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Characterizing Ultrashort Laser Pulses With a Time-Dependent Polarization State Using the D-Scan Technique

The main idea behind the presented work is to extend the dispersion scan (d-scan) technique to measuring the time-dependent polarization state of ultrashort laser pulses. For demonstration, a rapidly varying polarization state, i.e. a polarization gate, was created from ultrashort pulses with a duration of 6 fs using a combination of wave plates. The time-dependent variation of the polarization wa

On the influence of carbides in laser-cladded coating on friction, wear, and airborne particle emissions of disc brakes

Recently, it has become a focus to reduce non-exhaust aerosol emissions from the transport sector. One possible way to decrease brake particle emissions is by laser-cladding coatings onto brake discs. This work tested five different laser-cladding coated brake discs against a non-asbestos organic brake pad. The performance of these coatings was compared to a commercial grey cast iron brake disc te

Cationic Polymer Brushes Functionalized with Carbon Dots and Boronic Acids for Bacterial Detection and Inactivation

Drug-resistant bacterial infections are among the most severe physiological challenges facing human health. Therefore, the detection and inactivation of pathogenic bacteria remains a crucial therapeutic goal in modern society. In this study, we design multifunctional nanocomposites aimed at bacterial binding, fluorescence labeling, and synergistic antibacterial treatment. These nanocomposites are

Increased prevalence of osteopenia and osteoporosis in systemic sclerosis patients, including in men and young women—a case–control study

ObjectivesTo investigate bone mineral density (BMD), osteoporosis prevalence and SSc-specific associations of BMD in SSc patients compared with background population.MethodsIn total, 211 SSc patients (182 women, 29 men; mean age 61.3 and 62.2 years, respectively) and 505 age- and sex-matched controls from the same geographic area participated. BMD and T-score at total hip and lumbar spine was meas

Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA

Prokaryotic Argonaute proteins (pAgos) from the long-A clade are stand-alone immune systems that use small interfering DNA (siDNA) guides to recognize and cleave invading plasmid and virus DNA. Certain long-A pAgos are co-encoded with accessory proteins with unknown functions. Here, we show that cyanobacterial long-A pAgos act in conjunction with Argonaute-associated Cas4 family enzyme 1 (ACE1). S

FLASH free electron laser pump-probe laser concept based on spectral broadening of high-power ytterbium picosecond systems in multi-pass cells

Within the FLASH2020+ upgrade, the pump-probe laser capabilities of the extreme ultraviolet and soft x-ray free-electron laser (XFEL) FLASH in Hamburg will be extended. In particular, providing wavelength tunability, shorter pulse durations, and reduced arrival time jitter will increase the scientific opportunities and the time resolution for the XFEL-optical laser pump-probe experiments. We prese

Energy scaling in a compact bulk multi-pass cell enabled by Laguerre-Gaussian single-vortex beams

We report pulse energy scaling enabled by the use of Laguerre-Gaussian single-vortex (LG0,l) beams for spectral broadening in a sub-40 cm long Herriott-type bulk multi-pass cell. Beams with orders l=1−3 are generated by a spatial light modulator, which facilitates rapid and precise reconfiguration of the experimental conditions. 180 fs pulses with 610 uJ pulse energy are post-compressed to 44 fs u

PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research

Prostate Cancer Diagnosis and Treatment Enhancement through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer. PIONEER brings together 34 private and public stakeholders from 9 countries in one multidisciplinary research consortium with the aim of positively transforming the field of prostate cancer clinical care by answering pressing que

Chromatic aberrations correction of attosecond high-order harmonic beams by flat-top spatial shaping of the fundamental beam

Attosecond pulses created by high-order harmonic generation in gases often exhibit strong chromatic aberrations, arising from the broad bandwidth and wavelength-dependent nonlinear light-matter interaction. When the driving laser intensity varies spatially, as for Gaussian driving beams, the apparent source position of the harmonics differs significantly from one order to the next, thus affecting

Interplay between AHR genotypes, lifestyle factors and adjuvant breast cancer treatments significantly impacts clinical outcome in a population-based cohort

BackgroundThe purpose was to evaluate the prognostic impact of aryl hydrocarbon receptor (AHR) genotypes in relation to lifestyle and adjuvant treatments in breast cancer.MethodsAHR genotyping was performed on genomic DNA from 1701 patients included 2002–2016 in Lund, Sweden, and followed for up to 15 years. Eight AHR polymorphisms and eight haplotypes were analysed using survival and interaction

