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A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1
Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of childhood acute lymphoblastic leukemia (ALL). To identify new susceptibility loci for the largest subtype of ALL, B-cell precursor ALL (BCP-ALL), we conducted a meta-analysis of two GWASs with imputation using 1000 Genomes and UK10K Project data as reference (totaling 1658 cases an
Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a
Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr
Birth outcomes between 22 and 26 weeks' gestation in national population-based cohorts from Sweden, England and France
Short half-life of HPV16 E6 and E7 mRNAs sensitizes HPV16-positive tonsillar cancer cell line HN26 to DNA-damaging drugs
Bicyclo[3.3.1]nonane-2,6-dione and its utilization as a core building block in supramolecular architectures
Influence of the mannan binding module of beta-mannanase CfMan26A in the hydrolysis of mannan
Hemicellulose is next to cellulose the most abundant polysaccharide on earth and as such an important renewable resource. Mannans are the major hemicellulose in so:ftwodd and are found as storage polysaccharide in various plants. -mannanases are the main mannan degrading enzymes. In this work the -1,4-mannanase from the soilliving bacteria Cellulosamas Jimi was studied and special focus was put on
Influence of morphological and conformational changes on the molecular mobility in poly(ethylene naphthalene-2,6-dicarboxylate)
Array based characterization of a terminal deletion involving chromosome subband 15q26.2: an emerging syndrome associated with growth retardation, cardiac defects and developmental delay.
BACKGROUND: Subtelomeric regions are gene rich and deletions in these chromosomal segments have been demonstrated to account for approximately 2.5% of patients displaying mental retardation with or without association of dysmorphic features. However, cases that report de novo terminal deletions on chromosome arm 15q are rare. METHODS: In this study we present the first example of a detailed molecu
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk
The possibility of lifestyle and biological risk markers to predict morbidity and mortality in a cohort of young men after 26 years follow-up.
The Impact of Quadrivalent Human Papillomavirus (HPV; Types 6, 11, 16, and 18) L1 Virus-Like Particle Vaccine on Infection and Disease Due to Oncogenic Nonvaccine HPV Types in Generally HPV-Naive Women Aged 16-26 Years
An Improved Procedure for the Synthesis of Bicyclo[2.2.2]octane- 2,6-dione
A combined experimental and theoretical study of uranium polyhydrides with new evidence for the large complex UH4(H-2)(6)
Several monouranium and diuranium polyhydride molecules were investigated using quantum chemical methods. The infrared spectra of uranium and hydrogen reaction products in condensed neon and pure hydrogen were measured and compared with previous argon matrix frequencies. The calculated molecular structures and vibrational frequencies were used to identify the species present in the matrix. Major n
Comparison of growth characteristics and exopolysaccharide formation of two lactic acid bacteria strains, Pediococcus damnosus 2.6 and Lactobacillus brevis G-77, in an oat-based, non-dairy medium.
Tumor attenuation by 2(6-hydroxynaphthyl)-{beta}-D-xylopyranoside requires priming of heparan sulfate and nuclear targeting of the products.
2,6-Bis(5,6-dicyclohexyl-1,2,4-triazin-3-yl)-pyridine-dichloromethane-wa ter (1/1/0.625)
A 26-GHz LC-QVCO in 0.13-um CMOS
The synthesis of bicyclo[2.2.2]octan-2,6-dione revisited
A Fully Integrated 26dBm Linearized RF Power Amplifier in 65nm CMOS Technology
In this paper, design and measurements of a fully integrated power amplifier (PA) are presented. The PA consists of two amplifying chains each having a driver and a power stage. A low loss on chip power combiner combines the outputs from two amplifying chains, and also performs impedance transformation and differential to single-ended conversion. To linearize the PA, the driver stage is biased in
