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Magnetoliposomes (MLs) were synthesized and tested for longitudinal monitoring of transplanted pancreatic islets using magnetic resonance imaging (MRI) in rat models. The rat insulinoma cell line INS-1E and isolated pancreatic islets from outbred and inbred rats were used to optimize labeling conditions in vitro. Strong MRI contrast was generated by islets exposed to 50 µg Fe/ml for 24 hours witho

Background: Intracerebral transplantation of human induced pluripotent stem cells (iPSCs) can ameliorate behavioral deficits in animal models of stroke. How the ischemic lesion affects the survival of the transplanted cells, their proliferation, migration, differentiation, and function is only partly understood. Methods: Here we have assessed the influence of the stroke-induced injury on grafts of

5-Fluorouracil (5FU) is a fluoropyrimidine used for the treatment of solid tumors. 5FU is a precursor of dTTP and UTP during biogenesis, and it interferes with both DNA and RNA metabolism. The RNA exosome, a multisubunit complex with ribonucleolytic activity, has been identified as one of the targets of 5FU in yeast. Studies in human cells have shown that the catalytic subunit of the nuclear exoso

Expression of minigenes encoding tetra- or pentapeptides MXLX or MXLXV (E peptides), where X is a nonpolar amino acid, renders cells erythromycin resistant whereas expression of minigenes encoding tripeptide MXL does not. By using a 3A' reporter gene system beginning with an E-peptide-encoding sequence, we asked whether the codons UGG and GGG, which are known to promote peptidyl-tRNA drop-off at e

Let C be the unit circle in R2. We can view C as a plane graph whose vertices are all the points on C, and the distance between any two points on C is the length of the smaller arc between them. We consider a graph augmentation problem on C, where we want to place k ≥ 1 shortcuts on C such that the diameter of the resulting graph is minimized. We analyze for each k with 1 ≤ k ≤ 7 what the optimal

Att bli förälder är en stor livsomställning och föräldrars upplevelse av första tiden efter att barnet fötts påverkas bland annat av den information och förberedelse de får under graviditeten. Depression efter förlossningen drabbar cirka 10 % av alla föräldrar, något som även kan påverka anknytningen till barnet och därigenom barnets hälsa och utveckling. Tidigare forskning har visat att nyblivna Parents often feel inadequately prepared for challenges of early parenthood. This thesis aimed to develop an evidence-based programme for antenatal preparation for early parenthood and to test its feasibility. The Medical Research Council’s framework for development and evaluation of complex interventions was used to design the three studies.Interviews were conducted with first-time parents; 18 mo

Hypomyelination is observed in the context of a growing number of genetic disorders that share clinical characteristics. The aim of this study was to determine the possible role of magnetic resonance imaging pattern recognition in distinguishing different hypomyelinating disorders, which would facilitate the diagnostic process. Only patients with hypomyelination of known cause were included in thi

Early aetiological diagnosis is of paramount importance for childhood dystonia because some of the possible underlying conditions are treatable. Numerous genetic and non-genetic causes have been reported, and diagnostic workup is often challenging, time consuming and costly. Recently, a paradigm shift has occurred in molecular genetic diagnostics, with next-generation sequencing techniques now all

Neural stem cell populations generate a wide spectrum of neuronal and glial cell types in a highly ordered fashion. MicroRNAs are essential regulators of this process. T-UCstem1 is a long non-coding RNA containing an ultraconserved element, and in vitro analyses in pluripotent stem cells provided evidence that it regulates the balance between proliferation and differentiation. Here we investigate

A major focus of Alzheimer's disease (AD) research has been finding sensitive outcome measures to disease progression in preclinical AD, as intervention studies begin to target this population. We hypothesize that tailored measures of longitudinal change of the medial temporal lobe (MTL) subregions (the sites of earliest cortical tangle pathology) are more sensitive to disease progression in precl

To capture highly dynamic biological processes at cellular resolution is a recurring challenge in biology. Here we show that combining selective-volume illumination with simultaneous acquisition of orthogonal light fields yields three-dimensional images with high, isotropic spatial resolution and a significant reduction of reconstruction artefacts, thereby overcoming current limitations of light-f

Forskare, från Piaget till Huizinga, MacCannell, Turner, Betcher, Suits, Aarseth, Castronova, Boellstorff, Caillois och Sutton-Smith, för att nämna endast några få, har i decennier och med olika disciplinära angreppssätt försökt förstå sig på lek och spel. “Play” – är ett högst tvetydigt begrepp så brett och metaforiskt att det motstår alla försök att inlemma det under en och samma paraplyteori. P

Popular Abstract in Swedish Fyllotaxi är läran om blad, löv, och andra växtorgans placering. Ordet fyllotaxi har sitt ursprung i de grekiska orden för 'blad' och 'organisation', och mönsterbildning i växter har studerats sedan antiken. Mönster i naturen har alltid intresserat människan och fantasieggande kopplingar till matematiken gör sig ständigt till känna. I många växter bildar växtorgan mönstThe study of phyllotactic patterns have a long history, but the bulk of our detailed understanding of developmental processes in plants comes from research conducted in the last thirty or forty years. New modern techniques have made it possible to study plants in ways that previously was not possible. Using confocal microscopy it is possible to generate three-dimensional stacks of images of a plan

We have studied the nature of the S 2p → 4eg shape resonance in the SF6 molecule by performing two different experiments. Soft X-ray emission spectra measured at the 4eg shape resonance reveal features that do not originate from the S 2p-1 states. One of the features can be assigned to the 6a1g → S 2p transition. The 6a1g orbital, which is empty in the molecular ground state, can be populated eith

Popular Abstract in Swedish Hur är grannsämjan i skånska vattendrag?

Grönling, öring och signalkräfta är tre vanligt förekommande arter i rinnande vatten i Skåne. Öringens biologi och ekologi är väl undersökta och den är dessutom en populär sportfisk. Signalkräftan inplanterades i slutet på 1960-talet för att ersätta den inhemska flodkräftan och är även den ekonomiskt viktig, samt Stream ecosystems are dynamic and they have an inherent environmental variability. Organisms that live in streams are adapted to the continuously changing environment and the presence or absence of species are determined by their environmental requirements, while abundance is most often affected by interactions, such as competition and predation, with other species that are found in the same habit

OBJECTIVE: Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs) identified through targeted complementary approaches affect diabetes incidence in the at-risk population of the Diabetes Prevention Program (DPP) and whether they influence a response to preventive interventions. RESEARCH DESIGN

Anvisningar för sökande till Masterprogrammet i Fri Konst, 120 hp (Master of Fine Arts) Läsår 2021/2022 Sista ansökningsdag 1 april 2021 V 1.2 Viktiga hålltider och information om ansökan till masterprogrammet i fri konst vid Konsthögskolan i Malmö Ansökan i två steg senast 1 april 2021 1. Generell anmälan på Antagning.se Gå in på Universitets- och högskolerådet webbplats www.antagning.se och följ

https://www.khm.lu.se/sites/khm.lu.se/files/2021-02/mastsve2021.pdf - 2026-04-27

inget herrgårdsliv Vilka satsningar lyfter forskningen? All inclusive exkluderar värdlandet 2 LUM nr 4 | 2012 LUM nr 4 | 2012 3 Inför en trollbunden publik spelade International Theatre of Malmö lunchteater på Pufendorfinstitutet. Konstnärlig ledare för ensemblen är Etzel Cardeña, Lunds psykologi­ professor med särskild inriktning mot hypnos och parapsykologi. När Etzel Cardeña läste psykologi på

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-4-2012.pdf - 2026-04-27