Search results

OBJECTIVE-The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic beta-cell function by potentiating insulin secretion and beta-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR)

The liberty of religion is not easy to define or regulate. It is closely connected to other liberties and rights. Starting from individual liberty, the consequence will be a right to religion or from religion, the right to change religion or confession, and the right to transition from religion to no religion, or from no religion to religion. It is obvious that the state, the religious denominatio

B-cell lymphoma (BCL) heterogeneity represents a key issue, often making the classification and clinical management of these patients challenging. In this pilot study, we outlined the first resolved view of BCL disease heterogeneity on the protein level by deciphering disease-associated plasma biomarkers, specific for chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma

We are living in a highly dynamic, human-dominated Earth System in which non-linear, abrupt and irreversible changes are not only possible but also probable. These changes require institutional structures capable of steering human society away from critical tipping points and irreversible change and ensuring sustainable livelihoods for all. We see 2012 as a charter moment, a historic opportunity t

Purpose - H2O, CO2 and CO are three main species in combustion systems which have high volume fractions. In addition, soot has strong absorption in the infrared band. Thus, H2O, CO2, CO and soot may take important roles in radiative heat transfer. To provide calculations with high accuracy, all of the participating media should be considered non-gray media. Thus, the purpose of this paper is to st

A sorption isotherm expresses the relation between ambient relative humidity (RH) and equilibrium moisture content of a material for a specific temperature. The sorption isotherm can generally be divided into a hygroscopic part covering low, medium and high RH levels, and an over-hygroscopic part close to 100% RH. For wood, the hygroscopic part is dominated by water uptake in cell walls and the ov

A machine-learning and a string-matching approach to automated subject classification of text were compared, as to their performance, advantages and downsides. The former approach was based on an SVM algorithm, while the latter comprised string-matching between a controlled vocabulary and words in the text to be classified. Data collection consisted of a subset from Compendex, classified into six

This case-control study of tobacco smoking and acute myeloid leukemia (AML), emphasizing specific associations with morphologic and cytogenetic subtypes, comprised smoking histories for 333 cases and 351 controls. Smoking status (ever smokers versus life-long non-smokers) showed no evident effect on AML risk. However, an effect of smoking was indicated at high cumulative smoking doses (pack-years)

Physicochemical properties of solutions of charged colloids are often dominated by the electrostatic interactions present in such systems. A full determination of these properties constitutes a highly nontrivial many-body problem involving long-range interactions. In electrostatically strongly coupled systems, it is essential to explicitly include both the charged colloids and the small ions in th