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Climate change is affecting all regions of the globe, causing a shift of temperature distributions. As species try to track their optimal thermal conditions, they are also potentially met with new photic environments. Photoperiod is the main cue for synchronizing migratory birds' circannual rhythms, affecting both their physiology and migration. Thus, their ability to incorporate and adjust to

To examine longitudinal trajectories of pain occurrence in children with cerebral palsy (CP) aged 1 year to 17 years.A longitudinal register-based study was conducted using data from the Swedish Cerebral Palsy Follow-up Program (2007-2023). Individuals (n = 4887) with confirmed CP, a minimum of three pain assessments, and any Gross Motor Function Classification System (GMFCS) levels were included

AIMS: While workplace wellness services are proactively established to improve well-being and reduce sickness absence, knowledge of reasons for using these services remains sparse. This study investigates which factors determine use of an in-house wellness service at a large organization (the Danish Police) with several departments in different geographical locations.METHODS: All potential users o

Background: Corynebacterium species are often dismissed as contaminants in blood cultures, but they can also cause infective endocarditis (IE), which is a severe condition. Antibiotic resistance of corynebacteria is increasing making treatment challenging. Reports on IE caused by Corynebacterium species are scarce and more knowledge is needed. Methods: Cases of IE caused by Corynebacterium species

BACKGROUND: Oesophageal cancer management requires extensive in-hospital care. This cohort study aimed to quantify in-hospital care for patients with oesophageal cancer in relation to intended treatment, and to analyse factors associated with risk of spending a large proportion of survival time in hospital. METHODS: All patients with oesophageal cancer in three nationwide registers over a 10-year

Objective: To describe the epidemiology of injuries and illnesses sustained during the Beijing 2022 Paralympic Winter Games, organised in a closed-loop environment to adhere with COVID-19 restrictions. Methods: Injuries and illnesses from all teams were recorded on a daily basis by team medical staff on a web-based form and by local organising committee medical (polyclinic) facilities and venue me

The design of iron complexes with long-lived charge transfer states suitable for applications as photosensitizers remains a formidable challenge. Here, we investigated the effect of an extended ligand π-system on the ground- and excited-state properties of iron(II) complexes with N-heterocyclic carbene (NHC) ligands. For this purpose, three iron complexes based on the established [Fe(II)(pbmi)2]2+

Study objectives: The aim of this study was to develop quality criteria for further development and use in the Medicines Management(MM) process in European hospitals. Methods: Criteria for MM were developed in three steps using a modified two-stage Delphi-technique. In the first step a literature search was performed and 300 topics were listed. These topics were grouped into three dimensions, e

Lactobacillus reuteri is known as probiotics with health benefits. Freeze-drying is frequently used to preserve probiotics and keep them alive. However, freeze-drying through freezing and drying might cause some damages to the probiotic’s cells. Formulation by protective agents including cryoprotectants and lyoprotectants prior to freeze-drying can prevent and reduce these damages. In this study,

Helicobacter pylori is an important pathogen inhabiting the human stomach. H. pylori binds plasminogen, a 90 kDa glycoprotein secreted by liver cells, and utilizes it for enhancing virulence. Surface receptors on the bacteria recognize plasminogen that is then activated into plasmin by host factors. The active plasmin can degrade a range of host proteins including proteins of the extracellular mat

Purpose: To investigate the incidence and risk factors of retinal detachment (RD) and bacterial endophthalmitis in a cohort of children who underwent cataract surgery before the age of eight. Methods: Data was retrieved from the Swedish national paediatric cataract register. All eyes with congenital or infantile cataract that underwent surgery between January 1, 2007, and December 31, 2023 with at

Food safety is a public health concern worldwide due to an increased morbidity and mortality risk associated with the outbreak of food-borne diseases. This study aimed to assess knowledge, attitude, and food safety practices (KAP) among university students in northern Tanzania. This is interesting because it allows data to be collected for creating awareness on safety, sanitation, and quality of f

Background and Aims: In primary sclerosing cholangitis (PSC), the risk for gallbladder malignancy is increased. Surveillance imaging is used for early diagnosis. The study aims to assess the reliability of ultrasound and magnetic resonance imaging (MRI) for the detection of gallbladder polyps in people with PSC and to define a polyp size as a cut-off at which cholecystectomy is indicated due to th

BACKGROUND: Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cancer. The aim of this analysis was to identify genetic variants that are associated with urinary sex-hormone levels and breast cancer risk.METHODS: We carried out a genome-wide association study of urinary oestrone-3-glucuronide and pregnanediol-3-glucuronide levels in 560

Introduction: Data regarding real-world impact on cancer clinical research during COVID-19 are scarce. We analysed the impact of the COVID-19 pandemic on the conduct of paediatric cancer phase I–II trials in Europe through the experience of the Innovative Therapies for Children with Cancer (ITCC). Methods: A survey was sent to all ITCC-accredited early-phase clinical trial hospitals including ques

Background The prognostic value of blood lactate as a predictor of adverse outcome in the acutely ill patient is unclear. The aim of this study was to investigate if a peripheral venous lactate measurement, taken at admission, is associated with in-hospital mortality in acutely ill patients with all diagnosis. Furthermore, we wanted to investigate if the test improves a triage model in terms of pr

Background: Approximately 80% of soft tissue sarcoma (STS) recurrences, local and metastatic disease, are diagnosed within the first 3 years after primary diagnosis and treatment. Recurrences, however, can present after a longer period of remission. Our goal was to identify factors that may predict the risk of late recurrence. Methods: We identified 677 patients with STS of the extremities and tru