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Popular Abstract in Swedish Arbetet med denna avhandling har handlat om en abnormal fosfolipid (fettämne) som bildas i kroppens celler endast när alkohol är närvarande, lipiden kallas fosfatidyletanol (PEth). För att lättare kunna förstå resultaten av våra undersökningar börjar jag med en kort bakgrund. Alla kroppens celler är omgärdade av ett membran som skiljer dem från varandra och omgivningen.Phosphatidylethanol (PEth) is an abnormal phospholipid formed exclusively by the action of phospholipase D (PLD) in the presence of ethanol. The degradation of PEth is slow and due to its accumulation in some cells the possibility to use PEth as marker of ethanol intake has been proposed. It has also been suggested that PEth mediates some of the damaging effects of ethanol on cells. This study was

I den här boken visar författaren hur flera historiska och teologiska faktorer samverkat till att skapa bilden av motsatsförhållandet mellan judendom och kristendom, vilket starkt bidragit till den idétradition som möjliggjorde Förintelsen och som fortfarande lever kvar inom kyrka och akademi. Enligt den traditionella synen har kristendomen uppfattats som judendomens definitiva motsats. Vanligtvis

In this essay, I discovered what made Sweden change its course regarding refugee policy between 1942 and 1943. My oral family history has raised my interest in finding out what made Sweden change that course and if, before the change, the Norwegian Jews were rejected where other groups weren’t. This was done using the method ’Most Similar System Design’ by Mills. I compare Sweden with Sweden with

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort Ashok Sharma1, Xiang Liu2, David Hadley3, William Hagopian4, Wei-Min Chen5, Suna Onengut-Gumuscu5, Carina Törn6, Andrea K. Steck7, B

https://www.teddy.lu.se/sites/teddy.lu.se/files/identification_of_non-hla_genes_associated_with_development_of_islet.pdf - 2026-05-19

Ökning i sydliga lövsångares flyttningsbeteende Fåglars flyttning har länge fascinerat människan och kanske framförallt småfåglars flyttning. Hur kan t. ex. en lövsångare, Phylloscopus trochilus, på 10 gram som föddes för några månader sedan hitta hela vägen ner till övervintringsområdena i Afrika, dessutom helt utan hjälp av andra? Sedan länge är det känt att svaret verkar ligga i deras gener mDifferences in migratory behaviour has long been suggested to potentially drive speciation, but the genetics underlying this process remains a mystery. Studies of hybrid zones between two closely related taxa with contrasting migratory phenotypes, called migratory divides, have played a crucial role for our understanding of how such differences can lead to reproductive isolation. Movements of hybr

Många städer runt om i världen står inför samma utmaningar när det gäller kvinnors förmåga att röra sig och känna sig trygga i offentliga utrymmen. För kvinnor innebär användningen av offentliga utrymmen rädsla för sexuellt våld och för att bli attackerade, vilket tvingar dem att alltid vara vaksamma och minskar deras livskvalitet. Genom historien har städer planerats av främst manliga planerare,Many cities around the world are facing the same challenges when it comes to the ability for women to move around and feel safe in public spaces. For women, using public spaces entails fear of sexual violence and of being attacked, which forces them to always be vigilant and reduces their quality of life. Throughout history, cities have consisted of mainly male planners, designers and government

Tissue engineering strategies predominantly rely on the production of living substitutes, whereby implanted cells actively participate in the regenerative process. Beyond cost and delayed graft availability, the patient-specific performance of engineered tissues poses serious concerns on their clinical translation ability. A more exciting paradigm consists in exploiting cell-laid, engineered extra

Aims T cells are present in atrial tissue from atrial fibrillation (AF) patients. However, prospective studies of T cells and AF development are few. The current aim was to investigate if T-cell subsets are associated with the risk of developing AF. Methods and results T-cell subsets, measured by flow cytometry of cryopreserved mononuclear leucocytes isolated from blood at baseline, were analysed

Background: Despite substantial progress in the field of mass spectrometry, there remain barriers to measuring the extracellular vesicles (EVs) proteome in blood plasma. Recent work has shown that isolating EVs can make it possible to detect proteins that have low abundance in plasma. Commonly used EV isolation methods either require large sample volumes and long ultracentrifugation times, or else

At the emergency department, it is important to quickly and accurately identify patients at risk of acute myocardial infarction (AMI). One of the main tools for detecting AMI is the electrocardiogram (ECG), which can be difficult to interpret manually. There is a long history of applying machine learning algorithms to ECGs, but such algorithms are quite data hungry, and correctly labeled high-qual

OBJECTIVE: To investigate a recently developed MRI technique for mapping the Mean Diffusivity of Tissue (MDT), which improves diffusion MRI imaging of the cerebral cortex by reducing partial volume effects from cerebrospinal fluid (CSF). As cortical lesions are common in patients with focal epilepsy, we explored the clinical value of MDT imaging in patients with drug resistant epilepsy and low-gra

INTRODUCTION: We assessed the accuracy of the Amsterdam Instrumental Activities of Daily Living Questionnaire (A-IADL-Q) for clinical staging in Swedish primary care.METHODS: Participants from the Swedish BioFINDER Primary Care study were included. Discriminative performance of the A-IADL-Q was evaluated using receiver operating curves. Multinomial and linear regression models assessed association

In recent years, Iceland has experienced a growing demand for residential housing and the average square-meter price for apartments and single-family homes in the Capital Region has almost doubled between 2010 and 2019. Property sales in Iceland are most commonly intermediated by real estate brokers and the sales process stands in contrast to other Nordic countries, since it involves a bidding pro