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Outcome after percutaneous coronary intervention for different indications : Long-term results from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)

Aims: The aim of this study was to evaluate clinical outcome for different indications for PCI in an unselected, nationwide PCI population at short-and long-term follow-up. Methods and results: We evaluated clinical outcome up to six years after PCI in all patients undergoing a PCI procedure for different indications in Sweden between 2006 and 2010. A total of 70,479 patients were treated for stab

The intersubjective role of I think constructions in conversation : Combining evidence from corpus and experimental techniques

Combining data from spontaneous face-to-face conversations in the London-Lund Corpus (LLC) of spoken British English and a laboratory experiment, this paper analyses the dynamic nature of I think constructions in dialogue. We make use of the functional category of ENGAGEMENT in APPRAISAL theory as an analytical tool (Martin & White, 2005). More precisely, we examine whether I think constructio

Long term azathioprine maintenance therapy in ANCA-associated vasculitis : combined results of long-term follow-up data

Methods: Three hundred and eighty newly diagnosed ANCA-associated vasculitis patients from six European multicentre studies treated with AZA maintenance were included; 58% were male, median age at diagnosis 59.4 years (interquartile range: 48.3-68.2 years); granulomatosis with polyangiitis, n = 236; microscopic polyangiitis, n = 132; or renal limited vasculitis, n = 12. Patients were grouped accor

Differential regulation of α and β chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S

Regulation of C4b-binding protein (C4BP) isoforms during acute phase and its relationship to the plasma concentration of free protein S was elucidated. An assay for β chain containing C4BP (C4BPβ+) was developed and the concentrations of total C4BP, C4BPβ+, total, free, and bound protein S were measured in patients with acute-phase response. Even though total C4BP was increased to 162% (mean value

Challenges and opportunities in land surface modelling of savanna ecosystems

The savanna complex is a highly diverse global biome that occurs within the seasonally dry tropical to sub-tropical equatorial latitudes and are structurally and functionally distinct from grasslands and forests. Savannas are open-canopy environments that encompass a broad demographic continuum, often characterised by a changing dominance between C3-tree and C4-grass vegetation, where frequent env

Role of osteopontin and its regulation in pancreatic islet

Osteopontin (OPN) is involved in various physiological processes and also implicated in multiple pathological states. It has been suggested that OPN may have a role in type 2 diabetes (T2D) by protecting pancreatic islets and interaction with incretins. However, the regulation and function of OPN in islets, especially in humans, remains largely unexplored. In this study, we performed our investiga

Analysis and exploitation of resource efficiency potentials in industrial small and medium-sized enterprises – Experiences with the EDIT Value Tool in Central Europe

Material and energy costs represent about 50% of the operating costs incurred by European small and medium-sized enterprises (SMEs). Although the potential for resource efficiency improvements is high, the necessary awareness and human resource capacities to explore this potential are limited. Existing tools for exploration of resource efficiency improvement potentials have several shortcomings: t

5G : A tutorial overview of standards, trials, challenges, deployment, and practice

There is considerable pressure to define the key requirements of 5G, develop 5G standards, and perform technology trials as quickly as possible. Normally, these activities are best done in series but there is a desire to complete these tasks in parallel so that commercial deployments of 5G can begin by 2020. 5G will not be an incremental improvement over its predecessors; it aims to be a revolutio

Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer

In a previous study, we detected a significant association between phosphoserine aminotransferase 1 (PSAT1) hyper-methylation and mRNA levels to outcome to tamoxifen treatment in recurrent disease. We here aimed to study the association of PSAT1 protein levels to outcome upon tamoxifen treatment and to obtain more insight in its role in tamoxifen resistance. A cohort of ER positive, hormonal thera

VENTURI - immersiVe ENhancemenT of User-woRld Interactions

The Augmented Reality (AR) concept has excited visionaries and researchers for decades, and finally its enabling technologies are beginning to materialize on consumer-grade mobile devices. The availability of powerful mobile computing platforms combined with fast mobile Internet access, opens the door to ‘solid’ visual/auditory augmentation of the world with geo-spatial knowledge, distilled from

First Identification of Excited States in 59Zn

Excited states in 59Zn were observed for the first time following the fusion-evaporation reaction 24Mg + 40Ca at a beam energy of 60 MeV. The GASP array in conjunction with the ISIS Silicon ball and the NeutronRing allowed for the detection of n-rays in coincidence with evaporated light particles. The mirror symmetry of 59Zn and 59Cu is discussed.

Multiband amplitude modulated sinusoidal audio modeling

In this paper, we investigate the importance of taking frequency-dependent temporal phenomena into account in audio coding. We do this in the context of sinusoidal modeling of audio signals by applying amplitude modulation to the sinusoidal components. Traditionally, audio coders use a fixed time-segmentation for all frequencies despite that it is well-known that the time-frequency resolution of t

Sigrid Combüchen's Parsifal – time and memory in a dissoluting Europe. A Narrative analysis in Comparison with Aethiopica by the ancient novelist Heliodorus (300 AD).

A comparison between the narrative technique of the ancient Greek novel, 'The Aethiopica' by Heliodorus, and Sigrid Combüchen´s modern tale 'Parsifal'.

Sigrid Combüchen is a Swedish writer, born in Germany 1943, a european 'war child'. Her tale Parsifal (1998) gives perspective of the perils in European history. She uses a historical, mythical and contemporary narrative in a genuinely

Genetic analyses of multiple myeloma and related plasma cell dyscrasias

Popular Abstract in Swedish Elakartade (maligna) blodsjukdomar uppstår i den blodbildande benmärgen, vilken är innesluten i hålrummen i de skelettdelar som kan sägas täckas av en badmössa och en gammaldags baddräkt. En av de celltyper som bildas i benmärgen är plasmacellen, en vit blodkropp som utgör mindre än 2% av benmärgscellerna och som tillverkar specifika antikroppar vid infektioner. Vid monAcquired genetic changes have proved to be of diagnostic and prognostic importance in different hematologic malignancies as well as in some solid tumor types. However, although multiple myeloma (MM), an incurable disease, and its proceeding stage monoclonal gammopathy of undetermined significance (MGUS) are quite common, little is known about the karyotypic features of these plasma cell dyscrasias

High-spin structure in Er-157 up to and above band termination

The high-spin structure of Er-157 has been greatly expanded using the Gammasphere spectrometer to investigate the Cd-114(Ca-48,5n) reaction at 215 MeV. Many new transitions have been placed in a greatly augmented level scheme up to spin 40h with many collective rotational sequences established. With increasing angular momentum, this nucleus undergoes a Coriolis-induced shape transition from a defo