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Aims: The Atrophodermas include a large group of disorders appearing as localized or widespread depressed skin areas and characterized by underlying dermal atrophy. The present study aims to report a peculiar form of previously unreported focal dermal atrophy. Methods: We studied over a period of 5 years a boy who manifested, since birth, multiple hypopigmented cutaneous atrophic lesions of the at
This note provides an interim summary of the current recommendations of thePDF4LHC working group for the use of parton distribution functions (PDFs)and of PDF uncertainties at the LHC, for cross section and cross section uncer-tainty calculations. It also contains a succinct user guideto the computation ofPDFs, uncertainties and correlations using available PDF sets.A companion note (the PDF4LHC W
3-Phosphoglycerate dehydrogenase (3-PGDH) deficiency is considered to be a rare cause of congenital microcephaly, infantile onset of intractable seizures and severe psychomotor retardation. Here, we report for the first time a very mild form of genetically confirmed 3-PGDH deficiency in two siblings with juvenile onset of absence seizures and mild developmental delay. Amino acid analysis showed se
BACKGROUND: TKA generally has excellent long-term survivorship. When a new knee system supersedes a previous model, increased survivorship, improved functional performance, or both may be expected, because key areas of design modification are often targeted to address wear, stability, and the patellofemoral articulation. However, not all design changes are beneficial, and to our knowledge, knee ar
Grasslands are a prerequisite for rearing livestock, and livestock is the mainstay of people’s existence in drylands. As one Kenyan woman put it, “without grass there is no livestock, without livestock there is no life.” Based in the lowlands of Baringo County in Kenya’s Rift Valley, RAE (Rehabilitating Arid Environments) Ltd. has worked for 38 years to develop a successful socio-ecological model
This study aims at assess the importance of a conceptual representation of hydrological processes when modelling atmospheric circulation. It compares results from a regional atmospheric model that interprets land surface hydrological processes based on parameterizations with results from a two-way coupled atmosphere-hydrological model that has a process-based approach to the land surface hydrologi
Purpose: This paper has chosen a participatory action design (PAD) to approach the construction of KPIs in a novel way. A PAD will assist the researcher to encourage involvement, engagement of multiple stakeholders in the KPIs construction process. Design/methodology/approach: A workshop series based on participatory action design was developed together with the researcher and stakeholders at the
Following intense research efforts, modulation of the immune system has finally proved to be a viable approach for treating malignant disease. Recently, chimeric antigen receptor redirected T cells have achieved promising outcomes in patients with B-cell malignancies and they are currently also being investigated in other haematological malignancies, solid tumours and viral infections. Compared wi
The current research focuses in understanding how inlet pressure, EGR, combustion phasing, engine speed and pilot main ratio are affecting the main parameters of the combustion (e.g. efficiency, NOx, soot, maximum pressure rise rate) in the novel concept of injecting high octane number fuels in partially premixed combustion. The influence of the above mentioned parameters was studied by performing
Atrial fibrillation (AF) is currently considered a risk factor for stroke. Depending on the severity of clinical factors (risk scores) a recommendation for full anticoagulation is made. Although AF is most certainly a risk factor for ischemic stroke, it is not necessarily the direct cause of it. The causality of association between AF and ischemic stroke is questioned by the reported lack of tempo
BACKGROUND: Structural anomalies of white matter are found in various brain regions of patients with schizophrenia and bipolar and other psychiatric disorders, but the causes at the cellular and molecular levels remain unclear. Oxidative stress and redox dysregulation have been proposed to play a role in the pathophysiology of several psychiatric conditions, but their anatomical and functional con
Historiografisk översikt över hur biskop Peder Winstrups roll och betydelse vid Lunds universitets tillkomst, alltifrån Winstrups egen invigningspredikan, över olika universitetshistoriska översiktsverk under 1700-, 1800- och 1900-tal till några helt nyutkomna publikationer.
The present thesis investigated how listeners use prosody to rapidly predict upcoming lexical and syntactic structures. In the first three studies, it was shown that listeners take advantage of Swedish word-level tones to pre- activate upcoming word endings. Every Swedish word has a tone on the word stem – known as a ‘word accent’ – which is either low or high, and the tone is assigned to the stem
