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Cross-Ancestry DNA Methylation Marks of Insulin Resistance in Pregnancy : An Integrative Epigenome Wide Association Study

Although there are some epigenome-wide association studies (EWAS) of insulin resistance, most of them did not replicate their findings and are focused in populations of European ancestry limiting the generalizability. In EPIPREG (294 Europeans and 162 South Asians), we conducted an EWAS of insulin resistance in maternal peripheral blood leukocytes, with replication in Born in Bradford (n=879; 430

The role of poly(ethyleneimine) in stabilization against metal-catalyzed oxidation of proteins: a case study with lactate dehydrogenase.

The protection provided by poly(ethyleneimine) (PEI) to muscle lactate dehydrogenase (LDH) in metal-catalyzed oxidation (MCO) systems (CuSO(4) or FeCl(2) combined with H(2)O(2)) was studied, and comparisons were made with the chelators EDTA and desferal, respectively. The analytical chelating capacity of PEI was estimated to be around 1 mol Cu(2+)/10 mol ethyleneimine for all molecular weights of

Thermodynamic and kinetic aspects on water vs. organic solvent as reaction media in the enzyme-catalysed reduction of ketones

The stereoselective reduction of ketones catalysed by alcohol dehydrogenase from Thermoanaerobium brockii was studied in different reaction media, hexane at controlled water activities, hexane with 2.5% water (biphasic) and pure water. The reactions were studied in the temperature range from -1 to 50°C. Increasing the water activity from 0.53 to 0.97 increased the reaction rate 16-fold. The rate w

SIX1 as a Novel Immunohistochemical Marker in the Differential Diagnosis of Rhabdomyosarcoma

Background: Differential diagnosis of rhabdomyosarcoma (RMS) is challenging. Sineoculis homeobox homolog 1 (SIX1) is an oncogene involved in skeletal muscle differentiation. We compared protein expression patterns of SIX1 in RMS and its most common differential diagnoses. Methods: SIX1 immunohistochemistry in 36 RMS and in 33 tumors from seven differential diagnostic subtypes were evaluated. The f

Blyföroreningar på skjutbanor i Lunds kommun

Lead was an essential part of bullets used at shooting ranges in Sweden. This has lead to that many shooting ranges have elevated amounts of lead in the soil, ie. lead ground contamination. As lead causes severe health effects on humans and animals, and accumulates in the nature then this is of great concern. This contamination and its effects on humans is also very important since many of those s

Ämnet smärta i den svenska sjuksköterskeutbildningen

All vårdpersonal bör ges grundläggande kunskaper om smärtsinnet, reaktioner på smärta samt behandling av olika typer av smärta. Sjuksköterskor ska dessutom ha god kännedom om tekniker för smärtskattning, om psykologiska faktorers betydelse och om traditionella smärtstillande läkemedels kliniska användning (SoS-rapport 1994:4). Syftet med denna studie var att undersöka förekomst, innehåll och mål f

Nya fynd i aggressiv spädbarnsleukemi – Vetenskap och Hälsa

Nya fynd i aggressiv spädbarnsleukemi – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Nya fynd i aggressiv spädbarnsleukemi 2018-05-21 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Akut lymfatisk leukemi (ALL) hos spädbarn under ett år, är en ovanlig sjukd

https://www.vetenskaphalsa.se/nya-fynd-i-aggressiv-spadbarnsleukemi/ - 2026-05-08

Contact allergy from disperse dyes in textiles-a review.

Several disperse dyes (DDs) are still considered to be the most important allergens in textile dermatitis, but there are sparse data about their current use in textiles. The aim of this review was to evaluate published studies and reports on contact allergy to DDs published in PubMed during the last 22 years (1990-2012). Prevalence data are provided by study and by dye, as well as by the described

Moisture equilibrium of cement based materials containing slag or silica fume and exposed to repeated sorption cycles

Water vapor sorption isotherms are essential data in models to predict the service life of cement based structures. This study investigates the influence of water to binder ratio (0.4, 0.5 and 0.6), and the presence of two SCMs (70% slag and 10% silica fume) on sorption isotherms, both in the hygroscopic and in the super-hygroscopic relative humidity (RH) ranges. In the present paper desorption is

Underestimation of toluene diisocyanate concentration using long-term sampling with 1-(2-methoxyphenyl) piperazine impregnated filters.

Occupational exposure to toluene diisocyanate (TDI) is a known occupational hazard and the occupational exposure limits in air are very low. One of the most common methods to monitor exposure to isocyanates is to sample air through filters impregnated with 1-(2-methoxyphenyl) piperazine (2MP). In one earlier field study it was found that long-term sampling with 2MP-filters underestimated the expos

Contact allergy from disperse dyes in textiles-a review.

Several disperse dyes (DDs) are still considered to be the most important allergens in textile dermatitis, but there are sparse data about their current use in textiles. The aim of this review was to evaluate published studies and reports on contact allergy to DDs published in PubMed during the last 22 years (1990-2012). Prevalence data are provided by study and by dye, as well as by the described

A22

Microsoft Word - Afrint II Ghana micro report.doc June 2009 Afrint II: Ghana Draft Micro and Meso Study report ii Afrint II: Ghana Micro and Meso Study Report Contents  CHAPTER 1 ...................................................................................................................... 1  BACKGROUND TO THE STUDY ...........................................................................

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/a22.pdf - 2026-05-09

Exploring the influences of a low-income neighbourhood environment on children's physical activity in China

Background: This study aimed to explore how the physical and social environment of a neighbourhood influenced the physical activity of children from the perspective of children and caregivers. It used a low-income neighbourhood in Beijing as the setting and focused on children in middle childhood. Methods: Guided by the Urban Ecological Model for Environment and Health Behaviour, semi-structured i