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The impact of dyslipidaemia on incidence of coronary heart disease in Finns and Swedes with different categories of glucose tolerance

Background: The association of dyslipidaemia with incidence of coronary heart disease (CHD) has not been well studied in people with different glucose categories. Methods: Data from six population-based prospective studies in Finland and Sweden, with 4818 men and 4269 women aged 25-89 years who were free of CHD and without a prior history of diabetes at baseline, were jointly analysed. Multivariat

Genetic diversity, temporal dynamics, and host specificity in blood parasites of passerines in north China.

Avian blood parasites have been preliminarily studied in East Asia, but no data are available from long-term monitoring. The aim of this study was to evaluate the prevalence, genetic diversity, and temporal dynamics of Plasmodium, Haemoproteus, and Leucocytozoon in two passerine communities (one forest and one urban) in north China from 2008 to 2013, as well as the association between infected lin

Posterior laryngitis: a study of persisting symptoms and health-related quality of life.

Posterior laryngitis is a common cause of chronic cough, hoarseness, voice fatigue and throat pain. The aim of the present study was to examine how patients with posterior laryngitis have been examined, treated and followed up, and to assess their present health-related quality of life (HRQOL). Patients treated for posterior laryngitis at consultation at the ear-, nose- and throat clinic during 20

Urak Lawoi - Sea Nomads in Andaman Sea

Lotta Granbom, a mother of three from Sweden is on holiday in Thailand. It is her first trip there together with her daughter Ebba-Lotta. After some difficulty finding accommodation at the tourist resorts, they decide instead to search for Sea Nomads in the Andaman Sea. Lotta has heard of a nomadic group of people who live on the sea around Thailand, Burma, Malaysia, Singapore, Philippines and Ind

Dosimetry and growth hormone deficiency following cranial irradiation of childhood brain tumors

Background. Dosimetry of the hypothalamus-pituitary (HP) region could allow prediction of the risk of growth hormone deficiency (GHD) following cranial irradiation. Procedure. Nineteen children (15 boys) with a median age of 6.3 years (range 1.7–16.5) at the time of irradiation of a brain tumor not involving the HP axis were followed for 1.2–6.3 years (median 3.4) from radiotherapy (RT). The dose

Cytochrome c biogenesis in Bacillus subtilis. Identification and analysis of ccdA

Popular Abstract in Swedish Cytokromer bär hem som prostetisk grupp och ingår i den energi givande andningskedjan. Cytokromer namnges beroende på strukturen av den hem-molekyl som respektive cytokrom bär. Cytokrom av a-typ innehåller hemA, cytokrom av b-typ innehåller hemB osv. Cytokrom av c-typ skiljer sig från övriga cytokrom genom att ha hemgruppen kovalent bunden till proteinet. Syntes av baktCytochromes function in electron transfer reactions, e.g. in respiratory systems, and contain haem as a prosthetic group. Cytochromes of the c-type differ from other cytochromes in that haem is covalently attached, via thioether linkages, to two cysteine residues in a conserved sequence motif in the protein, Cys-Xaa-Yaa-Cys-His. The functional location of c-type cytochromes in bacteria is on the o

A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study

We studied the impact of a family history of type 2 diabetes on physical fitness, lifestyle factors and diabetes-related metabolic factors. The Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study is a population-based study in Western Finland, which includes a random sample of 5,208 individuals aged 18 to 75 years identified through the national Finnish Population Registry. Physic

Metabolic risk factors and cervical cancer in the metabolic syndrome and cancer project (Me-Can)

Background. Little is known about the association between metabolic risk factors and cervical cancer carcinogenesis. Material and methods. During mean follow-up of 11 years of the Me-Can cohort (N = 288,834) 425 invasive cervical cancer cases were diagnosed. Hazard ratios (HRs) were estimated by the use of Cox proportional hazards regression models for quintiles and standardized z-scores (with a m

Quality of cardiopulmonary resuscitation in out-of-hospital cardiac arrest is hampered by interruptions in chest compressions-A nationwide prospective feasibility study

Aim of the study: Quality of cardiopulmonary resuscitation (CPR) is a critical determinant of outcome following out-of-hospital cardiac arrest. The aim of our study was to evaluate the quality of CPR provided by emergency medical service providers (Basic Life Support (BLS) capability) and emergency medical service providers assisted by paramedics, nurse anesthetists or physician-manned ambulances

Fewer invited talks by women in evolutionary biology symposia

Lower visibility of female scientists, compared to male scientists, is a potential reason for the under-representation of women among senior academic ranks. Visibility in the scientific community stems partly from presenting research as an invited speaker at organized meetings. We analysed the sex ratio of presenters at the European Society for Evolutionary Biology (ESEB) Congress 2011, where all

Perfusion quantification by model-free arterial spin labeling using nonlinear stochastic regularization deconvolution.

