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Background Cell and animal experiments have shown that beta-site APP-cleaving enzyme 1 (BACE1) may be involved in myelination. Objective Here, we assess the association of cerebrospinal fluid (CSF) BACE1 activity with multiple sclerosis (MS). Methods BACE1 activity and levels of secreted amyloid precursor protein (APP) and amyloid-beta (A beta) isoforms were analyzed in CSF from 100 patients with
The human DUSP15 gene encodes an uncharacterized 235-amino acid member of the subfamily of small dual specificity protein phosphatases related to the Vaccinia virus VH1 phosphatase. Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2. In reco
The transglucosylation reaction catalyzed by wild-type β-glucosidase CelB from hyperthermophilic Pyrococcus furiosus and active site mutants (M424K, F426Y, M424K/F426Y) was studied. The conversion of pentyl-β-glucoside to hexyl-β-glucoside in hexanol was used as a model transglucosylation reaction. Hydrolysis to glucose was a side reaction. The activity (rates of hydrolysis and transglucosylation)
Substrate properties can affect the thermal balance of organisms, and the colored integument, alongside other factors, may influence heat transfer via differential absorption and reflection. Dark coloration may lead to higher heat absorption and could be advantageous when substrates are cool (and vice versa for bright coloration), but these effects are rarely investigated. Here, we examined the ef
THE LITTLE STINT Calidris minuta is an Arctic wader species that migrates through the Baltic Sea region towards wintering areas in North and West Africa and the Mediterranean region. We use a 75-year trapping series, comprising 4,791 Little Stints on autumn migration, from Ottenby Bird Observatory in Sweden to illustrate long-term trends in abundance, phenology, and morphometrics. Numbers of trapp
Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food
BACKGROUND: Atrial septal pacing (ASP) has been shown to shorten P-wave duration (PWD) and reduce recurrence of atrial fibrillation (AF) in patients with bradyarrhythmias. However, variability of interatrial connections and atrial conduction properties may explain ASP's modest clinical benefit. The aim of this study was to assess the effect of ASP site on the duration of the paced P wave. METHODS
Great Spotted and Syrian Woodpeckers (Dendrocopos major and D. syriacus) are known to hybridize in nature; however, the extent of this phenomenon is not known due to difficulties in hybrid detection based on plumage analyses. Here, we tested five markers (one mitochondrial and four nuclear) and a set of six microsatellite loci for the identification of these two Woodpeckers and their hybrids. Sequ
The primary objective was to estimate serum thymidine kinase 1 (TK1) activity, reflecting total body cell proliferation rate including cancer cell proliferation, in women with loco regional inoperable or metastatic breast cancer participating in a prospective and randomized study. Secondary objectives were to analyze TK1 in relation to progression-free survival (PFS), overall survival (OS), therap
The Italian Sarcoma Group and the Scandinavian Sarcoma Group designed a joint study to improve the prognosis for patients with Ewing's family tumors and synchronous metastatic disease limited to the lungs, or the pleura, or a single bone. The study was opened in 1999 and closed to the enrollment in 2008. The program consisted of intensive five-drug combination chemotherapy, surgery and/or radiothe
Professor of Fine Arts Contact details Email: joachim [dot] koester [at] khm [dot] lu [dot] seOrganisation Malmö Art Academy WebpageJoachim Koesters profile in Lund University research portalJoachim Koester is a Danish artist based in Copenhagen. His work has been shown at documenta X, Kassel; 2nd Johannesburg Biennale; Gwangju Biennale 1995; 54th Venice Biennale; Busan Biennale 2006; Manifesta 7
https://www.khm.lu.se/en/joachim-koester - 2026-05-29
Shiga toxin (Stx), the unique virulence factor released by enterohemorrhagic Escherichia coli (EHEC), associated with gastrointestinal infection and in severe cases hemolytic uremic syndrome (HUS). Up until now, no effective therapies have been developed to control disease progression. In this thesis, four novel treatment strategies have been investigated targeting different aspects of EHEC pathog
Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article
Kursplaner ENG NGE006F, Hydrogeological Conceptual Models for Groundwater Use and Protection. Characterisation methods and scaling considerations, 4.5 credits Konceptuella hydrogeologiska modeller för tillämpningar inom och skydd av grundvatten. Karakteriseringsmetoder med hänsyn till olika skalor, 4,5 högskolepoäng Third Cycle/Forskarnivå __________________________________________________________
https://www.geology.lu.se/sites/geology.lu.se/files/2023-01/NGE006F%20Hydrogeological%20Conceptual%20Models_ENG.pdf - 2026-05-30
FOLDER 3 Universitetsbibliotekets utställningskatalog 63 28 Universitetsbiblioteket, Lunds universitet Box 3, 221 00 LUND UB Media. ISSN 0281-3823, LULID/LIBR - 1551 9 december 2011 - 22 april 2012 Universitetsbiblioteket i Lund fick 2007 ta emot en säll- sam och ovanligt spännande donation från Berit Harrison i Klörup. Hennes make direktör Bertil Harrison köpte redan som 10-åring sin första bok o
https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2011_duvbibliotek.pdf - 2026-05-30
Kursguide - Course Syllabus • • • Fastställande Kursplanen är fastställd av Styrelsen för institutionen för service management och tjänstevetenskap 2017-11-29 att gälla från och med 2018-01-01, vårterminen 2018. Allmänna uppgifter Kursen ingår i Kandidatprogrammet för service management och är den andra av två inriktningsspecifika kurser inom inriktningen tourism & hotel management på andra termin
https://www.ses.lu.se/sites/ses.lu.se/files/kp_ksma27_171129.pdf - 2026-05-30
