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Challenges to intra-organizational risk and vulnerability information flow in public organizations
Improving emergency response through cognitive task analysis
Society has a responsibility to aid its citizens in case of emergency. This calls for planning and preparations. However, societal emergency response activities are not always fully effective. This might be due to suboptimal emergency planning and preparations, with some planned response actions not working as intended. For example, it is possible that some actions show to be ‘over-planned’ with t
Analysing analyses – An approach to combining several risk and vulnerability analysis
Effect of a primary health-care-based controlled trial for cardiorespiratory fitness in refugee women.
BACKGROUND: Refugee women have a high risk of coronary heart disease with low physical activity as one possible mediator. Furthermore, cultural and environmental barriers to increasing physical activity have been demonstrated. The aim of the study was to evaluate the combined effect of an approximate 6-month primary health care- and community-based exercise intervention versus an individual writte
B-lymphocyte commitment: Identifying the point of no return.
Even though B-lymphocyte development is one of the best understood models for cell differentiation in the hematopoetic system, recent advances in cell sorting and functional genomics has increased this understanding further. This has suggested that already early lymphoid primed multipotent progenitor cells (LMPPs) express low levels of lymphoid restricted transcripts. The expression of these genes
Increased cartilage turnover and circulating autoantibodies in different subsets before the clinical onset of rheumatoid arthritis.
BACKGROUND: /st> Previous studies have indicated that autoantibodies may be detected years before the clinical onset of rheumatoid arthritis (RA). Cartilage biomarkers, such as cartilage oligomeric matrix protein (COMP), have not been studied previously in samples collected before the diagnosis of RA. METHODS: /st> Between 1991 and 1996, 30 447 subjects were included in the Malmö Diet Cancer Study
Impact of MDCT with intravenous contrast on the survival in patients with acute superior mesenteric artery occlusion.
Acute thromboembolic occlusion in the superior mesenteric artery (SMA) is a condition with high mortality and morbidity. Multi-detector computerised tomography with intravenous contrast enhancement (MDCTiv) may improve diagnostic accuracy and survival. Patients with acute SMA occlusion were identified between 2004 and 2008 at Malmö University Hospital, Sweden. Medical records were analysed. Each M
A clinically confirmed family history for early myocardial infarction is associated with increased risk of obesity, insulin resistance and metabolic syndrome.
OBJECTIVE:: The risk factor pattern underlying a parental history of myocardial infarction (MI) is incompletely understood. We examined whether a parental history of clinically verified early MI may promote development of insulin resistance, obesity and the metabolic syndrome (MetS). METHODS:: One hundred and seventy-four offspring to patients with clinically verified MI before 60 years of age i
Second order risk and vulnerability analyses
Artificial and sugar-sweetened beverages are associated with increased incidence of hypertension.
Progress towards Mechanism-Based Treatment for Diamond-Blackfan Anemia.
Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplastic anemia, characterized by macrocytic anemia, reticulocytopenia, and severely reduced numbers of erythroid precursors in the bone marrow. For more than fifty years, glucocorticoids have remained the main option for pharmacological treatment of DBA. While continuous glucocorticoid administration increases hemoglobin levels in a major
Preterm birth and unintentional injuries: risks to children, adolescents and young adults show no consistent pattern.
AIM: Preterm birth is associated with a number of physical and mental health issues. The aim of this study was to find out if there was also any association between individuals born preterm in Sweden between 1984 and 2006 and the risk of unintentional injuries during childhood, adolescence and young adulthood METHODS: The study followed 2,297,134 individuals, including 5.9% born preterm, from 1985
1A.10: ASSOCIATION BETWEEN GENE POLYMORPHISMS AND RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE.
Coronary heart disease (CHD) development is associated to a combination of lifestyle and genetic factors. A number of lifestyle risk factors is well defined, while genetic factors have not yet been well determined.
Diagnostikstudier bör följa internationella riktlinjer. Planering och utvärdering kräver teoretiska och praktiska överväganden.
Dual Metabolic Defects Are Required to Produce Hypertriglyceridemia in Obese Subjects
Objective-Obesity increases the risk of cardiovascular disease and premature death. However, not all obese subjects develop the metabolic abnormalities associated with obesity. The aim of this study was to clarify the mechanisms that induce dyslipidemia in obese subjects. Methods and Results-Stable isotope tracers were used to elucidate the pathophysiology of the dyslipidemia in hypertriglyceridem
Association between copeptin and declining glomerular filtration rate in people with newly diagnosed diabetes. The Skaraborg Diabetes Register.
Copeptin has shown association with development of chronic kidney disease (CKD) in people with diabetes. Early detection of individuals having the highest risk could help avoid this complication. Therefore we decided to study copeptin concentrations and estimated glomerular filtration rate (eGFR) retrospectively in people with newly diagnosed diabetes.
What Can Human Genetics Teach Us About the Causes of Cardiovascular Disease?
The longitudinal age and birth cohort trends of smoking in Sweden: a 24-year follow-up study.
The aim of this study is to analyse longitudinally, the annual effects of age group and birth cohort on smoking in the Swedish population during a 24-year period and to analyse the smoking trends for different levels of education.
Machine-learned tuning of artificial Kitaev chains from tunneling spectroscopy measurements
We demonstrate reliable machine-learned tuning of quantum-dot-based artificial Kitaev chains to Majorana sweet spots, using the covariance matrix adaptation algorithm. We show that a loss function based on local tunneling spectroscopy features of a chain with two additional sensor dots added at its ends provides a reliable metric to navigate parameter space and find points where crossed Andreev re
