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In Parkinson’s disease, long-term dopamine replacement therapy is complicated by the appearance of L-DOPA-induced dyskinesia (LID). One major hypothesis is that LID results from an aberrant transcriptional program in striatal neurons induced by l-DOPA and triggered by the activation of ERK. To identify these genes, we performed transcriptome analyses in the striatum in 6-hydroxydopamine-lesioned m
Background: Stress ulcer prophylaxis (SUP) may decrease the incidence of gastrointestinal bleeding in patients in the intensive care unit (ICU), but the risk of infection may be increased. In this study, we aimed to describe SUP practices in adult ICUs. We hypothesised that patient selection for SUP varies both within and between countries. MethodsAdult ICUs were invited to participate in the surv
As an approach to determining the aetiology of chronic lymphocytic leukaemia (CLL), we searched for a virus expressed in human CLL B-cells by combining high-throughput sequencing and digital subtraction. Pooled B-cell mRNA transcriptomes from five CLL patients and five healthy donors were sequenced with 454 Life Sciences technology. Human reads were excluded by BLAST (Basic Local Alignment Search
In this study, we examined the onset and duration of local analgesic effects of bupivacaine incorporated into biodegradable microcapsules (extended-duration local anesthetic; EDLA) administered as subcutaneous infiltrations in different doses in humans. In 18 volunteers, the skin on the medial calf was infiltrated with 10 mL of EDLA, and the opposite calf was infiltrated with 10 mL of aqueous bupi
Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation
PUFA from oil extracted from Nile perch viscera were enriched by selective enzymatic esterification of the free fatty acids (FFA) or by hydrolysis of ethyl esters of the fatty acids from the oil (FA-EE). Quantitative analysis was performed using RP-HPLC coupled to an evaporative light scattering detector (RP-HPLC-ELSD). The lipase from Thermomyces lanuginosus discriminated against docosahexaenoic
The effect of deglycosylation of pyranose dehydrogenase (PDH) obtained from Agaricus meleagris (Am) and recombinantly expressed in Pichia pastoris on its electrocatalytic activity was investigated. Glycosylated (gAmPDH) and deglycosylated PDH (dgAmPDH) were immobilised on spectrographic graphite (G) simultaneously with an osmium redox polymer (Os-RP) using poly(ethylene glycol)(400) diglycidyl eth
The myeloid translocation gene 16 product MTG16 is found in multiple transcription factor-containing complexes as a regulator of gene expression implicated in development and tumorigenesis. A stable Tet-On system for doxycycline-dependent expression of MTG16 was established in B-lymphoblastoid Raji cells to unravel its molecular functions in transformed cells. A noticeable finding was that express
Transposition of intestinal segments is frequently used for bladder reconstruction. Following transposition, bowel segments continue to produce mucus and a correlation between excessive mucus production and complications such as urinary tract infection or catheter blockage has been observed for a long time. However, no information is currently available on the change of mucin expression and glycos
We reported that high estrogen receptor beta (ERβ) expression is independently associated with better prognosis in female colorectal cancer (CRC) patients. However, estrogen receptor alpha (ERα) is expressed at very low levels in normal colon mucosa, and its prognostic role in CRC has not been explored. Herein, we investigated the combined role of ERα and ERβ expression in the prognosis of female
Hybridization can result in novel allelic combinations which can impact the hybrid phenotype through changes in gene expression. While misexpression in F1 hybrids is well documented, how gene expression evolves in stabilized hybrid taxa remains an open question. As gene expression evolves in a stabilizing manner, break-up of co-evolved cis- and trans-regulatory elements could lead to transgressive
EXCHANGE STUDIES EXCHANGE STUDIES LUUP HANDBOOK FOR APPLICATIONS 2012/2013 Photo: Ylva Kalin, exchange student in Santiago, Chile 1 Your opportunities……………………………………………………………………………. 2 Admission requirements.…………………………...................................................... 3 Faculty-specific admission requirements ……………………………………………… 3 Preparation…………………………………………………………………………………… 4 Get started early!..
https://www.lu.se/sites/www.lu.se/files/luupinenglish_12_13.pdf - 2026-07-25
This page lists pasts talks at the CBBP seminars (2002 to 2023). The Computation Biology and Biological Physics group is now part of COSHE. See the calendar for future and recent COSHE seminars.2023Nov 08: Andreas Nilsson and Jesper Sjolte, GeologySynchronising and synthesising paleo data with chronologic uncertaintiesOct 30: Dmytro Perepolkin, CECIntroduction to Bayesian Parametric Quantile Regre
https://www.cec.lu.se/research/research-themes/computational-science-health-and-environment/past-cbbp-seminars - 2026-07-23
We offer a number of bachelor's and master's level stand-alone courses in english within the subject of Service management. Stand-alone courses (bachelor's level) Risk and Crisis Management, 7,5 credits SyllabusReading list Schedule (will be available late spring 2026)Study period: August 31 - September 29, 2026The course is taking place at Campus HelsingborgRead more about the course on lunduniv
https://www.ses.lu.se/en/education/stand-alone-courses - 2026-07-23
On this page, you will find answers to frequently asked questions about digital monitoring. Is the University allowed to monitor me as a student when I undertake a specific examination task? Yes, monitoring is allowed if the teacher can motivate the necessity of it to ensure a legally secure examination. As a student, information about monitoring should be given to you well in advance of your exam
https://www.campusonline.lu.se/en/digital-exam-monitoring/faq-about-digital-monitoring - 2026-07-23
NGEN20 The course is a compulsory course at second cycle level for a Degree of Master of Science (120 credits) in GIS and remote sensing in the main field of study geomatics and an elective course for a Degree of Master of Science in Physical Geography and Ecosystem Sciences. Course content On completion of the course, you should have acquired knowledge to handle the programming language Python to
https://www.nateko.lu.se/NGEN20 - 2026-07-23
