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Xenopus is a favorable experimental model in developmental biology. With its fast and external development, high number of progeny and large size, early embryos are well suited for micromanipulation to study the function of genes with relevance to human diseases. In this chapter, we present a combined method for lineage tracing and whole-mount in situ hybridization. In addition, we present protoco
Brain-derived neurotrophic factor (BDNF) is an important protein for neuroplasticity and neurogenesis. In this thesis the role of BDNF, in suicidal behaviour was investigated with focus on possible risk factors for suicidal behaviour such as avoidant focused coping, dysfuntional personality traits like impulsiveness and hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis.Paper I: The a
The aim of this thesis is to explore the evolution of new technology-based firms (NTBFs) based on solid empirical material for the Swedish economy. NTBFs are argued to be one important type of entrepreneurial firms that contribute to technology change, knowledge spillovers, and economic growth. However, our knowledge concerning how NTBFs exert their technological and economic influences is far fro
The Arctic-Boreal region is projected to experience spatially divergent trends in snow depth following climate change. However, the impact of these spatial trends has remained largely unexplored, despite potentially large consequences for the carbon cycle. To address this knowledge gap, we forced a customised arctic version of the dynamic vegetation model LPJ-GUESS with daily CMIP6 outputs from a
This article intends to raise questions related to nationalism in South Asia, while also addressing the rationale for this special issue. Is nationalism a monolithic construct based on a European precedent or is it something much larger that is developed pluralistically in a variety of contexts around the world? If the latter is true, which is our position, then how do we go about studying the var
Regions around the world employ cluster-based policies as part of their industrial, innovation and development policy mixes. They have become a key tool in smart specialisation strategies and are increasingly used to address societal challenges. Given their popularity and longevity, there is significant demand to better measure and understand the impacts of cluster policies. Yet the diversity of cRegions around the world employ cluster-based policies as part of their industrial, innovation and development policy mixes. They have become a key tool in smart specialisation strategies and are increasingly used to address societal challenges. Given their popularity and longevity, there is significant demand to better measure and understand the impacts of cluster policies. Yet the diversity of c
The multi-electrode electrical resistivity method has become one of the most efficient geophysical methods used in a wide range of applications, which is also suitable when disturbances in the ground are to be avoided. The selection of the right electrode configuration can provide better effectiveness, depending on the target being investigated. In this work a case of the use of three electrode arThe multi-electrode electrical resistivity method has become one of the most efficient geophysical methods used in a wide range of applications, which is also suitable when disturbances in the ground are to be avoided. The selection of the right electrode configuration can provide better effectiveness, depending on the target being investigated. In this work a case of the use of three electrode ar
Our current historical moment is marked by a widespread sense of (ongoing and anticipated) crises, prompting calls to change existing economic, political, social, and environmental systems. This discourse has directed increased scholarly and policy-orientated attention to the concepts of “transformation” and “resilience.” However,beyond attention, these concepts have increasingly adopted a place iOur current historical moment is marked by a widespread sense of (ongoing and anticipated) crises, prompting calls to change existing economic, political, social, and environmental systems. This discourse has directed increased scholarly and policy-orientated attention to the concepts of “transformation” and “resilience.” However, beyond attention, these concepts have increasingly adopted a place
On the basis of ethnographic fieldwork in Singapore, the article explores the tension between children's academic success and emotional wellbeing, and the ways in which middle-class parents navigate these conflicting aspirations. It delves into families with young children who pursue alternative lifestyles by moving abroad to a presumably less stressful environment or by homeschooling their childrOn the basis of ethnographic fieldwork in Singapore, the article explores the tension between children's academic success and emotional wellbeing, and the ways in which middle-class parents navigate these conflicting aspirations. It delves into families with young children who pursue alternative lifestyles by moving abroad to a presumably less stressful environment or by homeschooling their childr
Although the information obtained from in vivo proton magnetic resonance spectroscopy (1H MRS) presents a complex-valued spectrum, spectral quantification generally employs linear combination model (LCM) fitting using the real spectrum alone. There is currently no known investigation comparing fit results obtained from LCM fitting over the full complex data versus the real data and how these resulAlthough the information obtained from in vivo proton magnetic resonance spectroscopy (1H MRS) presents a complex-valued spectrum, spectral quantification generally employs linear combination model (LCM) fitting using the real spectrum alone. There is currently no known investigation comparing fit results obtained from LCM fitting over the full complex data versus the real data and how these resul
BACKGROUND AND AIM: In many places worldwide there is an ongoing urbanization, often achieved through densification. An increased number of inhabitants in an area often leads to both increased traffic and placement of new buildings closer to roads, and thus increased population exposure to road traffic noise. The aim of the study was to estimate and compare the health impacts of road traffic noise
IntroductionInternet-based interventions are called for within rehabilitation to meet the limited access to support for self-management after stroke. Therefore, a new intervention program, “Strategies for Empowering activities in Everyday life” (SEE) was developed. The aim of this study was to explore and describe how clients with stroke and their occupational therapists experienced the SEE interv
Introduction: Older adults spend more time at home after retirement, and the home becomes a central place for activity. While research indicates that indoor lighting, exposure to daylight, physical activity and sleep interact to influence functioning, mood and daily rhythm, strategies are needed to promote behavioural changes to optimise these factors in daily life. The objective is to design an i
The purpose of this project was to investigate how the interior of a future autonomous truck can be designed with a user friendly focus. The solution should be suitable for a future scenario in 2030 where a Volvo FH with automation level 4 on the SAE scale will drive the route from Gothenburg to Umeå. This means that the truck is fully autonomous but there has to be a driver in the cab that can dr
The popularity of the Netflix series ‘Drive To Survive’ has almost doubled the amount of Formula 1 (F1) fans thanks to its great storytelling and compelling narratives about the drivers, teams, the rivalries between them and challenges they tackle. The first season aired in 2019 and it is estimated that more than 6.8 million people have watched the show. As a result, the F1 brand is stronger than
Current post-carbon transition trajectories are primarily based on a belief in technical solutions wherein considerations of the citizens’ role in collective mobilisation and transformation are largely overlooked. To this end, the thesis seeks to understand how citizens can become active agents of change within transition efforts and how their political agency can be empowered accordingly. This, b
