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MIRD Pamphlet No. 32 : A MIRD Recovery Coefficient Model for Resolution Characterization and Shape-Specific Partial-Volume Correction

Accurate quantification in emission tomography is essential for internal radiopharmaceutical therapy dosimetry. Mean activity concentration measurements in objects with diameters less than 10 times the full width at half maximum of the imaging system’s spatial resolution are significantly affected (>10%) by the partial-volume effect. This study develops a framework for PET and SPECT spatial resolu

Addition of biological therapies to palliative chemotherapy prolongs survival in patients with peritoneal carcinomatosis of colorectal origin

OBJECTIVES: Combination chemotherapy regimens have shown promising results in patients with metastatic colorectal cancer. However, only very few studies have studied the effect of palliative chemotherapy in peritoneal carcinomatosis (PC) and no data are present incorporating biological therapies in the treatment of PC in colorectal cancer.METHODS: By means of merging with the regional Eindhoven Ca

Multiplex agglutination-PCR (ADAP) autoantibody assays compared to radiobinding autoantibodies in type 1 diabetes and celiac disease

Multiplex Antibody-Detection by Agglutination-PCR (ADAP) assay was compared to singleplex standard radiobinding assays (RBA) to detect autoantibodies against insulin (IAA), GAD65 (GADA), islet antigen-2 (IA-2A), ZnT8 (ZnT8A) and tissue transglutaminase (TGA). Serum samples from 272 (114F/158M), 15-73 years of age healthy controls and 227 (109F/118M) newly diagnosed type 1 diabetes children, 1-11 y

Dose-efficient multimodal microscopy of human tissue at a hard X-ray nanoprobe beamline

X-ray fluorescence microscopy performed at nanofocusing synchrotron beamlines produces quantitative elemental distribution maps at unprecedented resolution (down to a few tens of nanometres), at the expense of relatively long measuring times and high absorbed doses. In this work, a method was implemented in which fast low-dose in-line holography was used to produce quantitative electron density ma

POINT OF VIEW Beware ‘persuasive communication devices’ when writing and reading scientific articles

Authors rely on a range of devices and techniques to attract and maintain the interest of readers, and to convince them of the merits of the author’s point of view. However, when writing a scientific article, authors must use these ‘persuasive communication devices’ carefully. In particular, they must be explicit about the limitations of their work, avoid obfuscation, and resist the temptation to

Brain Fingerprinting Using FMRI Spectral Signatures On High-Resolution Cortical Graphs

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of brain regions. This approach, first, disregards the exquisite spatial detail manifested by fMRI due to working on average regional activities, se

High-resolution spectroscopic techniques for studying rare-earth ions in nanoparticles

Rare-earth doped nanoparticles can exhibit narrow optical and spin linewidths at low temperatures. These outstanding properties for nanomaterials make them attractive for quantum technologies based on optically addressable spins such as quantum memories and computers. Although accurate linewidth measurements have been reported using, for example, spectral hole burning or photon echo techniques, so

The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in the human kidney

Induction of SRY box transcription factor 9 (SOX9) has been shown to occur in response to kidney injury in rodents, where SOX9-positive cells proliferate and regenerate the proximal tubules of injured kidneys. Additionally, SOX9-positive cells demonstrate a capacity to differentiate toward other nephron segments. Here, we characterized the role of SOX9 in normal and injured human kidneys. SOX9 exp

A Screening Tool to Quickly Identify Movement Disorders in Patients with Inborn Errors of Metabolism

BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders.OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movemen

Haraldsson hordur

Microsoft Word - thesis final doc 10 des 98 version 2000.doc Hördur V. Haraldsson Is ecological living in Sweden different from conventional living? i Is ecological living in Sweden different from conventional living? -A case study of the ecological village Toarp and the conventional town Oxie in south Sweden Master’s thesis December 1998 By Hörður V. Haraldsson Supervisors: Janusz Niemczynowicz,

https://www.lumes.lu.se/sites/lumes.lu.se/files/haraldsson_hordur.pdf - 2026-05-24

Luvre-154 2017-fagelaret2016

200 fågelåret 2016 martin green & åke lindström Inom LUVRE-projektet (Lund University Vin- del River Expedition) bedrivs fågelövervakning och forskning runt Ammarnäs, Lycksele lappmark, Västerbottens län, sedan 1963. Fjällfåglarna i Vin- delfjällen med omnejd följs med årliga revirkarte- ringar, linjeinventeringar, ringmärkning och rik- tade studier. Därtill inventeras på ett systematiskt sätt ins

https://www.luvre.lu.se/sites/luvre.lu.se/files/luvre-154_2017-fagelaret2016.pdf - 2026-05-24

Exploring novel genomic biomarkers for response and survival after neoadjuvant chemotherapy and radical cystectomy of muscle-invasive bladder cancer

Background: Neoadjuvant cisplatin-based combination chemotherapy (NAC) is standard perioperative treatment of patients with muscle-invasive urothelial bladder cancer (MIBC); however, about half of the patients experience recurrence of the disease. Biomarkers for response and survival represent an unmet medical need. We used tumor specimens from transurethral resections of the bladder to explore ge

Rapid ecosystem response to abrupt climate changes during the last glacial period in western Europe, 40-16 ka

We present a high-resolution and independently dated multiproxy lake sediment record from the paleolake at Les Echets in southeastern France that displays synchronous changes in independent limnic and terrestrial ecosystem proxies, in concert with millennial-scale climate oscillations during the last glacial period. Distinct lake-level fluctuations, low lake organic productivity, and open, treeles

A review on ergonomics of headgear: Thermal effects

The thermal effects related to wearing headgear are complex and different studies have investigated single parts of this topic. This review aims at summarizing the different findings to give a complete overview on this topic as well as to suggest new perspectives. Headgear increases head insulation and therefore is mainly problematic under warm conditions, which is the focus of this review. Helmet

Towards an efficient atomic frequency comb quantum memory

We present an efficient photon-echo experiment based on atomic frequency combs [Phys. Rev. A 79 (2009) 052329]. Echoes containing an energy of up to 35% of that of the input pulse are observed in a Pr3+ -doped Y2SiO5 crystal. This material allows for the precise spectral holeburning needed to make a sharp and highly absorbing comb structure. We compare our results with a simple theoretical model w

A Pooled Analysis of Thyroid Cancer Incidence Following Radiotherapy for Childhood Cancer

Childhood cancer five-year survival now exceeds 70-80%. Childhood exposure to radiation is a known thyroid carcinogen; however, data are limited for the evaluation of radiation dose-response at high doses, modifiers of the dose-response relationship and joint effects of radiotherapy and chemotherapy. To address these issues, we pooled two cohort and two nested case-control studies of childhood can

Can a "state of the art" chemistry transport model simulate Amazonian tropospheric chemistry?

We present an evaluation of a nested high-resolution Goddard Earth Observing System (GEOS)-Chem chemistry transport model simulation of tropospheric chemistry over tropical South America. The model has been constrained with two isoprene emission inventories: (1) the canopy-scale Model of Emissions of Gases and Aerosols from Nature (MEGAN) and (2) a leaf-scale algorithm coupled to the Lund-Potsdam-

Quantitative Proteomics Profiling of Primary Lung Adenocarcinoma Tumors Reveals Functional Perturbations in Tumor Metabolism

In this study, we have analyzed human primary lung adenocarcinoma tumors using global mass spectrometry to elucidate the biological mechanisms behind relapse post surgery. In total, we identified over 3000 proteins with high confidence. Supervised multivariate analysis was used to select 132 proteins separating the prognostic groups. Based on in-depth bioinformatics analysis, we hypothesized that