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Atrial Fibrillation in Long QT Syndrome by Genotype

BACKGROUND: Long QT syndrome (LQTS) is caused by the abnormal function of ion channels, which may also affect atrial electrophysiology and be associated with the risk of atrial fibrillation (AF). However, large-scale studies of AF risk among patients with LQTS and its relation to LQTS manifestations are lacking. We aimed to assess the risk of AF and its relationship to the LQTS genotype and the lo

Animals and the Politics of Suffering : Essays on Law, Care and Interspecies Relations

Syftet med denna sammanläggningsavhandling är att belysa de etiska, juridiska och politiska konsekvenserna av olika försök att hantera lidande hos djur orsakat av industriell djurproduktion. På basis av kvalitativa studier utförda i Danmark undersöker avhandlingen hur skötseln av lantbruksdjur förhandlas inom olika sociala domäner. För detta ändamål använder avhandlingen rättssociologiska och tvärThis compilation thesis aims to develop an understanding of the ethical, legal and political implications associated with different strategies to address the suffering of animals caused by industrialised agriculture. Based on qualitative analysis conducted in Denmark, the research explores how ethical commitment to the situation of farmed animals is negotiated across different domains. The thesis

HLA Class I Genotype Is Associated with Relapse Risk after Allogeneic Stem Cell Transplantation for NPM1-Mutated Acute Myeloid Leukemia

Mutation-bearing peptide ligands from mutated nucleophosmin-1 (NPM1) protein have been empirically found to be presented by HLA class I in acute myeloid leukemia (AML). We hypothesized that HLA genotype may impact allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes in NPM1-mutated AML owing to differences in antigen presentation. We evaluated the effect of the variable of predic

Elevrekrytering? - Tre kontrabaslärares tankar kring barns och ungdomars första tid på musik och kulturskolor.

Student recruitment? - Three teachers? thoughts concerning children's first experiences in municipal arts and music schools. The aim of this thesis is to explore three teacher' experiences of recruitment of students to arts and music schools. The thesis includes thoughts about how teachers can inspire students and why the orchestral string bass is an infrequent choice of instrument to stud

Musik som socialt redskap - Musikens betydelse i arbetet med socialt utsatta barn, en studie ur ett rytmikmetodiskt perspektiv

The main purpose of this study is to inquire whether music can function as a supportive and compensating tool for children from various kinds of social exposure. Eurhythmics is the musical method focused on, since it consciously works out of a socializing perspective. The study involves a scheme with poor children in Argentin (autumn 2005) and is based upon two interviews with women working profes

Reliability of virtual non-contrast computed tomography angiography: comparing it with the real deal

Background:Computed tomographic angiography (CTA) may require a non-contrast enhanced dataset for the diagnostic workup. By using dual-energy acquisition, it is possible to obtain a virtual non-contrast-enhanced (VNC) dataset, thereby possibly eliminating the non-contrast acquisition and reducing the radiation dose.Purpose:To compare image quality of VNC images reconstructed from arterial phase du

Scaling up nature-based solutions for climate-change adaptation : Potential and benefits in three European cities

Many exemplary projects have demonstrated that Nature-based Solutions (NBS) can contribute to climate change adaptation, but now the challenge is to scale up their use. Setting realistic policy goals requires knowing the amount of different NBS types that can fit in the urban space and the benefits that can be expected. This research aims to assess the potential for a full-scale implementation of

A Combination of Metaheuristic Optimization Algorithms and Machine Learning Methods Improves the Prediction of Groundwater Level

Groundwater is a crucial source of water supply in drought conditions, and an auxiliary water source in wet seasons. Due to its increasing importance in view of climate change, predicting groundwater level (GWL) needs to be improved to enhance management. We used adaptive neuro-fuzzy inference systems (ANFIS) to predict the GWL of the Urmia aquifer in northwestern Iran under various input scenario

Resource Management in Distributed Camera Systems

The aim of this work is to investigate different methods to solve the problem of allocating the correct amount of resources (network bandwidth and storage space) to video camera systems. Here we explore the intersection between two research areas: automatic control and game theory. Camera systems are a good example of the emergence of the Internet of Things (IoT) and its impact on our daily lives