Purpose: Quantification of cerebral blood flow can be accomplished by model-free arterial spin labeling using the quantitative STAR labeling of arterial regions (QUASAR) sequence. The required deconvolution is normally based on block-circulant singular value decomposition (cSVD)/oscillation SVD (oSVD), an algorithm associated with nonphysiological residue functions and potential effects of arteria

Visibility of single spiculations in digital breast tomosynthesis

Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plan

The aetiology of pharyngotonsillitis in adolescents and adults - Fusobacterium necrophorum is commonly found.

Sore throat is common in primary healthcare. Aetiological studies have focused on the presence of a limited number of pathogens. The aim of the present study was to investigate the presence of a wide range of bacteria and viruses, including Fusobacterium necrophorum, in patients with pharyngotonsillitis and in asymptomatic controls. A prospective case control study was performed in primary healthc

New methods to identify conserved microsatellite loci and develop primer sets of high cross-species utility - as demonstrated for birds

We have developed a new approach to create microsatellite primer sets that have high utility across a wide range of species. The success of this method was demonstrated using birds. We selected 35 avian EST microsatellite loci that had a high degree of sequence homology between the zebra finch Taeniopygia guttata and the chicken Gallus gallus and designed primer sets in which the primer bind sites

The balance of serum matrix metalloproteinase-8 and its tissue inhibitor in acute coronary syndrome and its recurrence

Background: Matrix metalloproteinase-8 (MMP-8) is involved in the breakdown of the extracellular matrix increasing the vulnerability of atherosclerotic lesions. We analysed the diagnostic value of serum MMP-8 and tissue inhibitor of metalloproteinase-1 (TIMP-1) concentrations in acute coronary syndrome (ACS) and their prognostic value in ACS recurrence. Methods: The population comprised 343 patien

Strategies for the enzymatic enrichment of PUFA from fish oil

PUFA from oil extracted from Nile perch viscera were enriched by selective enzymatic esterification of the free fatty acids (FFA) or by hydrolysis of ethyl esters of the fatty acids from the oil (FA-EE). Quantitative analysis was performed using RP-HPLC coupled to an evaporative light scattering detector (RP-HPLC-ELSD). The lipase from Thermomyces lanuginosus discriminated against docosahexaenoic

The structure of allozyme variation in Silene nutans (Caryophyllaceae) in Denmark and in north-western Europe

We used allozymes to investigate the structure of genetic variation in populations of the perennial herb Silene nutans at local (Denmark), regional (Nordic area) and wide (over a 19A degrees latitudinal gradient) geographic scales in north-western Europe. New data from Denmark were combined with data from previously studied Fennoscandian and western populations. We related patterns of nuclear vari

The Comparison of Trial Data-Based and Registry Data-Based Cost-Effectiveness of Infliximab Treatment for Rheumatoid Arthritis in Sweden Using a Modeling Approach

Objective: To evaluate the precision of the predictive cost-effectiveness assessment based on a phase 3 clinical trial with infliximab for the treatment of rheumatoid arthritis in Swedish clinical practice. Methods: Three patient cohorts were identified: the patients included in the infliximab trial (ATTRACT), patients initially treated with infliximab from a Swedish registry (STURE), a subset of

Assessing above-ground woody debris dynamics along a gradient of elevation in Amazonian cloud forests in Peru: balancing above-ground inputs and respiration outputs

Background: Dead biomass, including woody debris (WD), is an important component of the carbon cycle in tropical forests. Aims: This study analyses WD (>2 cm) and other above-ground fluxes in mature tropical forest plots along an elevational gradient (210-3025 m above sea level) in southern Peru. Methods: This work was based on inventories of fine and coarse WD (FWD and CWD, respectively), above-g

Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party

To specify the incidence and risk factors for secondary autoimmune diseases (ADs) after HSCT for a primary AD, we retrospectively analyzed AD patients treated by HSCT reported to EBMT from 1995 to 2009 with at least 1 secondary AD (cases) and those without (controls). After autologous HSCT, 29 of 347 patients developed at least 1 secondary AD within 21.9 (0.6-49) months and after allogeneic HSCT,