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Inner ear is a target for insulin signaling and insulin resistance : evidence from mice and auditory HEI-OC1 cells

OBJECTIVE: The mechanisms underlying the association between diabetes and inner ear dysfunction are not known yet. The aim of the present study is to evaluate the impact of obesity/insulin resistance on inner ear fluid homeostasis in vivo, and to investigate whether the organ of Corti could be a target tissue for insulin signaling using auditory House Ear Institute-Organ of Corti 1 (HEI-OC1) cells

Influence of boundary layer dynamics and isoprene chemistry on the organic aerosol budget in a tropical forest

We study the organic aerosol (OA) budget in a tropical forest by analyzing a case that is representative for the OP3 campaign at Borneo. A model is designed that combines the essential dynamical and chemical processes that drive the diurnal evolution of reactants in the atmospheric boundary layer (BL). In this way, the model simultaneously represents the effects and interactions of various dynamic

Pathogen suppression by microbial volatile organic compounds in soils

There is increasing evidence that microbial volatile organic compounds (mVOCs) play an important role in interactions between microbes in soils. In this minireview, we zoom in on the possible role of mVOCs in the suppression of plant-pathogenic soil fungi. In particular, we have screened the literature to see what the actual evidence is that mVOCs in soil atmospheres can contribute to pathogen sup

Gender

My chapter gives an overview of gender and religion in Europe in the “long” 19th century based on developments in historical research since the 1980s. The focus is on Catholicism and Protestantism with some reflexions also on Judaism and Orthodox Christianity.

Rare inborn errors of metabolism with movement disorders : a case study to evaluate the impact upon quality of life and adaptive functioning

BACKGROUND: Inborn errors of metabolism (IEM) form an important cause of movement disorders in children. The impact of metabolic diseases and concordant movement disorders upon children's health-related quality of life (HRQOL) and its physical and psychosocial domains of functioning has never been investigated. We therefore conducted a case study on the HRQOL and development of adaptive functionin

Domain-Informed Spline Interpolation

Standard interpolation techniques are implicitly based on the assumption that the signal lies on a single homogeneous domain. In contrast, many naturally occurring signals lie on an inhomogeneous domain, such as brain activity associated to different brain tissue. We propose an interpolation method that instead exploits prior information about domain inhomogeneity, characterized by different, pote

Permanent pacemaker implantation early and late after heart transplantation : clinical indication, risk factors and prognostic implications

BACKGROUND: Permanent pacemaker implantation (PPM) early after cardiac transplantation has been shown not to predict a worse outcome. However, the requirement for pacing late after transplantation and its prognostic implications are not fully known. We describe the clinical indications, risk factors and long-term outcome in patients who required pacing early and late after transplantation.METHODS:

Evaluation of simulation-assisted value stream mapping for software product development : Two industrial cases

Context: Value stream mapping (VSM) as a tool for lean development has led to significant improvements in different industries. In a few studies, it has been successfully applied in a software engineering context. However, some shortcomings have been observed in particular failing to capture the dynamic nature of the software process to evaluate improvements i.e. such improvements and target value

Utvärdering av dubbdäcksförbudets effekt på luftkvaliteten på Friggagatan

I syfte att utvärdera effekten av dubbdäcksförbudet på Friggagatan med avseende på luftkvaliteten har Miljöförvaltningen i Göteborg på uppdrag av trafikkontoret i Göteborg utfört luftkvalitetsmätningar på Friggagatan mellan 2013-01-01 och 2013-09-30. Dessutom utförde Miljöförvaltningen mätningar av dubbdäcksanvändningen på Friggagatan, vid Drottningtorget och i Haga. Vidare användes även mätdata f

Brominated Flame Retardants and Organophosphate Esters in Preschool Dust and Children's Hand Wipes

Children spend a considerable part of their day in preschool, where they may be exposed to hazardous chemicals in indoor dust. In this study, brominated flame retardants (BFRs) and organophosphate esters (OPEs) were analyzed in preschool dust (n = 100) and children's hand wipe samples (n = 100), and diphenyl phosphate (DPHP) was analyzed in urine (n = 113). Here we assessed children's exposure via

Som vem som helst : Kön, funktionalitet och idrottande kroppar

Popular Abstract in Swedish Avhandlingens huvudsakliga syfte är att utforska unga kvinnors levda erfarenheter av en kropp som å ena sidan betraktas som avvikande – den fysiskt funktionsnedsatta eller rörelsehindrade kroppen – å andra sidan betraktas som presterande – den idrottande kroppen. De frågor som ställs i avhandlingen är hur de unga kvinnorna förhandlar de båda subjektspositioner som uppstThe main aim of this thesis is to explore young women’s lived experience of the body, which, on one hand, is viewed as deviant – the disabled body – and, on the other hand, is viewed as accomplished – the sporting body. The questions posed in the thesis are the following: how do the young women handle the two subject positions that emerge as a result of the perception of them as respectively devia

Marine silicon cycle through the Cenozoic

Omsättningen av kisel (Si) är en av de viktiga biogeokemiska processerna på jorden. Den lösta formen av Si (DSi) är ett nödvändigt näringsämne för såväl markens som havens ekosystem. Löst kisel kommer från den långsamma kemiska vittringen av kiselmineral. Denna process förbrukar koldioxid och bidrar därför till att reglera jordens klimat genom årmiljonerna. Kisel transporteras huvudsakligen via odSilicon (Si) cycle is one of Earth's major biogeochemical cycles. Furthermore, the dissolved form of Si (DSi) is an essential nutrient for both terrestrial and marine ecosystems. DSi ultimately derives from the slow process of chemical weathering of silicate minerals, a mechanism that consumes carbon dioxide, and therefore participates in regulating Earth's climate over geologic timescales. Si is

As if Peoples Mattered: Critical Appraisal of "Peoples" and "Minorities" from the International Human Rights Perspective and Beyond

The subject matter of the thesis is the comprehensive - legal and multidisciplinary - analysis of the terms 'peoples' and 'minorities' in international law. The argument of the author proceeds in four parts: the Problematique which deals with the 'minority challenge' and the international normative response to that challenge; the Critique, criticizing the basic underlying assumptions of the discou

The Mechanism of Market Driving with a Corporate Brand - The Case of a Global Retailer

The purpose of this thesis has been to analyse the mechanism of the market driving approach carried out by a global organisation with a corporate brand. Market driving is a new organisational approach to strategy that lacks a solid theoretical framework, but constitutes a reality of global firms such as IKEA, The Body Shop, Benetton, Dell, Hennes and Mauritz, Starbucks. In the literature, the mark

How to gain synchronization between business processes and enterprise resource planning systems : a SOA bases perspective on ERP implementation

A major question in organizations is how to support Business Processes (BPs) by an Enterprise Resource Planning (ERP) system. In this paper we present thoughts on designing implementation processes of ERPs using a Service Oriented Architecture (SOA) based perspective: The starting point is based on the idea of decomposing an ERP from a SOA based perspective and thereby supporting automation of imp