The political economy of degrowth

What is degrowth and what are its implications for political economy? Divided in three parts, this dissertation explores the why, what, and how of degrowth.The first part (Of growth and limits) studies the nature, causes, and consequences of economic growth. Chapter 1: Understanding economic growth answers a series of questions about the nature of economic growth: What is it exactly that grows? By

Närståendestöd och efterlevandestöd – under och efter vårdtid inom specialiserad Palliativ vård och ASIH i Skåne

Bakgrund: En av hörnstenarna i palliativ vård handlar om att ge stöd till alla närstående. Enligt lagstiftning har sjukvården även en skyldighet att speciellt beakta barns behov av information, råd och stöd om barnets föräldrar eller någon annan vuxen som barnet varaktigt bor tillsammans med har en livshotande sjukdom eller avlidit.Syfte: Alla närstående inom Palliativ vård och ASIH i Skåne ska er

On the estimation of ligand binding affinities

Popular Abstract in Swedish De allra flesta människor har vid något tillfälle tagit ett läkemedel. Till exempel vaccineras nu för tiden alla svenska barn mot bland annat stelkramp. Vad nog de allra flesta däremot inte har gjort är att fundera på vad ett läkemedel är. Kanske sträcker man sig till att ha kollat upp ett läkemedel i FASS, och kanske får man då syn på en figur som består av streck och A method to accurately estimate the binding affinity of a small molecule to a receptor would be indispensable in numerous fields. For instance, most drugs exert their action by binding to a macromolecule target. Thus, a lot of time and resources could be saved in drug design by predicting affinities by computer programs. In a series of 15 papers, we have tested, compared, and improved the most p

Evaluating temporal consistency of long-term global NDVI datasets for trend analysis

As a way to understand vegetation changes, trend analysis on NDVI (normalized difference vegetation index) time series data have been widely performed at regional to global scales. However, most long-term NDVI datasets are based upon multiple sensor systems and unsuccessful corrections related to sensor shifts potentially introduce substantial uncertainties and artifacts in the analysis of trends.

Concentration Camp Rituals: An Extreme Case of Insecurity

Reason(s) for writing and research problem(s): This article analyzes the experiences retold by former concentration camp detainees who were placed in concentration camps like civilians at the beginning of the Bosnian war in the 1990s. Aims of the paper (scientific and/or social): The article aims to describe the recounted social interaction rituals after time spent in a concentration camp as well

In search of “Muda” through the TKJ diagram

Purpose: Muda is a Japanese term literally meaning futility, uselessness, idleness, superfluity, waste, wastage or wastefulness. The term was introduced by the Japanese engineer Taiichi Ohno of Toyota Motor Corporation in the 1960s. Therefore, reducing and minimizing Muda is an effective way to increase the operational efficiency and productivity of an organization’s processes. In turn, the techni

Forecasting global atmospheric CO2

A new global atmospheric carbon dioxide (CO2) real-time forecast is now available as part of the pre- operational Monitoring of Atmospheric Composition and Climate – Interim Implementation (MACC-II) service us- ing the infrastructure of the European Centre for Medium- Range Weather Forecasts (ECMWF) Integrated Forecast- ing System (IFS). One of the strengths of the CO2 fore- casting system is that

Positive Response to Cardiac Resynchronization Therapy : The Role of NT-proBNP

Abstract Background: Cardiac resynchronization therapy (CRT) is effective, but only 60-70% of patients benefit from the therapy. Despite numerous implantations, identification of predictive factors for response is still a challenge. We sought to assess the correlation of echocardiographic and clinical response to baseline demographics in relation to change in NT-proBNP levels at 6 months. Methods:

Endometrial cancer off-line staging using two-dimensional transvaginal ultrasound and three-dimensional volume contrast imaging : Intermethod agreement, interrater reliability and diagnostic accuracy

Objectives: The aim is to estimate agreement between two-dimensional transvaginal ultrasound (2D-TVS) and three-dimensional volume contrast imaging (3D-VCI) in diagnosing deep myometrial invasion (MI) and cervical stromal involvement (CSI) of endometrial cancer and to compare the two methods regarding inter-rater reliability and diagnostic accuracy. Methods: Fifteen ultrasound experts assessed off