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"Samtalet är som en dans där patienten för" - Om sjukhuskuratorers beskrivning av sitt arbete samt av sin kunskap och kompetens

The purpose of this study was to examine the work of clinical social workers. More specifically our aim was to perceive the knowledge and competence of clinical social workers using their own description of their work. The main questions that we address in this thesis are: How do the clinical social workers describe their knowledge and competence? What are the opinions of clinical social workers o

Synthesis and reactivity studies of model complexes for dinuclear active sites in metalloenzymes

Several new polydentate and potentially dinucleating ligands have been synthesized in order to model the coordination environments of a number of structurally related dinuclear active sites in metalloenzymes, including methane monooxygenase, the ribonucleotide reductase R2 protein, urease, arginase, red kidney bean purple acid phosphatase and zinc phosphotriesterase.~ Ligands 1 and 2 have proven t

Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress

Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e. unfolded protein response (UPR), play key roles in proteostasis but their involvement in t