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Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4.

OBJECTIVE: Mapping coreceptor epitopes used by the prototypic R5 and X4 strains, HIV-1BaL and HIV-1IIIB, in comparison with epitopes involved in the activation and signaling induced by the natural ligands, RANTES and SDF-1beta. DESIGN: Receptor hybrids between CCR5 and CXCR4 were constructed. METHODS: Using single-overlap and extension PCR, increasing portions of CCR5 were replaced with correspond

Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML

Understanding leukemia heterogeneity is critical for the development of curative treatments as the failure to eliminate therapy-persistent leukemic stem cells (LSCs) may result in disease relapse. Here we have combined high-throughput immunophenotypic screens with large-scale single-cell gene expression analysis to define the heterogeneity within the LSC-population in chronic phase chronic myeloid

Serum Complement Activation by C4BP-IgM Fusion Protein Can Restore Susceptibility to Antibiotics in Neisseria gonorrhoeae

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

GAD65 autoantibodies (GAD65Ab) are highly prevalent in type 1 diabetes, but their functional role in the pathogenesis of the disease and their relationship to T-cell reactivity to GAD65 is still unclear. We tested the hypothesis that GAD65Ab modulate presentation of GAD65 to T-cells. T-cell hybridoma T33.1, which recognizes the GAD65 274-286 epitope in the context of HLA-DRB1*0401, was incubated w

Dietitian visits were a safe and cost-effective form of follow-up care for children with celiac disease

Aim: This study compared follow-up protocols for paediatric celiac disease (CD) led by either paediatricians or dietitians at Swedish university hospitals. Methods: We followed 363 CD patients under 18 years at the university hospitals in Malmö (n = 140) and Lund (n = 79) between 2011 and 2013 and after they merged to become Skåne (n = 144) between 2014 and 2016. Both Lund and Malmö provided regul

Experiments and Large Eddy Simulation of Supersonic Combustion in the Small-Scale Flight Experiment

Supersonic combustion is a critical area of research for advancing high-speed flight technologies, particularly for the development of scramjet engines for hypersonic vehicles. This study employs Finite Rate Chemistry (FRC) Large Eddy Simulation (LES) together with different experimental techniques to study the supersonic flow and thermochemical processes in the Small Scale Flight Experiment (SSFE

Production and Functional Characterization of Der p 1-Specific Human Recombinant IgE

Ny forskning bidrar till ökad förståelse av allergiska reaktioner Allergi har ökat dramatiskt under de senaste åren. Det är därför högst väsentligt att få ökad kunskap om hur beståndsdelarna i immunförsvaret hos allergiska personer samspelar. Förekomsten av allergi har kommit att öka dramatiskt under de senaste åren och har blivit ett betydande problem för folkhälsan. Allergi drabbar en så stor dThe prevalence of allergic disease is continuing to increase worldwide, and it has even become a major concern in public health. Allergic reactions are developed to otherwise harmless substances and may be both life-threatening as well as discomforting for patients in their daily life. Therefore, a more detailed knowledge about how antibodies interact with allergens and effector cells in allergic

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FRAF21 Franska: Grundkurs i Frankrike Semestre d’automne 2025 Hitta (student)boende i Toulouse Trouver un logement (étudiant) à Toulouse Detta dokument är tänkt som ett stöd för de studenter från Lunds universitet som kommer att åka till Université de Toulouse Jean Jaurès för att läsa franska under höstterminen 2025. Dokumentet innehåller information om hemsidor och länkar som hjälper er att komma

https://www.sol.lu.se/fileadmin/user_upload/sol/aemnen/sektion3/Logement_%C3%A9tudiant_%C3%A0_Toulouse_HT2025.docx - 2026-05-28

Ida Scherman

Forskningsadministratör Kontaktinformation E-post: ida [dot] scherman [at] fysik [dot] lu [dot] se Telefon: +46 46 222 76 72 Mobil: +46 72 219 72 84Organisation Fasta tillståndets fysik Besöksadress: Professorsgatan 1, Lund Rumsnummer: C364B Hämtställe: 14 WebbplatsIda Schermans profil i Lunds universitets forskningsportalAndra roller Doktorand Mänskliga rättigheter Medlem i Strategiskt forsknings

https://www.fysik.lu.se/ida-scherman - 2026-05-29

Riktlinjer-for-nyttjande-av-genetiska-resurser-och-eller-traditionell-kunskap

Riktlinjer för nyttjande av genetiska resurser och/eller traditionell kunskap FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer för nyttjande av genetiska resurser och/eller traditionell kunskap Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Riktlinjer fastställer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska- regel ska följas medan en bör-regel mer har kara

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2024-10/Riktlinjer-for-nyttjande-av-genetiska-resurser-och-eller-traditionell-kunskap.pdf - 2026-05-29

Direct hospital costs of chest pain patients attending the emergency department: a retrospective study

BACKGROUND: Chest pain is one of the most common complaints in the Emergency Department (ED), but the cost of ED chest pain patients is unclear. The aim of this study was to describe the direct hospital costs for unselected chest pain patients attending the emergency department (ED). METHODS: 1,000 consecutive ED visits of patients with chest pain were retrospectively included. Costs directly foll

Introducing brief admissions by self-referral in child and adolescent psychiatry : an observational cohort study in Sweden

BACKGROUND: Brief admission by self-referral, a novel crisis intervention designed to reduce suicide and self-harm in adults, was adopted for adolescents in paediatric psychiatry in Malmö, Sweden, in 2018. We aimed to investigate changes in utilisation of emergency psychiatric care.METHODS: We did an observational longitudinal cohort study in The University Hospital in Malmö, Sweden, which provide

Gästforskarprogram

Gästforskare är en viktig del av Rättssociologiska institutionens verksamhet och vi strävar efter att integrera våra besökare i det intellektuella och sociala livet på institutionen och Lunds universitet. Vi erbjuder alla gästforskare en arbetsplats i ett delat kontor med internetuppkoppling. Du har tillgång till universitetsbiblioteken samt möjlighet att delta i seminarier, föreläsningar och work

https://www.soclaw.lu.se/forskning/gastforskarprogram - 2026-05-29