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Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

OBJECTIVE-The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic beta-cell function by potentiating insulin secretion and beta-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR)

Key issues for companies entering the Chinese WEEE recycling industry

Problem: The Chinese WEEE recycling market is today operated mostly by the informal sector. As this sector eludes the insufficiently enforced environmental laws the e-waste is recycled by means not only harmful to the environment and people working with the recycling process, but it also utilizes methods that do not recover valuable materials in a sound and efficient way. Many companies stand read

Analysis of background noise and boats noise detection in coastal areas

The underwater noise has a significant negative impact on marine animals. The EU has made efforts to keep noise emission within sustainable limits, but only in regards to boats with Automatic Identification System (AIS). The noise of recreational boats, which are the main noise emitter in coastal areas, is overlooked. Thus, there is a need to quantify the noise emitted by recreational boats and, iStudies have shown that the underwater noise undoubtedly has a negative impact on marine animals. The EU have made efforts to keep the noise emission within sustainable limits, but mainly in regards to commercial freight ships. This means that noise from recreational boats, which are the main noise emitter in coastal areas, are overlooked. The noise from recreational boats is also under-investigat

Linguistic and Syllabic Embeddings as Predictors in Auditory Attention Decoding

The human brain has a built-in capacity to perform selective hearing, allowing us to focus on a single speaker in noisy environments while subconsciously filtering out background chatter and other noise. This ability is colloquially known as the cocktail party effect and is often impaired in individuals with reduced hearing or other neurological conditions. This results in an overall reduced quali

Konstruktiva relationer och länkade aktiviteter : Att utforma föreläsningar med mer studentaktivitet och tydligare konstruktiv länkning

Konstruktiv länkning, studentaktivitet och föreläsningar är tre grundstenar i högre utbildning. Men föreläsningen som undervisningsform har kritiserats: ”Det finns gott om högskolepedagogisk litteratur som förklarar varför föreläsningen är olämplig för att stimulera lärande. Ändå fortsätter vi föreläsa”, skriver Andreas Håkansson (2017, s. 40) i en artikel som trots allt landar i att denna undervi

The effect of apple fermentation on bioactive compounds and microorganism composition

Fermentering av äpple - På gott och ont Fermentation, eller jäsning, av mat och dryck har varit känt under tusentals år. Fördelarna med fermenterade livsmedel är bl. a. att de blir mer lättsmälta, innehåller fler syntetiserade näringsämnen, minskar eller tar bort sjukdomsalstrande bakterier (patogener) samt ökar den probiotiska floran i tarmen. Under fermenteringen kan det skapas etanol - den mes

Photoemission Electron Microscopy for Ultrafast Nano-Optics - Femtoseconds to Attoseconds

Popular Abstract in Swedish Nanotekniken håller i skrivande stund på att revolutionera samhället med nya innovationer inom exempelvis elektronik och medicin. En viktig del i detta är utvecklingen av nya och förbättrade sätt att avbilda strukturer av nanometerstorlek (en nanometer är en miljarddels meter). Avancerade karakteriseringsmetoder skapar en ökad förståelse för hur nanostrukturer beter sigUltrafast nano-optics is a new and quickly evolving research field centred around the control, manipulation, and application of light on a nanometre and femtosecond scale. This can lead to improved electro-optical devices, more sensitive spectroscopy, and real-time control of chemical reactions. However, understanding the simultaneous nanometre and femtosecond evolution of nano-optical fields requ

ALICE upgrades during the LHC Long Shutdown 2

A Large Ion Collider Experiment (ALICE) has been conceived and constructed as a heavy-ion experiment at the LHC. During LHC Runs 1 and 2, it has produced a wide range of physics results using all collision systems available at the LHC. In order to best exploit new physics opportunities opening up with the upgraded LHC and new detector technologies, the experiment has undergone a major upgrade duri

The evolution of lepidopteran brain morphology

Animals live in diverse environments and have evolved to cope with environmental challenges in different ways. How such adaptations shape overall brain morphology is still unclear. Here, we test how two behavioural adaptations – circadian activity pattern and migratory behaviour – are reflected in the brains of moths and butterflies (Lepidoptera). We predicted that circadian activity pattern affec

