a vital role in maintaining biodiversity and ecosystem services in the Mediterranean biome but is increasingly threatened by climate and land use change. Large-scale GDV mapping in arid regions is critical for effective conservation and water resource management but remains challenging due to limited ground-truth data and the lack of high-resolution rem

Two warm Earth-sized exoplanets and an Earth-sized candidate in the M5V-M6V binary system TOI-2267

We report the discovery of two warm exoplanets orbiting the cool binary system TOI-2267, composed of the M5 (TOI-2267A) and M6 (TOI-2267B) stars, whose angular separation is 0.384 arcsec, corresponding to a projected distance of only about 8 au at 22 pc from the Solar System. To confirm the planetary nature of these objects, we combined photometry from the Transiting Exoplanet Survey Satellite (TE

Immediate skin-to-skin contact at very preterm birth and effect on infant socio-emotional stress response and mother–infant cortisol co-regulation : secondary outcomes from the randomised clinical Immediate Parent-Infant Skin-To-Skin Study (IPISTOSS)

Objective To explore the effects of immediate parent–infant skin-to-skin contact (iSSC) at very preterm birth on maternal–infant behavioural responses and hypothalamic–pituitary–adrenal (HPA) axis reactivity to age-appropriate socio-emotional stress at 4months corrected age. Design Two secondary outcomes from a multicentre randomised controlled trial with two non-blinded parallel groups. Setting T