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Prostate cancer is the most diagnosed cancer in men. The diagnosis is confirmed by pathologists based on ocular inspection of prostate biopsies in order to classify them according to Gleason score. The main goal of this paper is to automate the classification using convolutional neural networks (CNNs). The introduction of CNNs has broadened the field of pattern recognition. It replaces the classic

The search for new cancer biomarkers is essential for fundamental research, diagnostics, as well as for patient treatment and monitoring. Whereas most cancer biomarkers are biomolecules, an increasing number of studies show that mechanical cues are promising biomarker candidates. Although cell deformability has been shown to be a possible cancer biomarker, cellular forces as cancer biomarkers have

Brottmekaniska processer ar något som intresserat människor i alla tider. Ibland har det varit för att vinna en fördel t ex vid tillverking av flintverktyg och malmbrytning, men oftast for att förhindra mekanisk kollaps. I det senare fallet kan oförsiktighet resultera i spruckna tallrikar eller trasiga fönster, men ocksa i allvarligare saker som brott i flygplansvingar eller fartygsskrov som i vär

Human-bacterial interactions play a crucial role in several essential aspects of life. Here, we describe how a secreted protein from the skin commensal Cutibacterium acnes, RoxP, functions as a sacrificial redox effector molecule that facilitates beneficial interactions with its human host by counteracting oxidative stress and reducing stress-induced inflammation. Using a combination of structural

This article surveys the reception of the Gnostic text Pistis Sophia in esoteric milieus in nineteenth- and early twentieth-century Europe. The first part of the article contains an overview of the text and scholarship on it. Then follows a study of the reception of Pistis Sophia in a broader array of esoteric circles. It becomes clear that the text was hailed as an example of ancient and great spThis article surveys the reception of the Gnostic text Pistis Sophia in esoteric milieus in nineteenth- and early twentieth-century Europe. The first part of the article contains an overview of the text and scholarship on it. Then follows a study of the reception of Pistis Sophia in a broader array of esoteric circles. It becomes clear that the text was hailed as an example of ancient and great sp

The hepatokine follistatin is elevated in patients with type 2 diabetes (T2D) and promotes hyperglycemia in mice. Here we explore the relationship of plasma follistatin levels with incident T2D and mechanisms involved. Adjusted hazard ratio (HR) per standard deviation (SD) increase in follistatin levels for T2D is 1.24 (CI: 1.04-1.47, p < 0.05) during 19-year follow-up (n = 4060, Sweden); and 1.31

ObjectiveComputerized decision‐support tools may improve diagnosis of acute myocardial infarction (AMI) among patients presenting with chest pain at the emergency department (ED). The primary aim was to assess the predictive accuracy of machine learning algorithms based on paired high‐sensitivity cardiac troponin T (hs‐cTnT) concentrations with varying sampling times, age, and sex in order to rule

Endogenous retroviruses (ERVs) make up a large fraction of mammalian genomes and are thought to contribute to human disease, including brain disorders. In the brain, aberrant activation of ERVs is a potential trigger for an inflammatory response, but mechanistic insight into this phenomenon remains lacking. Using CRISPR/Cas9-based gene disruption of the epigenetic co-repressor protein Trim28, we f

On-site hydrogen gas production from hydrogen-rich liquids offers a clean alternative to fossil fuels for combustion that is readily implemented in existing energy infrastructure. A heterogenized (POCOP)-Ir pincer catalyst can be operated at higher temperatures for higher turnover frequency, but the reaction pathway of the reported complex has not been well understood. Here, we report intermediary

Low vaccination coverage against SARS-CoV-2 (COVID-19) is a public health concern. The aim of this study was to identify barriers and motivators associated with COVID-19 vaccination and develop a vaccine acceptance scoring system. From the overall population residing in Skåne county Sweden in 2022 (n = 1 384 531), 3600 randomly selected individuals (aged ≥18 years) received a survey. Questions wer

