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Tattoo exposure and biomarkers of male fecundity : A cross-sectional study among young Danish males

Background: Tattoo inks are mixtures of organic and inorganic color pigments and having a tattoo may be adversely associated with biomarkers of male fecundity. Objective: To examine the association between tattoo exposure and biomarkers of male fecundity. Methods: Participants were young adult Danish males (aged 18–21 years) sampled from the Danish National Birth Cohort. Upon recruitment in 2017–2

The Relative Importance of Fecal and Urinary Excretion of Perfluorooctane Sulfonic Acid and Perfluorooctanoic Acid after High Exposure - An Observational Study in Ronneby, Sweden

BACKGROUND: Many poly- and perfluoroalkyl substances (PFAS) are persistent and have long half-lives in the human body. However, there are limited data on the different routes of elimination. Most pharmacokinetic models assume that the urinary route dominates.OBJECTIVES: Our aim was to investigate the relative importance of fecal and urinary elimination for linear perfluorooctane sulfonic acid (L-P

“This is something we live through every day” : negotiating the cultural memory of the Decembrist revolt in Russian historical film Union of Salvation

The study examines the narratives of the Decembrist revolt created in and around Russian state-funded cinema. By exploring the narratives surrounding a particular instance of political dissent in the past, the research seeks to uncover the factors that impact on the negotiation of cultural memory between the text and the audience in the context of state-influenced media. This exploration is based

Hip dysplasia as risk factor for clinically relevant and radiographic hip osteoarthritis : 10-year results from the CHECK cohort

OBJECTIVES: To investigate hip dysplasia as a risk factor for clinically relevant and incident radiographic hip OA.METHODS: From a prospective cohort (CHECK) of 1002 middle-aged, new consulters for hip and/or knee pain, 468 hips (251 individuals) were selected based on hip pain, available lateral center edge angle (LCEA) and absence of definite radiographic hip OA (Kellgren and Lawrence [KL] grade

Risk of preeclampsia and gestational diabetes after occupational exposure to chemicals during pregnancy–A cohort study of births in Sweden 1994–2014

Many women are occupationally active during pregnancy. The aim of this study was to investigate associations between exposure to chemicals during pregnancy and the risk of gestational diabetes or preeclampsia. The cohort included singleton births in Sweden between 1994 and 2014. The cohort was limited to low-educated mothers to reduce potential confounding from unidentified life-style associated f

Mechanical chest compressions for cardiac arrest in the cath-lab : When is it enough and who should go to extracorporeal cardio pulmonary resuscitation?

Background: Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and more aggressive treatment modalities, including extracorporeal CPR are becoming more common. The cath-lab setting enables monitoring of vital physiological parameters and other clini

Rethinking TNM : Tumor deposit-based prognostic models may improve N-staging in colorectal cancer

Introduction: Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel progn

Det ser inte passande ut! : om kvinnors alkoholkonsumtion och kvinnorollens påverkan av densamma

The first aim of this study was to on historical background survey women's alcohol habits and especially to investigate women aged 50-59 living in the Lund area. The second aim was to increase the understanding of how women's sex role has a restrictive influence on their alcohol habits. To investigate women's alcohol habits I made two quantitative studies. From secondary data I found t

New anticancer drugs in Sweden

Previous studies have found that launch prices reflect the therapeutic gains of pharmaceuticals (for instance: Ekelund and Persson, 2003, on Sweden and Lu and Comanor, 1998, on the US). Furthermore, Howard et al (2015) found that purely pharmaceutical costs to “Medicare” at launch for new anticancer drugs increased annually, from 1995-2013, after controlling for health benefits and inflation. This

An AFFIRM Assay for Potential Biomarkers in Relapsed Breast Cancer

Relapsed or recurrent breast cancer is the chief cause of breast cancer related deaths and it is estimated that one-third of breast cancer patients would likely suffer a relapse. Due to high mortality and incidence, recurrent breast cancer requires better means of prediction, prevention and treatment. The AFFIRM platform uses recombinant antibody technology and selected reaction monitoring (SRM) m

Generation of a statistical model of the anatomy of human pelvises

3D-modell av höftbenet kan hjälpa till att förutspå artros Det är viktigt att förebygga sjukdomar innan de bryter ut. Vanliga 2D-röntgenbilder är inte alltid tillräckligt noggranna men med 3D-modeller kan tidiga tecken på artros lättare identifieras. Vi strävar för att få fram 3D-bilder av höften från vanliga röntgenbilder.Osteoarthritis and osteoporosis are two medical conditions involving the hip which affect the life quality of many people worldwide. These two diseases are diagnosed with 2D imaging by analysis of radiological measures, bone mineral density and joint space. Computed Tomography (CT) can provide 3D images of the hip, but has higher cost and imposes a higher radiation dose to the patient. Another op

Reduction of Microorganisms in liquids by UV light, a prototype test

Reducing microorganisms by UV light is has been commonly used for drinking water for many years. In other liquid products like apple juice it is a rather novel application. The advantages would be that quality parameters like aromas and vitamins are less affected by the UV treatment compared to a heat treatment. Furthermore it would probably be cheaper, as the lamps need less electrical energy tha

Testing the International Standards Organization Verification and Validation protocol for evacuation simulations-An application to the FDS+Evac model

Nowadays, many evacuation models exist in the market, and new models are continuously released with new features. How to assess the usability and reliability of model results becomes an issue for both developers and users. Therefore, verification and validation (V&V) protocols were introduced in the assessment process of evacuation models. To conduct V&V of a model, a widely accepted test

Spinning facts. Of spin, post-truth and the instrumentalisation of science. A case study from Denmark

Connecting science to political agenda-setting is essential for a sustainable transition and acceptable politics. This task is complicated by phenomena like post-truth, for which facts are a non-issue. However, post-truth is not the only issue. The practice of political spin, in which the significance of facts is reconstructed according to specific interests poses another threat to scientific cred

The need to focus on plastic in terrestrial environments: Do micro- and nanoplastic affect microorganisms in soil?

Fokus på plast i mark och jord: mikroplasters effekt på organismer i jord undersökt med ny teknologi inom jordekologi frågor. De enorma plastutsläppen till naturen är idag ett välkänt problem. Det är också välkänt att plast bryts ner till mindre partiklar med andra effekter, så kallade mikro- och nanoplaster. Allmänheten har visat stort intresse kring plastproblematiken i haven och mycket forskniThis study aims to investigate if micro- and nanoparticles of polystyrene affect microorganisms in soil. This was tested by using microfluidic chips, which are new for investigation of soil ecology questions, providing artificial channels reflecting soil conditions as well as being transparent for seeing real-time interactions. Eight microfluidic chips were made; four were filled with a micro- and

Markanvändning vid byggnation av höghastighetsjärnväg; en jämförelsestudie mellan höghastighetsjärnväg på bank och höghastighetsjärnväg på viadukt.

In the construction of high-speed railways, an important starting point is to make as little Intrusion on land as possible, therefore it is of high importance to carefully investigate which construction alternatives are the most advantageous. The purpose of this work is to compare and evaluate land use and building on viaduct. The work will be based on literature and interview studies. Sections of

In vivo evaluation of electron mediators for the reduction of methemoglobin encapsulated in liposomes by using electron energies produced by red blood cell glycolysis

Previous studies clarified that the electron enriched NADH and NADPH by RBC glycolysis could be used in an extracellular chemical reaction, where electron energies are extracted by an electron mediator methylene blue (MB). The reduced form of MB permeates the phospholipid bilayer of liposomes and reduce encapsulated ferric methemoglobin (metHb) to ferrous hemoglobin. Moreover, in vitro screening s