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Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft-derived cells Storm et al., Sci. Adv. 10, eadn3057 (2024) 18 October 2024 S c i e n c e A d v A n c e S | R e S e A R c h A R t i c l e 1 of 14 N E U R O S C I E N C E Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft- derived c
Studentbarometern 2012 Konstnärliga Fakulteten Utvärdering L U N D S U N I V E R S I T E T 2 Utvärdering Lunds universitet Box 117 221 00 Lund Tel. vx: 046-222 00 00 Tel: 046-222 94 53 Fax: 046-222 40 07 ISBN 978-91-980094-3-9 (Serien Utvärdering Rapporter är en fortsättning av serien Utvärderingsenheten Rapporter, ISSN 1401-775X) 3 Sammanfattning 5 1. Inledning 9 Enkätundersökningen 10 Urval och
https://www.thm.lu.se/sites/thm.lu.se/files/e03.pdf - 2026-05-20
Popular Abstract in Swedish Utgångspunkten för den här avhandlingen har varit det stora antalet bilder som motsäger den vanliga trenden i konst att avbilda flickor som oskyldiga, romantiska och sexualiserade. Målet med avhandlingen är att för första gången presentera forskning om den svenska konstnären Lena Cronqvists (född 1938) flickbilder och att skapa kunskap om bilder av flickor i konst i allThe starting point for this PhD, is the large number of girls that opposed the common trend in which girls are represented as innocent, romantic and sexual. The aim of this study has been to provide the first piece of research ever on this body of work by the Swedish artist Lena Cronqvist (b. 1938) and to cast new light on representations of girls in art in general. Cronqvist is one of Sweden's ma
A subset of genetic variants found through screening of patients with hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome impact RNA splicing. Through target enrichment of the transcriptome, it is possible to perform deep-sequencing and to identify the different and even rare mRNA isoforms. A targeted RNA-seq approach was used to analyse the naturally-occurring splicing events
The plant polysaccharide degradative potential of Aspergillus nidulans was analysed in detail and compared to that of Aspergillus niger and Aspergillus oryzae using a combination of bioinformatics, physiology and transcriptomics. Manual verification indicated that 28.4% of the A. nidulans ORFs analysed in this study do not contain a secretion signal, of which 40% may be secreted through a non-clas
Background: There is much interest in how the Amazon rainforest may respond to future rainfall reduction. However, there are relatively few ecosystem-scale studies to inform this debate. Aims: We described the carbon cycle in a 1 ha rainforest plot subjected to 8-10 consecutive years of ca. 50% through-fall reduction (TFR) and compare these results with those from a nearby, unmodified control plot
Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. AMD is a multifactorial disorder but complement-mediated inflammation at the level of the retina plays a pivotal role. Oral zinc supplementation can reduce the progression of AMD but the precise mechanism of this protective effect is as yet unclear. We investigated whether zinc supplementation directly a
Popular Abstract in Swedish Sjukdomsuppfattningar. Värderingar och attityder hos patienter och medicine studerande. Utvecklingen av den biomedicinska kunskapen och de demografiska förändringarna under 1900-talet har inneburit en ökning av såväl behov av som efterfrågan på hälso- och sjukvård. Illabefinnande utan påvisbara sjukdomstecken och rädsla för sjukdom ligger ofta bakom vårdsökande. OfficieDuring the 20th century, the development of biomedical knowledge and the demographical changes have increased the needs and demands for health care in industrialised countries. Illness without evidence of disease and fear of disease are often the reasons for seeking medical care. Primary care is the official foundation of the Swedish health care system but priorities are vague and frequently chang
I varje samhälle har konsumenter en avgörande roll för att klimatanpassade varor och tjänster köps, används och till sist källsorteras. En alldeles övervägande andel svenskar har under flera decennier visat sig vara i hög grad miljömedvetna. Klimatförändringar såsom global uppvärmning och ett växande ozonhål har varit bland de aspekter på klimatförändringar man oroat sig mest för. Kunskap om miljö
OBJECTIVE: To develop a prognostic model to predict disease outcomes in individual patients with Parkinson disease (PD) and perform an external validation study in an independent cohort.METHODS: Model development was done in the Comorbidity and Aging in Rehabilitation Patients: The Influence on Activities (CARPA) cohort (Netherlands). External validation was performed using the Cambridgeshire Park
Objectives: This study developed a neural network to perform automated pressure waveform analysis and allow real-time accurate identification of damping. Background: Damping of aortic pressure during coronary angiography must be identified to avoid serious complications and make accurate coronary physiology measurements. There are currently no automated methods to do this, and so identification of
The glutamatergic neurotransmission system and the N-methyl-D-aspartate receptor (NMDAR) have been implicated in smoking and alcohol consumption behavior. Preclinical studies have demonstrated that nicotine and ethanol influence NMDAR functionality, which may have a role in tendencies to consume these substances. Nonetheless, little is known about concentrations of NMDAR coagonists in the cerebros
Aim: Anthropogenic-driven biodiversity loss can impact ecosystem stability. However, most studies have only evaluated the diversity–stability relationship at the local scale and we do not fully understand which factors stabilize animal populations and communities across scales. Here, we investigate the role of species dispersal ability, climate, spatial distance and different facets of biodiversit
Distinguishing between vagrancy and regular migration has proved to be challenging as vagrants may, in theory, act as pioneers in the establishment of new migration routes. Because migratory songbirds tend to follow the same orientation and migration route throughout their lives, age assessment can help to distinguish individuals which have already used a route (i.e. adults) from those using it fo
Introduction: The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery (CRS) improves recurrence-free (RFS) and overall survival (OS) in patients with FIGO stage III ovarian cancer. We evaluated the effect of HIPEC on patient's health-related quality of life (HRQoL) in the OVHIPEC trial. Materials and methods: OVHIPEC was a multicentre, open-label, random
Wastewater generated in tanneries have essential elements for microalgae growth, but it has also some toxic compounds that may hinder or restrain the growth of microalgae in this environment. This work tested microalgae consortium growth originating from a deactivated effluent treatment decanter of a complete tannery (beamhouse to finished leather) for the treatment of wastewater of a tannery proc
Objectives: To evaluate whether the Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis need to be better defined and, if deemed necessary, to reach consensus on the updated definitions. Methods: A modified Delphi procedure was performed among European gynecologists with expertise in ultrasound diagnosis of adenomyosis. To identify MUSA features that might need revision, 15
Som en följd av den ökade globala rörligheten har internationella utsändningar kommit att bli allt vanligare. Dessa utsändningar kräver emellertid en effektiv planering och administration, inte minst vad gäller hanteringen av skatter. Inom internationella företag tillämpas ofta en särskild skattekompensationspolicy för att garantera att den anställde vid en utsändning inte erhåller en lägre disponAs a consequence of the global mobility, the number of international assignments has increased over the past years. International assignment programs require an effective planning and administration, especially regarding the management of taxes. Within global companies, a special tax reimbursement policy is often implemented, designed to reimburse an employee for the additional tax cost of a forei