Background/Objectives: A novel patient group with chronic pulmonary fibrosis is emerging post COVID-19. To identify patients at risk of developing post-COVID-19 lung fibrosis, we here aimed to identify systemic proteins that overlap with fibrotic markers identified in patients with idiopathic pulmonary fibrosis (IPF) and may predict COVID-19-induced lung fibrosis. Methods: Ninety-two proteins we

OBJECTIVES: Early diagnostic separation between glioblastoma (GBM) and solitary metastases (MET) is important for patient management but remains challenging when based on imaging only. The objective of this study was to assess whether amide proton transfer weighted (APTw) MRI alone or combined with dynamic susceptibility contrast (DSC) MRI parameters, including cerebral blood volume (CBV), cerebra

Background, Motivation, and ObjectiveThe demand for tissue-mimicking materials (TMMs) is increasing alongside the advancement of hybrid imaging such as photoacoustic imaging (PAI). Developing suitable TMMs for PAI is challenging due to the need to mimic both optical and acoustic tissue properties. The TMMs with tunable properties are needed for the calibration of these imaging modalities, as well

Marie Sklodowska-Curie COFUND Doctoral Programme under Horizon Europe Funded by the European Union under Horizon Europe – MSCA COFUND Grant Agreement No. 101216514 1 RAMP-UP DOCTORAL PROGRAMME: GUIDE FOR PHD APPLICANTS (CALL 1, 2026) RAMP-UP REGENERATIVE MEDICINE AND ADVANCED THERAPY MEDICINAL PRODUCTS – UNITED FOR PHD EXCELLENCE SHAPING THE FUTURE OF CELL, GENE & TISSUE’BASED THERAPIES 55 DOCTORA

https://www.stemcellcenter.lu.se/sites/stemcellcenter.lu.se/files/2026-01/RAMP%20UP_Doctoral%20Programme_Applicants%20Guide_Call%201_JAN2026.pdf - 2026-05-14

Marie Sklodowska-Curie COFUND Doctoral Programme under Horizon Europe Funded by the European Union under Horizon Europe – MSCA COFUND Grant Agreement No. 101216514 1 RAMP-UP DOCTORAL PROGRAMME: GUIDE FOR PHD APPLICANTS (CALL 1, 2026) RAMP-UP REGENERATIVE MEDICINE AND ADVANCED THERAPY MEDICINAL PRODUCTS – UNITED FOR PHD EXCELLENCE SHAPING THE FUTURE OF CELL, GENE & TISSUE’BASED THERAPIES 55 DOCTORA

https://www.stemcellcenter.lu.se/sites/stemcellcenter.lu.se/files/2026-01/RAMP%20UP_Applicants%20Guide_Call%201%202026.pdf - 2026-05-14

Möt Linnea Almö Thorsell, student på läkarprogrammet.

Master’s Dissertation Structural Mechanics CARL LÖFQUIST RESPONSE OF BUILDINGS EXPOSED TO BLAST LOAD Method Evaluation DEPARTMENT OF CONSTRUCTION SCIENCES STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--16/5216--SE (1-88) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisor: Professor PER-ERIK AUSTRELL, Div. of Structural Mechanics, LTH. Examiner: Professor KENT PERSSON, Div. of Structural Mechanics, LTH. Cop

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5216.pdf - 2026-05-11

Tidsbegränsad anställning för vissa jurister | START AKADEMIKER I STATEN SACO-S Saco-S, en lokalförening på din arbetsplats för dig som arbetar statligt Hoppa till huvudinnehåll Öppna sökruta Öppna Huvudmeny Sök på saco.se Aktuellt Saco-S överlämnar yrkanden i statlig sektor Förändringar i Saco-S avtal med Arbetsgivarverket Saco-S träffar civilministern AD-dom Saco-S mot Försäkringskassan Gallring

https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/statlig-sektor/saco-s/avtal/flexibilitet-omstallningsformaga-och-trygghet/overenskommelse-om-flexibilitet-omstallningsformaga-och-trygghet-pa-den-statliga-sektorn/tidsbegransad-anstallning-for-vissa-jurister/ - 2026-05-11