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REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are crucial for lineage determination and for maintaining ES cell potential. Here, we asked whether REST directly regulates neural-specifying genes in mouse ES cells using siRNA-medi
Abstract in Undetermined[Context and motivation] There is considerable flexibility in requirements specifications (both functional and non-functional), as well as in the features of available OSS components. This allows a collaborative matching and negotiation process between stakeholders such as: customers, software contractors and OSS communities, regarding desired requirements versus available
Popular Abstract in Swedish Villkoren för utbildning och undervisning förändras i väsentliga avseenden i takt med samhällets tilltagande komplexitet. Det är många gånger svårt för både lärare och elever att veta hur man på bästa sätt ska orientera sitt pedagogiska handlande. Med utgångspunkt från tre pedagogiska kontexter - grundskolan, de särskilda ungdomshemmen och grundskollärarutbildningen - pPedagogical practice is, in several important considerations, contradictory in character. In this dissertation attenention is drawn towards the field of tension that prevails between pedagogical action, which can be descibed in terms of strategic processes and communicative pedagogical action. While the former places the preconditions for effective knowledge development of the individual at the ce
Uppsatsen syftar till att söka förståelse till varför tvister mellan fackförbund om vem som ska teckna kollektivavtal uppstår. Arbetsmarknadernas parter är i allmänhet ense om att det som regel bör finnas ett kollektivavtal på varje avtalsområde. Kollektivavtalets speciella rättsverkningar gör det viktigt för fackförbunden att vara avtalspart i ett kollektivavtal. Kollektivavtalet sätter i stor utThe aim of this essay is to seek understanding about why conflicts appear between trade unions regarding which one of them should sign the collective agreement in the workplace. The labour market parties are in general in an agreement that there should only be one applicable collective agreement in every area of work. The unique effects of the collective agreement make it crucial for the trade uni
This thesis examines how learning is depicted in policy documents for public libraries on municipal and national level in Sweden. The documents analyzed are library plans from five Swedish cities, as well as the proposal for a national strategy presented in 2019 by the National Library of Sweden. The method used is Carol Bacchi’s What’s the problem represented to be-approach. Pierre Bourdieu’s the
I den här studien undersöks hur fem musiklärare som är, eller har varit, verksamma i anpassad grundskola beskriver hur de arbetar med musikalisk kunskapsutveckling, delaktighet och måluppfyllelse. Undersökningen baseras på semistrukturerade intervjuer och hela arbetet vilar på socialkonstruktivismen som vetenskapsteori. Ämnesvalet grundar sig i en nyfikenhet kring hur vi som framtida lärare kan arThis study investigates how five music teachers that are, or have been, working in Swedish compulsory school for pupils with intellectual disabilities describe how they are working with development of musical knowledge, inclusion and goal attainment. The study is conducted by using semistructured interviews and is grounded in social constructivism as its scientific theoretical framework. The selec
Rapporten behandlar arbetsmiljön vid termisk ogräsbekämpning. Metoden innebär att ogräset hettas upp med hjälp av gaslågor. Både stora fordonsburna och mindre handdrivna används. Det som från arbetsmiljösynpunkt är speciellt med metoden är de risker som är förknippade med gasolanvändningen. De allvarligaste problemen med de aggregat som studerats har varit heta och oskyddade plåtar, heta avgaser o
In temperate regions, many vector-borne parasites maximise their transmission prospects by adjusting reproduction to seasonal cycles of host susceptibility and vector availability. Nevertheless, in these regions there are areas where environmental conditions are favourable throughout the year, so that parasites could benefit from a year-round transmission strategy. We analysed how different transm
This study investigates online material published in reaction to a Science magazine report showing the absence of peer-review and editorial processes in a set of fee-charging open access journals in Biology. Quantitative and qualitative textual analyses are combined to map conceptual relations in these reactions; and to explore how understandings of scholarly communication and publishing relate to
The extent to which in-situ global mechanical tensioning (GMT) can be used to modify the residual stress state in friction stir (FS) welds is investigated in this article. Residual stress distributions have been determined by synchrotron X-ray and neutron diffraction for four sets of FS welds in high-strength AA7449-W51 and lithium containing AA2199-T8 aerospace aluminum alloys subjected to a syst
This dissertation aims to investigate and analyze people's preparation for retirement. The study has been made through semi-structured interviews with 78 people born between the years 1931-1981 regarding their preparations for retirement. The analysis is based on the model Reflexive Planning for Later Life, coping, bounded rationality, behavioural finance and the concept of governmentality, and
Current trends show that the number of people affected by natural disasters is likely to increase in coming decades. Today, more than half the world's population lives in cities and the number is expected to rise in the future. To make cities safe is therefore vital. Making Cities Resilient is an ongoing global campaign in the area of disaster risk reduction and aims to build resilient cities
The aim of this qualitative study was to investigate the social identity of students at upper secondary school for physically disabled students. The youths I drew my attention to suffered from severe physical disabilities and therefore received specially adapted education in small classes, but integrated at an ordinary upper secondary school. By "social identity" I mean how the students
The purpose of this study is to evaluate the safety of people located in discotheques in case of fire. A quantitative fire riskanalysis (QRA) for three different types of discotheques is carried out. The analysis is based on performance based codes from which fire protection alternatives are analysed. The results of the quantitative fire riskanalysis are described as risk profiles and average risk
Ett antal studier har visat att buller har negativa hälsoeffekter (Barregård et al. 2005; Rosvall et al. 2009; Nilsson, Eriksson & Palmqvist 2009). Exempel på problem som kan uppstå på grund av buller är sömnsvårigheter, hjärt- och kärlsjukdomar, minskad inlärning och reducerad kognitiv förmåga (Berglund, Lindvall & Schwela 1999). Dessa typer av hälsoproblem leder till lidande för den enskNoise has negative health effects according to a number of studies (Barregård et al. 2005; Rosvall et al. 2009; Nilsson, Eriksson & Palmqvist 2009). Example of problems that can occur from exposure to noise is sleeping disturbances, heart diseases, lessened learning and reduced cognitive performance (Berglund, Lindvall & Schwela 1999). This kind of problems cause suffering on a personal le
The purpose of this study is to examine how social service handles incorrect information about them that is spreading on social media. This study is based on a qualitative method. In order to achieve the purpose of this work, the focus has been on the unit of child protection services and seven social workers have been interviewed. The study shows that social workers only handle incorrect informat
When a country liberalizes trade through lowering taxes on imports, it stands before a number of challenges. Recovering lost trade tax revenue is one of them. Cape Verde is one of the countries that are currently negotiating an Economic Partnership Agreement with the EU and studies predict that the tariff reductions resulting from the agreement may have a severe impact on Cape Verde’s government r
Studien vände sig till personal, olika yrkesgrupper, som arbetar med krigsskadade och torterade i Sverige. Syftet var att beskriva personalgruppens mående och tillväxt i relation till arbetet, inställning till död, ondska och förlåtelse samt bakgrundsvariabler (t.ex eget trauma och arbetssituation) och undersöka samband mellan dessa. 69 traumaarbetare svarade på ett frågeformulär som mätte dessa fThe 69 participants of this study were Swedish personnel of various occupations, working at centers for war and torture survivors. The aim was to describe the personnel’s reactions from their work, their background (e.g. trauma prevalence, work situation), their attitude towards death, evil, and forgiveness and the relationships between these. The results of this study show that the participants h