Modeling Genetic Risk of β-Cell Dysfunction in Human Induced Pluripotent Stem Cells From Patients Carrying the MTNR1B Risk Variant

Disruptions in circadian rhythm, partly controlled by the hormone melatonin, increase the risk of type 2 diabetes (T2D). Accordingly, a variant of the gene encoding the melatonin receptor 1B (MTNR1B) is robustly associated with increased risk of T2D. This single-nucleotide polymorphism (SNP; rs10830963; G-allele) is an expression quantitative trait locus (eQTL) in human pancreatic islets, conferri

Static treatment of dynamic interactions in the single-orbital Anderson impurity model

Correlated electron physics is intrinsically a multiscale problem, since high-energy electronic states screen the interactions between the correlated electrons close to the Fermi level, thereby reducing the magnitude of the interaction strength and dramatically shortening its range. Thus the handling of screening is an essential ingredient in the first-principles modeling of correlated electron sy

From Strong to Weak Correlations in Breathing-Mode Kagome van der Waals Materials : Nb3(F, Cl, Br, I)8 as a Robust and Versatile Platform for Many-Body Engineering

By combining ab initio downfolding with cluster dynamical mean-field theory, we study the degree of correlations in monolayer, bilayer, and bulk breathing-mode kagome van der Waals materials Nb3(F, Cl, Br, I)8. Our new material-specific many-body model library shows that in low-temperature bulk structures the Coulomb correlation strength steadily increases from I to Br, Cl, and F, allowing us to i

Epigenetic regulation of transposable elements in human brain development and disease

Transposable elements (TEs) are mobile genetic sequences comprising around 50% of human DNA. TEs shape gene regulatory networks in development, pluripotency and inflammation, and are implicated in a number of neurological disorders. Therefore, TEs are tightly controlled by epigenetic regulators which form a complex repressive network throughout different stages of development. However, while the r

New student

IMPORTANT AND USEFUL INFORMATION FOR STUDENTS AT LUSEM Get started - 4 important stepsProgrammes and departmentsProgrammes in SwedishDates and schedulesIT (internet, printers, digital tools)LUSEM campusStudent support servicesStudent lifeImportant regulations Get started - 4 important steps 1. Activate your student account The student account gives you access to a number of electronic services tha

https://www.lusem.lu.se/study/student-web/new-student - 2026-06-01

Kurztitel

Kurztitel Kurztitel Gen41S Titel Gustav Vasas Bibel: Genesis Entstehungszeit 1540-1541 Textsorte Bibeltext Umfang 33.791 Bearbeitungsstand bis Kapitel 31, KF, 18.01.2006 Bemerkungen Korrekturen kursiv gekennzeichnet, KF, 18.01.2006 Bild durch Bild gekennzeichnet, KF, 18.01.2006 aufgelöste Kürzel kursiv gekennzeichnet, KF, 30.01.2006 [Genesis, Första Boken Mose.] [‡‡ 1a] Första Capitel. J Begynnels

https://www.nordlund.lu.se/fileadmin/user_upload/fornsvenska/rtf/Gen41SLundversion.rtf - 2026-05-24

Local scour in rivers due to bridges and natural features. A case study from Rönne river, Sweden

Broar över vattendrag utgör viktiga element i många transportsystem. Om broar kollapsar orsakas betydande problem med både direkta och indirekta kostnader för samhällsekonomin. Lokal erosion av botten kring broar är många gånger en huvudorsak till brokollaps, ofta i samband med extrema flödessituationer. Risken för sådan lokal erosion kan bli större i samband med en framtida klimatförändring, vilkBridges are important components in many transportation networks often spanning rivers and other water bodies. The failure of a bridge will cause significant direct and indirect economic losses to society. Scouring of the river bed around bridges is a principal mode of bridge failure typically associated with large floods. The risk of such scour may become higher with the emerging climate change t

Adaptor Protein LNK Is a Negative Regulator of Brain Neural Stem Cell Proliferation after Stroke.

Ischemic stroke causes transient increase of neural stem and progenitor cell (NSPC) proliferation in the subventricular zone (SVZ), and migration of newly formed neuroblasts toward the damaged area where they mature to striatal neurons. The molecular mechanisms regulating this plastic response, probably involved in structural reorganization and functional recovery, are poorly understood. The adapt