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BACKGROUND: TKA generally has excellent long-term survivorship. When a new knee system supersedes a previous model, increased survivorship, improved functional performance, or both may be expected, because key areas of design modification are often targeted to address wear, stability, and the patellofemoral articulation. However, not all design changes are beneficial, and to our knowledge, knee ar

Plasmodium berghei is the causative agent of rodent malaria and is widely used as a model system to study the liver stage of Plasmodium parasites. The entry of P. berghei sporozoites into hepatocytes has extensively been studied, but little is known about parasite-host interaction during later developmental stages of the intracellular parasite. Growth of the parasite far beyond the normal size of

The present thesis investigated how listeners use prosody to rapidly predict upcoming lexical and syntactic structures. In the first three studies, it was shown that listeners take advantage of Swedish word-level tones to pre- activate upcoming word endings. Every Swedish word has a tone on the word stem – known as a ‘word accent’ – which is either low or high, and the tone is assigned to the stem

Hematopoietic stem cells (HSCs) compose a rare population of undifferentiated cells, residing in the bone marrow of adult individuals, ensuring life-long maintenance and replenishment of the blood system. This fantastic achievement is possible owing to two special characteristics of the HSCs: their ability to make copies of themselves (self-renew), and their capacity to differentiate to all lineag

Sekundär användning av e-hälsodata är ett viktigt steg i att direkt och indirekt stärka vården, både inom Sverige och EU. Inom kort förväntas den uppmärksammade EU-förordningen om ett European Health Data Space (EHDS) antas. Genom förordningen kommer ett gemensamt hälsodataområde skapas vilket bland annat möjliggör sekundär användning av uppemot 450 miljoner EU-medborgares e-hälsodata för exempelvSecondary use of e-health data is an important step in directly and indirectly strengthening healthcare, both in Sweden and the EU. The anticipated EU regulation on a European Health Data Space (EHDS) will create a common health data space, allowing for the secondary use of the e-health data of up to 450 million EU citizens for research, innovation and decision-making. This has the potential to re

The hitchhiker’s guide to satellite dependencies For the last half century, humanity has gained access to better weather reports, live coverage of the Olympics, and a handheld map of the globe, all thanks to satellites in space. But what happens if these satellites fail? That question has been asked, but never answered in full. This thesis has aimed to assists researchers in answering that questiVital societal functions and critical infrastructure rely to an increasing extent on services from space, such as navigation and positioning systems, timekeeping, and communications. However, understanding of space service dependencies is low among practitioners and society at large, with research on societal space dependency being limited as well. In order to avoid cascading effects from disrupti

Under vårterminen 2021 genomfördes en avhandling på Volvo GTO. Volvo Lastvagnar är en av de största aktörerna inom fordonsindustrin och levererar lastbilar över hela världen. Företaget erbjuder lastbilar som kan anpassas och modiferas efter kundens önskemål. Att erbjuda lastbilar med hög anpassnings- och förändringsgrad innebär en hel del påfrestningar på systemet vilket kräver att CAD-ritningar,During the spring term of 2021 a thesis was carried out at Volvo Trucks GTO. Volvo Trucks is one of the largest and most successful actors in the automotive industry and delivers trucks all over the world. The company offers trucks that can be customized and adapted according to the customer wishes. Offering highly customizable trucks puts a lot of stresses on the system which requires that CAD-

Global gene expression of reprogrammed dendritic cells Cell reprogramming refers to the emergent ability to transform one cell type into another functional cell type. Gene expression gives us insight into the function of a cell, what protein it is producing and what functional pathways it is maintaining. In this project, I analyzed the expression of all genes of dendritic cells (DCs) reprogrammed

Polar nights, extreme cold, and snow are part of the identity of Arctic cities; these elements together set a particular demand for urban designers to find solutions to make the city more livable and attractive during the long dark days in the winter and still thrive on being enjoyable during the long bright days in the short summers. However, Arctic cities are threatened continuously by shrinking

This thesis focuses on flexible work, known as telework, that is done through the use of information communication technology (ICT) devices in the entertainment, new media and arts sector. Fieldwork was conducted with independent professionals who work either as a producer / director, editor or motion graphic artist for the entertainment, new media and arts sector in the Los Angeles area. When wo

Dizziness and vertigo affect up to 20% of adults annually. Cervicogenic dizziness (CGD), a debated clinical entity, is characterized by dizziness associated with cervical pain or dysfunction, stemming from altered proprioceptive input from the cervical spine. Despite its recognition in clinical practice, CGD remains controversial due to its reliance on exclusionary diagnosis and the absence of spe

Problemformulering: Hur ser IGS strategiska process ut och vilken strategisk position har de idag? Hur påverkas företaget av en föränderlig omvärld? Syfte: Utredningens syfte är att studera och analysera IGS strategiska process samt undersöka hur applicerbara de tre strategiska synsätten är på fallföretaget ifråga. Vi har även för avsikt att se hur stor effekt den föränderliga omvärlden har på för

After a brief outlook on the field of concatenative synthesis of singing, with emphasis on the differences in comparison to synthesis of speech, the present paper gives an overview of a simple system for singing synthesis in Swedish based on concatenation of diphones. The system, called Burcas, accepts as input a text file for lyrics, from which it extracts a target phoneme sequence using basic le

Finns det någon poäng med att övertyga gästerna om varumärkets storhet om inte de anställda är med på tåget? Det har påpekats att utan motiverade och nöjda anställda riskerar varumärkets och ledningens löften till gästerna att bli tomma, då det är personalen som ska leverera den utlovade servicen. Vi anser det intressant att undersöka hur företag inom hotellbranschen arbetar med att motivera sin p

Catalonia is a nation with it's own language, its own culture, own policy and own history it is said. A non-independent nation that is living it's ordinary life flagging its banal symbols as if it al ready was an independent state. Some catalanistas assert that this kind of weirdness could be the death row for Catalonia and its future as in independent nation of its own. They state that it

In 1994, Rwanda was a country ravaged by ethnic violence of an incomprehensible scale as 800,000 people were killed within 100 days. Whilst the abhorrent events of Rwanda’s genocide lack justification, the genocide marked a turning point for women’s position in this traditionally patriarchal society. In this post-conflict context, this study investigates adults’ perceptions of the gendered divisio