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Den samtida receptionen och värderingen av AI-genererad litteratur i Sverige

In this article, we analyze the reception of the AI-generated poetry collection Ammaseus horisont: AI tolkar Karin Boye (2020) and discuss the more general debate about AI-generated literature in the Swedish press since November 2022, when OpenAI made ChatGPT available to the public. Specifically, we analyze the ways in which Swedish critics construct the literary value of Ammaseus horisont and un

Comprehensive multifaceted analysis for unveiling the driving factors of groundwater decline

Groundwater, as a vital water resource in arid and semi-arid regions, plays a crucial role in sustaining human livelihoods, agriculture, and industry. Over recent decades, these areas have witnessed rapid groundwater depletion, raising concerns about resource sustainability. This research provides a comprehensive analysis of the factors contributing to the decline in groundwater levels (GWL) withi

Multinodal Acoustic Trapping Enables High Capacity and High Throughput Enrichment of Extracellular Vesicles and Microparticles in miRNA and MS Proteomics Studies

We report a new design of an acoustophoretic trapping device with significantly increased capacity and throughput, compared to current commercial acoustic trapping systems. Acoustic trapping enables nanoparticle and extracellular vesicle (EV) enrichment without ultracentrifugation. Current commercial acoustic trapping technology uses an acoustic single-node resonance and typically operates at flow

An Arrest in the US Shows the Islamic Republic’s Influence in the West

The FBI recently arrested an Iranian academic for failing to register as a foreign agent in accordance with the Foreign Agents Registration Act. Kaveh Afrasiabi was arrested in Massachusetts and is believed to have received more than $250,000 from the Iranian regime to disseminate its propaganda in the guise of objective analysis. Iranian agent-scholars are easy to recognize: they always oppose th

IFN-β rescues neurodegeneration by regulating mitochondrial fission via STAT5, PGAM5, and Drp1

Mitochondrial homeostasis is essential for providing cellular energy, particularly in resource-demanding neurons, defects in which cause neurodegeneration, but the function of interferons (IFNs) in regulating neuronal mitochondrial homeostasis is unknown. We found that neuronal IFN-β is indispensable for mitochondrial homeostasis and metabolism, sustaining ATP levels and preventing excessive ROS b

The impact of mothers. Intergenerational mobility in Sweden 1865-2015

How does parental social status affects child status attainment across time? Social mobility studies have traditionally studied parent-child associations using one ‘dominant’ parent to reflect social origin. However, the institutions of family and work have changed substantially over the past 150 years, in Sweden as elsewhere. These changes are associated with changes in intergenerationalstatus mo

Principles of Radiological Protection in Healthcare

The use of ionizing radiation and radioactive substances for diagnostic, interventional and therapeutic procedures in health care provides benefits to millions of people each year. Since ionizing radiation also has harmful effects, a radiation protection approach is needed. The International Commission on Radiological Protection (ICRP) has formulated the primary aim of radiation protection in gene

Osteomodulin Gene Expression Is Associated with Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort

Background: Stable atherosclerotic plaques are characterized by thick fibrous caps of smooth muscle cells, collagen, and macrocalcifications. Identifying factors of plaque stability is necessary to design drugs to prevent plaque rupture and symptoms. Osteomodulin, originally identified in bones, is expressed by bone synthesizing osteoblasts and involved in mineralization. In the present study, we

In vivo dendritic cell reprogramming for cancer immunotherapy

Immunotherapy can lead to long-term survival for some cancer patients, yet generalized success has been hampered by insufficient antigen presentation and exclusion of immunogenic cells from the tumor microenvironment. Here, we developed an approach to reprogram tumor cells in vivo by adenoviral delivery of the transcription factors PU.1, IRF8, and BATF3, which enabled them to present antigens as t

T-cell commitment inheritance—an agent-based multi-scale model

T-cell development provides an excellent model system for studying lineage commitment from a multipotent progenitor. The intrathymic development process has been thoroughly studied. The molecular circuitry controlling it has been dissected and the necessary steps like programmed shut off of progenitor genes and T-cell genes upregulation have been revealed. However, the exact timing between decisio

Floating charges in the Nordic countries

This chapter analyses floating charges in the Nordic countries, focusing on Denmark, Norway, Sweden and Finland. Nordic property laws are known for their functional approach, and while property law rules in the Nordic countries are generally fragmentary, Nordic security rights laws are more codified. The four Nordic countries all have floating charges (or equivalent security rights). The chapter d

Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes

Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants remain inadequately understood. In this study, we report a genome-wide association study of HF and its subtypes in a sample of 1.9 million individuals. A total of 153,174 individual

Polystyrene Nanoplastic Exposure Promotes Amyloid Misfolding and Metabolic Impairment at Sub-Lethal Doses. A Subcellular Infrared Imaging Study

Microplastics and nanoplastics (MNPs) are ubiquitous environmental pollutants with increasing implications for human health. While their presence in human tissues is established, the molecular mechanisms driving their potential neurotoxicity remain unclear. This study investigates the impact of polystyrene (PS) on amyloid protein misfolding and cellular metabolism using Optical Photothermal Infrar

The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease

Transplantation of human fetal ventral mesencephalic tissue in individuals with Parkinson's disease has yielded clinical benefits but also side effects, such as graft-induced dyskinesias. The open-label TransEuro trial ( NCT01898390 ) was designed to determine whether this approach could be further developed into a clinically useful treatment. Owing to poor availability of human fetal ventral mese