Ur led är tiden. En studie av hur tid skildras i filmer med fokus på hur filmerna Arrival och Interstellar utmanar vår tidsuppfattning

This thesis explores how time is represented in movies. It focuses on the challenges and possibilities that faces both the filmmakers and the audience in creating and interpreting a timeline. The investigation begins with a study of narrative tools used in movies that are characterised by a traditional, linear timeline where events are linked by cause and effect and continues with an investigation

Distributed treasure - island economies 2010

Microsoft Word - introduction to report to be proofread-picture-final.doc   Distributed Treasure - Island Economies - nicolas acosta • yunwen bai • ole bondesen • amy cregar emily dowding-smith •jana kovandzic •xiao li neisha manickchand • arijit paul • galyna prymak maria rosell•mark ryan •raquel salazar•anton smit The International Institute for Industrial Environmental Economics at Lund Univers

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/distributed_treasure_-_island_economies_2010.pdf - 2026-05-16

Nuclear Nonproliferation Objectives of Permanence with Accountability at Stake : The Role of International Law in the Interlude Between the Tenth and the Eleventh Review Conference of the Parties to the Treaty on the Non-proliferation of Nuclear Weapons

This chapter aims to discuss the meaning and implication, in terms of international law, of the concept of permanence with accountability in the framework of the tenth Review Conference of the States party to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) and in the interval between this and the next Review Conference. After contextualizing the concept of permanence with accountabili

Abstract P4-09-03: On the development and clinical value of RNA-sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: A report from the population-based multicenter SCAN-B study

Background:In early breast cancer, five histopathological biomarkers are part of current clinical routines and used for determining prognosis and treatment: estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (ERBB2/HER2), Ki67, and Nottingham histological grade (NHG). We aimed to develop classifiers for these biomarkers based on tumor mRNA-sequencing (RNA

High Levels of Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Carotid Plaque Inflammation and Increased Risk of Ischemic Stroke

Background When the lectinlike oxidized low-density lipoprotein (ox LDL) receptor-1 ( LOX -1), a scavenger receptor for ox LDL , binds ox LDL , processes leading to endothelial dysfunction and inflammation are promoted. We aimed to study release mechanisms of LOX -1 and how circulating levels of soluble LOX -1 ( sLOX -1) relate to plaque inflammation and future risk for ischemic stroke. Methods an

Severe intestinal dysbiosis is prevalent in primary Sjögren's syndrome and is associated with systemic disease activity.

BACKGROUND: Altered microbial composition of the intestine, commonly referred to as dysbiosis, has been associated with several autoimmune diseases including primary Sjögren's syndrome (pSS). The aims of the current study were to study the intestinal microbial balance in pSS and to identify clinical features associated with dysbiosis.METHODS: Forty-two consecutive pSS patients and 35 age-matched aAltered microbial composition of the intestine, commonly referred to as dysbiosis, has been associated with several autoimmune diseases including primary Sjögren’s syndrome (pSS). The aims of the current study were to study the intestinal microbial balance in pSS and to identify clinical features associated with dysbiosis.

Possibilities with Probabilistic Methods for Dynamic Building Energy Simulations using Stochastic Input Data : – Initial Analysis

As observed in earlier studies, there is evidently a performance gap between the predicted annual energy use from building performance simulations basedon traditional deterministic methods compared to the monitored annual energy use of a building. The hypothesis is that using a probabilistic method makes it possible to consider the uncertainties in the input data and quantify the overall uncertainAs observed in earlier studies, there is evidently a performance gap between the predicted annual energy use from building performance simulations based on traditional deterministic methods compared to the monitored annual energy use of a building. The hypothesis is that using a probabilistic method makes it possible to consider the uncertainties in the input data and quantify the overall uncertai

Increased pulmonary blood volume variation in patients with heart failure compared to healthy controls; a non-invasive, quantitative measure of heart failure

Variation of the blood content of the pulmonary vascular bed during a heartbeat can be quantified by pulmonary blood volume variation (PBVV) using magnetic resonance imaging (MRI). The aim was to evaluate if PBVV differs in patients with heart failure compared to healthy controls and investigate the mechanisms behind the PBVV. Forty-six patients and 10 controls underwent MRI. PBVV was calculated f