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The current research focuses in understanding how inlet pressure, EGR, combustion phasing, engine speed and pilot main ratio are affecting the main parameters of the combustion (e.g. efficiency, NOx, soot, maximum pressure rise rate) in the novel concept of injecting high octane number fuels in partially premixed combustion. The influence of the above mentioned parameters was studied by performing

All stars are formed in some form of cluster or association. These environments can have a much higher number density of stars than the field of the galaxy. Such crowded places are hostile environments: a large fraction of initially single stars will undergo close encounters with other stars or exchange into binaries. We describe how such close encounters and exchange encounters will affect the pr

Flexible goniometers are useful for direct movement measurements. Crosstalk due to rotation between the endblocks is well known. However, even without any rotation, some crosstalk can occur. The objective of this study was to elucidate the effect of, and compensate for, the inherent crosstalk in biaxial goniometers, with specific relevance for applications with one dominating movement direction. S

Alternative oxidase (AOX) functions in stress resistance by preventing accumulation of reactive oxygen species (ROS), but little is known about in vivo partitioning of electron flow between AOX and the cytochrome pathway. We investigated the relationships between AOX expression and in vivo activity in Nicotiana sylvestris and the complex I–deficient CMSII mutant in response to a cell death elicito

The present thesis investigated how listeners use prosody to rapidly predict upcoming lexical and syntactic structures. In the first three studies, it was shown that listeners take advantage of Swedish word-level tones to pre- activate upcoming word endings. Every Swedish word has a tone on the word stem – known as a ‘word accent’ – which is either low or high, and the tone is assigned to the stem

The molecular nature of a severe multisystemic disorder with a recurrent nonimmune hydrops fetalis was identified as deficiency of GDP-Man:GlcNAc 2-PP-dolichol mannosyltransferase, the human orthologue of the yeast ALG1 gene (MIM 605907). The disease belongs to the group of congenital disorders of glycosylation (CDG) and is designated as subtype CDG-Ik. In patient-derived serum, the total amount o

Congenital microcephaly, intractable seizures and severe psychomotor retardation characterize 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, a disorder of L-serine biosynthesis. The enzyme defect results in low concentrations of serine and to a variable degree of glycine in plasma and cerebrospinal fluid. Short-term beneficial effects have been reported of oral treatment with the deficient

Hematopoietic stem cells (HSCs) compose a rare population of undifferentiated cells, residing in the bone marrow of adult individuals, ensuring life-long maintenance and replenishment of the blood system. This fantastic achievement is possible owing to two special characteristics of the HSCs: their ability to make copies of themselves (self-renew), and their capacity to differentiate to all lineag

As automatic sensing and Information and Communication Technology (ICT) get cheaper, building monitoring data is easier to obtain. The abundance of data leads to new opportunities in the context of energy efficiency in buildings. This paper describes ongoing developments and first results of data-driven grey-box modelling for buildings. A Python toolbox is developed based on a Modelica library wit

The laminar burning velocity is a fundamental property of combustiblemixtures important for kinetic model validation as well as for practicalapplications. Many efforts are directed towards its accurate determination.The heat flux method is one of the commonly recognized methodsfor measuring laminar burning velocity, however, the information on theaccuracy of the method is scattered in the literatu

Sepona Freitas and Barbosa, gen. nov. is proposed for the Neotropical satyrine butterfly species Euptychia punctata Weymer, 1911 and its junior subjective synonyms Euptychia griseola Weymer, 1911 and Taygetis indecisa Ribeiro, 1931. The new genus has a distinctive wing pattern and shape of the valvae in the male genitalia, the latter being a unique autapomorphy within the subtribe Euptychiina. Bas

Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell surface. When the dosing of oligomers was stopped the intracellular calcium returned to basal levels o

This thesis employs an international comparative perspective to empirically analyse the Czech energy transition between 1830 and 2010. It addresses the utilization of energy in shaping modern economic growth through structural and technological change and the implications of those changes on specialization and foreign trade. New historical data is collected and utilized to investigate the impact o

Background: Terlipressin has been suggested as the ideal drug to treat anesthesia-induced hypotension in patients under long-term renin-angiotensin system inhibitor treatment for arterial hypertension. The authors compared the effects of terlipressin and norepinephrine on systemic hemodynamic parameters and gastric mucosal perfusion using a laser Doppler flowmetry technique in patients treated wit