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Asthma patients who continue to experience symptoms despite taking regular inhaled corticosteroids represent a management challenge. Leukotrienes play a key role in asthma pathophysiology, and since pro-inflammatory leukotrienes are poorly suppressed by corticosteroids it seems rational to add a leukotriene receptor antagonist (LTRA) when a low to moderate dose of inhaled corticosteroids does not
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The importance of the N-terminal region of human cystatin C or chicken cystatin for the kinetics of interactions of the inhibitors with four cysteine proteinases was characterized. The association rate constants for the binding of recombinant human cystatin C to papain, ficin, actinidin and recombinant rat cathepsin B were 1.1 x 10(7), 7.0 x 10(6), 2.4 x 10(6) and 1.4 x 10(6) M-1.s-1, whereas the
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This thesis contains an introductory chapter and three essays, all considering different aspects of the Swedish parental insurance. In the first two essays, different aspects of temporary parental leave (leave from work to take care of a sick child) are investigated, whereas the third essay considers parental leave (leave from work to take care of a new-born child). In the first essay, On the Sha
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The aim of this study was to investigate from the perspective of formal carers the care given to people aged 65 and over, who are cared for in their own homes by informal care. Thirty-three district nurses (DNs) and 20 home service assistants in a municipality with 13500 inhabitants (over 65 years old), were interviewed about the location of care recipients and 398 care recipients were located. Mo
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Background: Type 1 von Willebrand disease (VWD) is a congenital bleeding disorder characterized by a partial quantitative deficiency of plasma von Willebrand factor (VWF) in the absence of structural and/or functional VWF defects. Accurate assessment of the quantity and quality of plasma VWF is difficult but is a prerequisite for correct classification. Objective: To evaluate the proportion of mis
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Background Ximelagatran is a novel, oral direct thrombin inhibitor under investigation as an alternative to warfarin for prevention of thromboembolism in patients with nonvalvular atrial fibrillation (AF). Two long-term studies in patients with AF and at least one additional risk factor for stroke are underway to compare the safety and efficacy of fixed-dose ximelagatran (36 mg bid) without coagu
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Mantle cell lymphoma (MCL) is a heterogenic non-Hodgkin lymphoma entity, with a median survival of about 5 years. In 2008 we reported the early based on the median observation time of 4 years results of the Nordic Lymphoma Group MCL2 study of frontline intensive induction immunochemotherapy and autologous stem cell transplantation (ASCT), with more than 60% event-free survival at 5 years, and no s
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Moving into a nursing home is a significant transition for older people which can be emotional and stressful. The literature on the decision to move and subsequent residential stress focuses on the time after admission; however, there is less understanding of older people’s management of the process. To fully understand and possibly reduce negative consequences and health-related risks, the aim of
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Focussing on the public school in early modern Sweden, this articleinvestigates the role of the Aesopic fable in elementary education in Greek. Asa background, the solid position of fable as genre in the teaching of Latin inmedieval Europe is sketched. When humanism launched Greek as schoolsubject, fable was adopted as reading material in the teaching of the newlanguage, partly for the same reason
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Almost half of all divorced Swedes are aged 60+ and many of them are, or have been, part of a reconstituted family. This increases the probability of having (or to be a) bonus/step-grandchild and raises the question: How does the caregiving dynamic between bonus-grandparents and bonus-grandchildren intersect with gender and life situation, unraveling the intricate threads that weave through familAlmost half of all divorced Swedes are aged 60+ and many of them are, or have been, part of a reconstituted family. This increases the probability of having (or to be a) bonus/step-grandchild and raises the question: How does the caregiving dynamic between bonus-grandparents and bonus-grandchildren intersect with gender and life situation, unraveling the intricate threads that weave through famil
Three African Courts Meeting to Exchange Knowledge - The Raoul Wallenberg Institute of Human Rights
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Sveriges framtida elsystem står inför en stor omställning, där kärnkraft successivt kommer att fasas ut, samtidigt som det sker en stor utbyggnad av vindkraft. Vindkraftens sjunkande priser, tillsammans med Sveriges mål om ett 100 % förnybart elsystem år 2040, gör det till en attraktiv resurs. En omställning från en leveranstrygg elproduktion baserad på kärnkraft, till en mer variabel med vindkrafSweden's future electricity system is facing a transformation, where nuclear power will gradually be phased out, while there is a large expansion of wind power. The declining wind power prices, together with Sweden's goal of a 100% renewable electricity system in 2040, makes it an attractive resource. However, a change from a secure supply of energy from nuclear production, to a more varia
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The aim of this study was to examine volunteers’ experiences of voluntary work with Roma people in Romania, and what impact it might have given the volunteers. To answer this, we used a qualitative method were we interviewed six volunteers who had been working as volunteers in Romania. Our conclusion is that the volunteers learned by being “on location” and that their experiences made an impact in
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The rapid globalization has led to a rise in the number of multinational corporations. One common objective among these corporations when expanding to other developed markets is to access intangible resources such as knowledge. Through the acquisition of knowledge, corporations can strengthen their strategic position and improve their competitiveness. When operating across national borders, variou
