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Flow and noise investigations of a separate flow exhaust system

A major component of aircraft noise is the jet noise created by the high velocity hot stream exhausting from a jet engine, interacting with itself and with the surrounding cold air. In the present paper the flow and acoustic fields that are generated by two coaxial jets are considered. Numerically, the problem is divided into a flow related part (Navier-Stokes system of equation) and an acoustic p

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development, but the relative importance of different cellular sources of PDGFB has not been established. Using Cre-lox techniques, we show here that genetic ablation of Pdgfb in endothelial cells leads to impaired recruitment of pericytes to blood vessels. The endothelium-restricted Pdgfb knockout mutants also develop

Traffic conflicts analyses for 2+1 road sections

The additional passing lanes and 2+1 roads improve significant road safety. Studies indicate sections with additional passing lanes (relief or alternately), which may cause reduction in the number of accidents by 50%. However, how geometric design affects the safety performance of such sections is not in depth investigated. Previous studies are carried out with two approaches, i.e. the most often,

”Ett osedligt och förargelseväckande uppträde” : Carl Lindell och 1884 års likkisteincident

Goda kamrater, ett antal buteljer punsch, en droska, och en likkista av barnmodell – vad är det värsta som kan hända? I lundastudenten Carl Lindells fall slutade det riktigt illa, med både tidningsskriverier och rektorsförhör. Arkivarien vid universitetsarkivet Henrik Ullstad berättar historien om en Malmöutflykt på 1880-talet som tog en ände med förskräckelse.Good companions, numerous bottles of punsch, a carriage and a child-sized coffin – what could possibly go wrong? In the case of Lund student Carl Lindell, it all went horribly wrong, with stories in the newspapers and being taken before the vice-chancellor. University Library archivist, Henrik Ullstad, tells the story of a Malmö excursion in the 1880s that came to an alarming end.

Rapid response team activation prior to in-hospital cardiac arrest : Areas for improvements based on a national cohort study

INTRODUCTION: Rapid response teams (RRTs) are designed to improve the "chain of prevention" of in-hospital cardiac arrest (IHCA). We studied the 30-day survival of patients reviewed by RRTs within 24 hours prior to IHCA, as compared to patients not reviewed by RRTs.METHODS: A nationwide cohort study based on the Swedish Registry of Cardiopulmonary Resuscitation, between January 1st, 2014, and Dece

Preserving the past to serve the future : Lilli Zickerman’s inventory of textile handicrafts 1914–1931

Lilli Zickerman (1858–1949) was an entrepreneur who took part in organising the Swedish handicraft associations in the late 19th century. She was also a pioneer in the archives and active in the feminine sphere of textile handicraft. From 1914–1931 she conducted a huge inventory called Swedish Folk Textile Art that consists of more than 24,000 photographs and descriptions of vernacular textiles an

A robust Bayesian bias-adjusted random effects model for consideration of uncertainty about bias terms in evidence synthesis

Meta-analysis is a statistical method used in evidence synthesis for combining, analyzing and summarizing studies that have the same target endpoint and aims to derive a pooled quantitative estimate using fixed and random effects models or network models. Differences among included studies depend on variations in target populations (ie, heterogeneity) and variations in study quality due to study d

Targeted plasma metabolomics in resuscitated comatose out-of-hospital cardiac arrest patients

Background: Out-of-hospital cardiac arrest (OHCA) is a leading cause of death. Even if successfully resuscitated, mortality remains high due to ischemic and reperfusion injury (I/R). The oxygen deprivation leads to a metabolic derangement amplified upon reperfusion resulting in an uncontrolled generation of reactive oxygen species in the mitochondria triggering cell death mechanisms. The understan

State Provision of Resilience in Social Compulsory Care : A Vulnerability Analysis of Physical Constraint of Children and Youth Without Consent

Children’s and young persons’ rights have received increasing been focus in recent decades, due in a significant degree to the UN Convention on the Rights of the Child. In Sweden, compulsory care in the social-services system is disputed, not least for the forceful measures that facility personnel have at their disposal to control children in certain conflict situations. The general aim of this ar

Electronic pedagogy and future university business models

Based on the International Conference on Information Systems’ (ICIS) 2014 senior scholars’ forum, we share insights on the relationship between evolving university business models and the adoption of electronic pedagogy. In recent years, particularly with the initiation of MOOCs, the potential for delivering high-quality and widely distributed coursework has expanded. However, particular instances

Improvement in self-reported cognitive functioning but not in rumination following online working memory training in a two-year follow-up study of remitted major depressive disorder

Self-reported subjective cognitive difficulties (subjective deficits) and rumination are central residual cognitive symptoms following major depressive disorder (MDD). These are risk factors for more a severe course of illness, and despite the considerable relapse risk of MDD, few interventions target the remitted phase, a high-risk period for developing new episodes. Online distribution of interv

Prolonged and intense neuroinflammation after severe traumatic brain injury assessed by cerebral microdialysis with 300 kDa membranes

Background: A neuroinflammatory response that may lead to edema and secondary brain damage is elicited in severe traumatic brain injury (TBI). Previous studies using microdialysis (MD) membranes with 100 k Dalton (kDa) cut-off found a transient intracerebral release of cytokines and chemokines without significant correlations to clinical course, intracranial pressure (ICP) or metabolites. In this